BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 23057850)

  • 1. Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.
    Cosconati S; Rizzo A; Trotta R; Pagano B; Iachettini S; De Tito S; Lauri I; Fotticchia I; Giustiniano M; Marinelli L; Giancola C; Novellino E; Biroccio A; Randazzo A
    J Med Chem; 2012 Nov; 55(22):9785-92. PubMed ID: 23057850
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW; Promontorio R; Hampel SM; Micco M; Neidle S; Parkinson GN
    J Am Chem Soc; 2012 Feb; 134(5):2723-31. PubMed ID: 22280460
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S; Haider SM; Doria F; Gunaratnam M; Neidle S
    J Am Chem Soc; 2010 Sep; 132(35):12263-72. PubMed ID: 20718414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methods of studying telomere damage induced by quadruplex-ligand complexes.
    Rizzo A; Salvati E; Biroccio A
    Methods; 2012 May; 57(1):93-9. PubMed ID: 22410593
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.
    Di Leva FS; Zizza P; Cingolani C; D'Angelo C; Pagano B; Amato J; Salvati E; Sissi C; Pinato O; Marinelli L; Cavalli A; Cosconati S; Novellino E; Randazzo A; Biroccio A
    J Med Chem; 2013 Dec; 56(23):9646-54. PubMed ID: 24256368
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer.
    Chan DS; Yang H; Kwan MH; Cheng Z; Lee P; Bai LP; Jiang ZH; Wong CY; Fong WF; Leung CH; Ma DL
    Biochimie; 2011 Jun; 93(6):1055-64. PubMed ID: 21377506
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes.
    Castor KJ; Mancini J; Fakhoury J; Weill N; Kieltyka R; Englebienne P; Avakyan N; Mittermaier A; Autexier C; Moitessier N; Sleiman HF
    ChemMedChem; 2012 Jan; 7(1):85-94. PubMed ID: 22052801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization.
    Lavrado J; Reszka AP; Moreira R; Neidle S; Paulo A
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7042-5. PubMed ID: 20952194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
    Musumeci D; Amato J; Zizza P; Platella C; Cosconati S; Cingolani C; Biroccio A; Novellino E; Randazzo A; Giancola C; Pagano B; Montesarchio D
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules.
    Pagano B; Amato J; Iaccarino N; Cingolani C; Zizza P; Biroccio A; Novellino E; Randazzo A
    ChemMedChem; 2015 Apr; 10(4):640-9. PubMed ID: 25694275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells.
    Huang FC; Chang CC; Lou PJ; Kuo IC; Chien CW; Chen CT; Shieh FY; Chang TC; Lin JJ
    Mol Cancer Res; 2008 Jun; 6(6):955-64. PubMed ID: 18515756
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding properties of human telomeric quadruplex multimers: a new route for drug design.
    Cummaro A; Fotticchia I; Franceschin M; Giancola C; Petraccone L
    Biochimie; 2011 Sep; 93(9):1392-400. PubMed ID: 21527309
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Li Z; Tan JH; He JH; Long Y; Ou TM; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2012 Jan; 47(1):299-311. PubMed ID: 22104971
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of disubstituted amidoxanthones as potential telomeric G-quadruplex DNA-binding and apoptosis-inducing agents.
    Shen R; Chen Y; Li Z; Qi H; Wang Y
    Bioorg Med Chem; 2016 Feb; 24(4):619-26. PubMed ID: 26740156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
    Amato J; Pagano A; Cosconati S; Amendola G; Fotticchia I; Iaccarino N; Marinello J; De Magis A; Capranico G; Novellino E; Pagano B; Randazzo A
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1271-1280. PubMed ID: 27836755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Tan JH; Ou TM; Hou JQ; Lu YJ; Huang SL; Luo HB; Wu JY; Huang ZS; Wong KY; Gu LQ
    J Med Chem; 2009 May; 52(9):2825-35. PubMed ID: 19354252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biaryl polyamides as a new class of DNA quadruplex-binding ligands.
    Rahman KM; Reszka AP; Gunaratnam M; Haider SM; Howard PW; Fox KR; Neidle S; Thurston DE
    Chem Commun (Camb); 2009 Jul; (27):4097-9. PubMed ID: 19568645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells.
    Franceschin M; Rizzo A; Casagrande V; Salvati E; Alvino A; Altieri A; Ciammaichella A; Iachettini S; Leonetti C; Ortaggi G; Porru M; Bianco A; Biroccio A
    ChemMedChem; 2012 Dec; 7(12):2144-54. PubMed ID: 23097341
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The orientation of the ends of G-quadruplex structures investigated using end-extended oligonucleotides.
    Sannohe Y; Sato K; Matsugami A; Shinohara K; Mashimo T; Katahira M; Sugiyama H
    Bioorg Med Chem; 2009 Mar; 17(5):1870-5. PubMed ID: 19223183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region.
    Xiong YX; Su HF; Lv P; Ma Y; Wang SK; Miao H; Liu HY; Tan JH; Ou TM; Gu LQ; Huang ZS
    Oncotarget; 2015 Nov; 6(34):35625-35. PubMed ID: 26462146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.