85 related articles for article (PubMed ID: 23066949)
21. Elevation of cellular O-GlcNAcylation level by a potent and selective O-GlcNAcase inhibitor based on tetrahydroimidazopyridine scaffold.
Li T; Li Z; Li J; Wang J; Guo L; Wang PG; Zhao W
Bioorg Med Chem Lett; 2012 Nov; 22(22):6854-7. PubMed ID: 23058883
[TBL] [Abstract][Full Text] [Related]
22. A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase.
Stubbs KA; Zhang N; Vocadlo DJ
Org Biomol Chem; 2006 Mar; 4(5):839-45. PubMed ID: 16493467
[TBL] [Abstract][Full Text] [Related]
23. Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation.
Dong L; Shen S; Chen W; Xu D; Yang Q; Lu H; Zhang J
J Chem Inf Model; 2019 Oct; 59(10):4374-4382. PubMed ID: 31487462
[TBL] [Abstract][Full Text] [Related]
24. Streptozotocin-induced beta-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells.
Gao Y; Parker GJ; Hart GW
Arch Biochem Biophys; 2000 Nov; 383(2):296-302. PubMed ID: 11185566
[TBL] [Abstract][Full Text] [Related]
25. Synthesis of NAM-thiazoline derivatives as novel O-GlcNAcase inhibitors.
Kong H; Chen W; Liu T; Lu H; Yang Q; Dong Y; Liang X; Jin S; Zhang J
Carbohydr Res; 2016 Jun; 429():54-61. PubMed ID: 27233493
[TBL] [Abstract][Full Text] [Related]
26. Role of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis.
Manuel SG; Ragunath C; Sait HB; Izano EA; Kaplan JB; Ramasubbu N
FEBS J; 2007 Nov; 274(22):5987-99. PubMed ID: 17949435
[TBL] [Abstract][Full Text] [Related]
27. Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog.
Toleman C; Paterson AJ; Shin R; Kudlow JE
Biochem Biophys Res Commun; 2006 Feb; 340(2):526-34. PubMed ID: 16376298
[TBL] [Abstract][Full Text] [Related]
28. Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.
Ho CW; Popat SD; Liu TW; Tsai KC; Ho MJ; Chen WH; Yang AS; Lin CH
ACS Chem Biol; 2010 May; 5(5):489-97. PubMed ID: 20187655
[TBL] [Abstract][Full Text] [Related]
29. Glucosamine modulates TNF-α-induced ICAM-1 expression and function through O-linked and N-linked glycosylation in human retinal pigment epithelial cells.
Chen CL; Liang CM; Chen YH; Tai MC; Lu DW; Chen JT
Invest Ophthalmol Vis Sci; 2012 Apr; 53(4):2281-91. PubMed ID: 22427561
[TBL] [Abstract][Full Text] [Related]
30. Understanding the structural and energetic basis of inhibitor and substrate bound to the full-length NS3/4A: insights from molecular dynamics simulation, binding free energy calculation and network analysis.
Xue W; Wang M; Jin X; Liu H; Yao X
Mol Biosyst; 2012 Oct; 8(10):2753-65. PubMed ID: 22833015
[TBL] [Abstract][Full Text] [Related]
31. O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation.
Vocadlo DJ
Curr Opin Chem Biol; 2012 Dec; 16(5-6):488-97. PubMed ID: 23146438
[TBL] [Abstract][Full Text] [Related]
32. Molecular dynamics simulations of the interaction of glucose with imidazole in aqueous solution.
Chen M; Bomble YJ; Himmel ME; Brady JW
Carbohydr Res; 2012 Feb; 349():73-7. PubMed ID: 22248861
[TBL] [Abstract][Full Text] [Related]
33. A quantum mechanics/molecular mechanics study of the protein-ligand interaction for inhibitors of HIV-1 integrase.
Alves CN; Martí S; Castillo R; Andrés J; Moliner V; Tuñón I; Silla E
Chemistry; 2007; 13(27):7715-24. PubMed ID: 17570717
[TBL] [Abstract][Full Text] [Related]
34. Computational study of β-N-acetylhexosaminidase from Talaromyces flavus, a glycosidase with high substrate flexibility.
Kulik N; Slámová K; Ettrich R; Křen V
BMC Bioinformatics; 2015 Jan; 16():28. PubMed ID: 25627923
[TBL] [Abstract][Full Text] [Related]
35. Promiscuity in alkaline phosphatase superfamily. Unraveling evolution through molecular simulations.
López-Canut V; Roca M; Bertrán J; Moliner V; Tuñón I
J Am Chem Soc; 2011 Aug; 133(31):12050-62. PubMed ID: 21609015
[TBL] [Abstract][Full Text] [Related]
36. Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.
Ettrich R; Kopecký V; Hofbauerová K; Baumruk V; Novák P; Pompach P; Man P; Plíhal O; Kutý M; Kulik N; Sklenár J; Ryslavá H; Kren V; Bezouska K
BMC Struct Biol; 2007 May; 7():32. PubMed ID: 17509134
[TBL] [Abstract][Full Text] [Related]
37. Why does beta-secretase zymogen possess catalytic activity? Molecular modeling and molecular dynamics simulation studies.
Zuo Z; Gang C; Zou H; Mok PC; Zhu W; Chen K; Jiang H
Comput Biol Chem; 2007 Jun; 31(3):186-95. PubMed ID: 17500040
[TBL] [Abstract][Full Text] [Related]
38. Enzymatic characterization and inhibition of the nuclear variant of human O-GlcNAcase.
Macauley MS; Vocadlo DJ
Carbohydr Res; 2009 Jun; 344(9):1079-84. PubMed ID: 19423084
[TBL] [Abstract][Full Text] [Related]
39. Elucidating the nature of the Streptomyces plicatus beta-hexosaminidase-bound intermediate using ab initio molecular dynamics simulations.
Greig IR; Zahariev F; Withers SG
J Am Chem Soc; 2008 Dec; 130(51):17620-8. PubMed ID: 19053474
[TBL] [Abstract][Full Text] [Related]
40. Hybrid QM/MM and DFT investigations of the catalytic mechanism and inhibition of the dinuclear zinc metallo-beta-lactamase CcrA from Bacteroides fragilis.
Park H; Brothers EN; Merz KM
J Am Chem Soc; 2005 Mar; 127(12):4232-41. PubMed ID: 15783205
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
