BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

85 related articles for article (PubMed ID: 23066949)

  • 1. Protein-ligand interaction study of CpOGA in complex with GlcNAcstatin.
    Sousa PR; de Alencar NA; Lima AH; Lameira J; Alves CN
    Chem Biol Drug Des; 2013 Feb; 81(2):284-90. PubMed ID: 23066949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantum mechanical/molecular mechanical molecular dynamics simulation of wild-type and seven mutants of CpNagJ in complex with PUGNAc.
    Lameira J; Alves CN; Moliner V; Martí S; Castillo R; Tuñón I
    J Phys Chem B; 2010 May; 114(20):7029-36. PubMed ID: 20429600
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enzyme molecular mechanism as a starting point to design new inhibitors: a theoretical study of O-GlcNAcase.
    Lameira J; Alves CN; Tuñón I; Martí S; Moliner V
    J Phys Chem B; 2011 May; 115(20):6764-75. PubMed ID: 21542586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A quantum mechanics/molecular mechanics study of the protein-ligand interaction of two potent inhibitors of human O-GlcNAcase: PUGNAc and NAG-thiazoline.
    Lameira J; Alves CN; Moliner V; Martí S; Kanaan N; Tuñón I
    J Phys Chem B; 2008 Nov; 112(45):14260-6. PubMed ID: 18939790
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational analysis of human OGA structure in complex with PUGNAc and NAG-thiazoline derivatives.
    de Alencar NA; Sousa PR; Silva JR; Lameira J; Alves CN; Martí S; Moliner V
    J Chem Inf Model; 2012 Oct; 52(10):2775-83. PubMed ID: 22937904
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor.
    Shanmugasundaram B; Debowski AW; Dennis RJ; Davies GJ; Vocadlo DJ; Vasella A
    Chem Commun (Camb); 2006 Nov; (42):4372-4. PubMed ID: 17057847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation.
    Dorfmueller HC; Borodkin VS; Schimpl M; van Aalten DM
    Biochem J; 2009 May; 420(2):221-7. PubMed ID: 19275764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis.
    Li J; Li Z; Li T; Lin L; Zhang Y; Guo L; Xu Y; Zhao W; Wang P
    Biochemistry (Mosc); 2012 Feb; 77(2):194-200. PubMed ID: 22348480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis.
    Rao FV; Dorfmueller HC; Villa F; Allwood M; Eggleston IM; van Aalten DM
    EMBO J; 2006 Apr; 25(7):1569-78. PubMed ID: 16541109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations.
    Li T; Guo L; Zhang Y; Wang J; Li Z; Lin L; Zhang Z; Li L; Lin J; Zhao W; Li J; Wang PG
    Carbohydr Res; 2011 Jul; 346(9):1083-92. PubMed ID: 21514574
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety.
    Kim EJ; Perreira M; Thomas CJ; Hanover JA
    J Am Chem Soc; 2006 Apr; 128(13):4234-5. PubMed ID: 16568991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of microbial β-N-acetylhexosaminidases by 4-deoxy- and galacto-analogues of NAG-thiazoline.
    Krejzová J; Kalachova L; Šimon P; Pelantová H; Slámová K; Křen V
    Bioorg Med Chem Lett; 2014 Nov; 24(22):5321-3. PubMed ID: 25442323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.
    Dorfmueller HC; Borodkin VS; Schimpl M; Shepherd SM; Shpiro NA; van Aalten DM
    J Am Chem Soc; 2006 Dec; 128(51):16484-5. PubMed ID: 17177381
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Active-pocket size differentiating insectile from bacterial chitinolytic β-N-acetyl-D-hexosaminidases.
    Liu T; Zhang H; Liu F; Chen L; Shen X; Yang Q
    Biochem J; 2011 Sep; 438(3):467-74. PubMed ID: 21692744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase.
    Ryšlavá H; Kalendová A; Doubnerová V; Skočdopol P; Kumar V; Kukačka Z; Pompach P; Vaněk O; Slámová K; Bojarová P; Kulik N; Ettrich R; Křen V; Bezouška K
    FEBS J; 2011 Jul; 278(14):2469-84. PubMed ID: 21564548
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of GlcNAc-processing glycosidases by C-6-azido-NAG-thiazoline and its derivatives.
    Krejzová J; Simon P; Kalachova L; Kulik N; Bojarová P; Marhol P; Pelantová H; Cvačka J; Ettrich R; Slámová K; Křen V
    Molecules; 2014 Mar; 19(3):3471-88. PubMed ID: 24658571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active site dynamics and combined quantum mechanics/molecular mechanics (QM/MM) modelling of a HIV-1 reverse transcriptase/DNA/dTTP complex.
    Rungrotmongkol T; Mulholland AJ; Hannongbua S
    J Mol Graph Model; 2007 Jul; 26(1):1-13. PubMed ID: 17046299
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The interaction of a carbohydrate-binding module from a Clostridium perfringens N-acetyl-beta-hexosaminidase with its carbohydrate receptor.
    Ficko-Blean E; Boraston AB
    J Biol Chem; 2006 Dec; 281(49):37748-57. PubMed ID: 16990278
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships.
    Greig IR; Macauley MS; Williams IH; Vocadlo DJ
    J Am Chem Soc; 2009 Sep; 131(37):13415-22. PubMed ID: 19715310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds.
    Dorfmueller HC; van Aalten DM
    FEBS Lett; 2010 Feb; 584(4):694-700. PubMed ID: 20026047
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.