BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 23064555)

  • 1. LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage.
    Yamamoto K; Troeberg L; Scilabra SD; Pelosi M; Murphy CL; Strickland DK; Nagase H
    FASEB J; 2013 Feb; 27(2):511-21. PubMed ID: 23064555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
    Yamamoto K; Owen K; Parker AE; Scilabra SD; Dudhia J; Strickland DK; Troeberg L; Nagase H
    J Biol Chem; 2014 Mar; 289(10):6462-6474. PubMed ID: 24474687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.
    Song RH; Tortorella MD; Malfait AM; Alston JT; Yang Z; Arner EC; Griggs DW
    Arthritis Rheum; 2007 Feb; 56(2):575-85. PubMed ID: 17265492
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis.
    Yamamoto K; Santamaria S; Botkjaer KA; Dudhia J; Troeberg L; Itoh Y; Murphy G; Nagase H
    Arthritis Rheumatol; 2017 Jun; 69(6):1246-1256. PubMed ID: 28235248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes.
    Ismail HM; Yamamoto K; Vincent TL; Nagase H; Troeberg L; Saklatvala J
    Arthritis Rheumatol; 2015 Jul; 67(7):1826-36. PubMed ID: 25776267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protective effect of lentivirus-mediated siRNA targeting ADAMTS-5 on cartilage degradation in a rat model of osteoarthritis.
    Chu X; You H; Yuan X; Zhao W; Li W; Guo X
    Int J Mol Med; 2013 May; 31(5):1222-8. PubMed ID: 23546441
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Research progress of a disintegrin and metalloproteinase with thrombospondin motif 4 and 5 in osteoarthritis].
    Ji Q; Zhang Q; Wang Y
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2013 Sep; 27(9):1080-4. PubMed ID: 24279019
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
    Troeberg L; Fushimi K; Khokha R; Emonard H; Ghosh P; Nagase H
    FASEB J; 2008 Oct; 22(10):3515-24. PubMed ID: 18632849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aggrecanase and aggrecan degradation in osteoarthritis: a review.
    Huang K; Wu LD
    J Int Med Res; 2008; 36(6):1149-60. PubMed ID: 19094423
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CCN1 (Cyr61) Is Overexpressed in Human Osteoarthritic Cartilage and Inhibits ADAMTS-4 (Aggrecanase 1) Activity.
    Chijiiwa M; Mochizuki S; Kimura T; Abe H; Tanaka Y; Fujii Y; Shimizu H; Enomoto H; Toyama Y; Okada Y
    Arthritis Rheumatol; 2015 Jun; 67(6):1557-67. PubMed ID: 25709087
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.
    Verma P; Dalal K
    J Cell Biochem; 2011 Dec; 112(12):3507-14. PubMed ID: 21815191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of age-dependent expression of aggrecan and ADAMTSs in mandibular condylar cartilage, tibial growth plate, and articular cartilage in rats.
    Mitani H; Takahashi I; Onodera K; Bae JW; Sato T; Takahashi N; Sasano Y; Igarashi K; Mitani H
    Histochem Cell Biol; 2006 Sep; 126(3):371-80. PubMed ID: 16583222
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
    Little CB; Flannery CR; Hughes CE; Mort JS; Roughley PJ; Dent C; Caterson B
    Biochem J; 1999 Nov; 344 Pt 1(Pt 1):61-8. PubMed ID: 10548534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes.
    Huang CY; Lai KY; Hung LF; Wu WL; Liu FC; Ho LJ
    Rheumatology (Oxford); 2011 Aug; 50(8):1379-89. PubMed ID: 21482542
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
    Durigova M; Troeberg L; Nagase H; Roughley PJ; Mort JS
    Eur Cell Mater; 2011 Jan; 21():31-45. PubMed ID: 21225593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture.
    Coughlan TC; Crawford A; Goldring MB; Hatton PV; Barker MD
    J Tissue Eng Regen Med; 2010 Dec; 4(8):611-8. PubMed ID: 20568084
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2).
    Santamaria S; Yamamoto K; Botkjaer K; Tape C; Dyson MR; McCafferty J; Murphy G; Nagase H
    Biochem J; 2015 Nov; 471(3):391-401. PubMed ID: 26303525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.
    Wilkinson DJ; Wang H; Habgood A; Lamb HK; Thompson P; Hawkins AR; Désilets A; Leduc R; Steinmetzer T; Hammami M; Lee MS; Craik CS; Watson S; Lin H; Milner JM; Rowan AD
    Arthritis Rheumatol; 2017 Aug; 69(8):1601-1611. PubMed ID: 28464560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    He Y; Zheng Q; Jiang M; Sun S; Christiansen TG; Kassem M; Karsdal MA; Bay-Jensen AC
    PLoS One; 2015; 10(4):e0122700. PubMed ID: 25909781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CCAAT/enhancer binding protein β regulates expression of matrix metalloproteinase-3 in arthritis.
    Tsushima H; Okazaki K; Hayashida M; Ushijima T; Iwamoto Y
    Ann Rheum Dis; 2012 Jan; 71(1):99-107. PubMed ID: 21917825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.