BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 23063129)

  • 1. Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.
    Teperino R; Amann S; Bayer M; McGee SL; Loipetzberger A; Connor T; Jaeger C; Kammerer B; Winter L; Wiche G; Dalgaard K; Selvaraj M; Gaster M; Lee-Young RS; Febbraio MA; Knauf C; Cani PD; Aberger F; Penninger JM; Pospisilik JA; Esterbauer H
    Cell; 2012 Oct; 151(2):414-26. PubMed ID: 23063129
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.
    Wang Y; Zhou Z; Walsh CT; McMahon AP
    Proc Natl Acad Sci U S A; 2009 Feb; 106(8):2623-8. PubMed ID: 19196978
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
    Lee H; Ko HW
    Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
    Jung B; Padula D; Burtscher I; Landerer C; Lutter D; Theis F; Messias AC; Geerlof A; Sattler M; Kremmer E; Boldt K; Ueffing M; Lickert H
    PLoS One; 2016; 11(2):e0149477. PubMed ID: 26901434
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.
    Wang Y; Arvanites AC; Davidow L; Blanchard J; Lam K; Yoo JW; Coy S; Rubin LL; McMahon AP
    ACS Chem Biol; 2012 Jun; 7(6):1040-8. PubMed ID: 22554036
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.
    Wilson CW; Chen MH; Chuang PT
    PLoS One; 2009; 4(4):e5182. PubMed ID: 19365551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.
    Bijlsma MF; Damhofer H; Roelink H
    Sci Signal; 2012 Aug; 5(238):ra60. PubMed ID: 22912493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.
    Yang C; Chen W; Chen Y; Jiang J
    Cell Res; 2012 Nov; 22(11):1593-604. PubMed ID: 22986504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting of Smoothened for therapeutic gain.
    Ruat M; Hoch L; Faure H; Rognan D
    Trends Pharmacol Sci; 2014 May; 35(5):237-46. PubMed ID: 24703627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of hedgehog signaling promotes white adipose tissue browning.
    Zhang Z; Zhang XX; Liu ZF; Guo XR; Cui XW; Ji CB; Zhong H; Chi X
    Mol Cell Endocrinol; 2020 Dec; 518():110970. PubMed ID: 32738443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.
    Arensdorf AM; Dillard ME; Menke JM; Frank MW; Rock CO; Ogden SK
    Cell Rep; 2017 Jun; 19(10):2074-2087. PubMed ID: 28591579
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.
    Fan CW; Chen B; Franco I; Lu J; Shi H; Wei S; Wang C; Wu X; Tang W; Roth MG; Williams NS; Hirsch E; Chen C; Lum L
    Chem Biol; 2014 Dec; 21(12):1680-9. PubMed ID: 25484239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Smoothened-dependent and -independent pathways in mammalian noncanonical Hedgehog signaling.
    Faria AVS; Akyala AI; Parikh K; Brüggemann LW; Spek CA; Cao W; Bruno MJ; Bijlsma MF; Fuhler GM; Peppelenbosch MP
    J Biol Chem; 2019 Jun; 294(25):9787-9798. PubMed ID: 30992365
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smoothened as a new therapeutic target for human osteosarcoma.
    Hirotsu M; Setoguchi T; Sasaki H; Matsunoshita Y; Gao H; Nagao H; Kunigou O; Komiya S
    Mol Cancer; 2010 Jan; 9():5. PubMed ID: 20067614
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.
    Spann AL; Yuan K; Goliwas KF; Steg AD; Kaushik DD; Kwon YJ; Frost AR
    Int J Oncol; 2015 Jul; 47(1):269-79. PubMed ID: 25997440
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.
    Caparrós-Martín JA; Valencia M; Reytor E; Pacheco M; Fernandez M; Perez-Aytes A; Gean E; Lapunzina P; Peters H; Goodship JA; Ruiz-Perez VL
    Hum Mol Genet; 2013 Jan; 22(1):124-39. PubMed ID: 23026747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
    Desai PB; Stuck MW; Lv B; Pazour GJ
    J Cell Biol; 2020 Jul; 219(7):. PubMed ID: 32435793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.