These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 23061798)

  • 21. Cytoprotection against beta-amyloid (Aβ) peptide-mediated oxidative damage and autophagy by Keap1 RNAi in human glioma U87mg cells.
    Youn P; Chen Y; Furgeson DY
    Neurosci Res; 2015 May; 94():70-8. PubMed ID: 25612817
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway.
    Heyninck K; Sabbe L; Chirumamilla CS; Szarc Vel Szic K; Vander Veken P; Lemmens KJA; Lahtela-Kakkonen M; Naulaerts S; Op de Beeck K; Laukens K; Van Camp G; Weseler AR; Bast A; Haenen GRMM; Haegeman G; Vanden Berghe W
    Biochem Pharmacol; 2016 Jun; 109():48-61. PubMed ID: 27045103
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling.
    Winkel AF; Engel CK; Margerie D; Kannt A; Szillat H; Glombik H; Kallus C; Ruf S; Güssregen S; Riedel J; Herling AW; von Knethen A; Weigert A; Brüne B; Schmoll D
    J Biol Chem; 2015 Nov; 290(47):28446-28455. PubMed ID: 26459563
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The molecular mechanism of Nrf2-Keap1 signaling pathway in the antioxidant defense response induced by BaP in the scallop Chlamys farreri.
    Wang H; Pan L; Xu R; Si L; Zhang X
    Fish Shellfish Immunol; 2019 Sep; 92():489-499. PubMed ID: 31220575
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.
    Takagi T; Naito Y; Okada H; Ishii T; Mizushima K; Akagiri S; Adachi S; Handa O; Kokura S; Ichikawa H; Itoh K; Yamamoto M; Matsui H; Yoshikawa T
    J Pharmacol Exp Ther; 2009 Oct; 331(1):255-64. PubMed ID: 19628634
    [TBL] [Abstract][Full Text] [Related]  

  • 26. p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway.
    Liao W; Wang Z; Fu Z; Ma H; Jiang M; Xu A; Zhang W
    Free Radic Res; 2019 Jul; 53(7):800-814. PubMed ID: 31223046
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Alterations in the Nrf2-Keap1 signaling pathway and its downstream target genes in rat brain under stress.
    Djordjevic J; Djordjevic A; Adzic M; Mitic M; Lukic I; Radojcic MB
    Brain Res; 2015 Mar; 1602():20-31. PubMed ID: 25598205
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation.
    Song MK; Lee JH; Ryoo IG; Lee SH; Ku SK; Kwak MK
    Free Radic Biol Med; 2019 Jul; 138():33-42. PubMed ID: 31059771
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds.
    MacLeod AK; McMahon M; Plummer SM; Higgins LG; Penning TM; Igarashi K; Hayes JD
    Carcinogenesis; 2009 Sep; 30(9):1571-80. PubMed ID: 19608619
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
    Rojo AI; Medina-Campos ON; Rada P; Zúñiga-Toalá A; López-Gazcón A; Espada S; Pedraza-Chaverri J; Cuadrado A
    Free Radic Biol Med; 2012 Jan; 52(2):473-87. PubMed ID: 22142471
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1.
    Sun W; Liu X; Zhang H; Song Y; Li T; Liu X; Liu Y; Guo L; Wang F; Yang T; Guo W; Wu J; Jin H; Wu H
    Free Radic Biol Med; 2017 Jul; 108():840-857. PubMed ID: 28457936
    [TBL] [Abstract][Full Text] [Related]  

  • 32. MicroRNA-200a controls Nrf2 activation by target Keap1 in hepatic stellate cell proliferation and fibrosis.
    Yang JJ; Tao H; Hu W; Liu LP; Shi KH; Deng ZY; Li J
    Cell Signal; 2014 Nov; 26(11):2381-9. PubMed ID: 25049078
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles.
    Turpaev KT
    Biochemistry (Mosc); 2013 Feb; 78(2):111-26. PubMed ID: 23581983
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.
    Williamson TP; Johnson DA; Johnson JA
    Neurotoxicology; 2012 Jun; 33(3):272-9. PubMed ID: 22342405
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
    Uruno A; Motohashi H
    Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.
    Chowdhury I; Mo Y; Gao L; Kazi A; Fisher AB; Feinstein SI
    Free Radic Biol Med; 2009 Jan; 46(2):146-53. PubMed ID: 18973804
    [TBL] [Abstract][Full Text] [Related]  

  • 37. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
    Jain A; Lamark T; Sjøttem E; Larsen KB; Awuh JA; Øvervatn A; McMahon M; Hayes JD; Johansen T
    J Biol Chem; 2010 Jul; 285(29):22576-91. PubMed ID: 20452972
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
    Hori R; Yamaguchi K; Sato H; Watanabe M; Tsutsumi K; Iwamoto S; Abe M; Onodera H; Nakamura S; Nakai R
    Cancer Med; 2019 Mar; 8(3):1157-1168. PubMed ID: 30735010
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z; Zhang S; Chan JY; Zhang DD
    Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.
    Lister A; Nedjadi T; Kitteringham NR; Campbell F; Costello E; Lloyd B; Copple IM; Williams S; Owen A; Neoptolemos JP; Goldring CE; Park BK
    Mol Cancer; 2011 Apr; 10():37. PubMed ID: 21489257
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.