These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 23071106)

  • 1. Potentiation of sulfonylurea action by an EPAC-selective cAMP analog in INS-1 cells: comparison of tolbutamide and gliclazide and a potential role for EPAC activation of a 2-APB-sensitive Ca2+ influx.
    Jarrard RE; Wang Y; Salyer AE; Pratt EP; Soderling IM; Guerra ML; Lange AM; Broderick HJ; Hockerman GH
    Mol Pharmacol; 2013 Jan; 83(1):191-205. PubMed ID: 23071106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
    Chepurny OG; Leech CA; Kelley GG; Dzhura I; Dzhura E; Li X; Rindler MJ; Schwede F; Genieser HG; Holz GG
    J Biol Chem; 2009 Apr; 284(16):10728-36. PubMed ID: 19244230
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.
    Leech CA; Dzhura I; Chepurny OG; Schwede F; Genieser HG; Holz GG
    Islets; 2010; 2(2):72-81. PubMed ID: 20428467
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG; Kelley GG; Dzhura I; Leech CA; Roe MW; Dzhura E; Li X; Schwede F; Genieser HG; Holz GG
    Am J Physiol Endocrinol Metab; 2010 Mar; 298(3):E622-33. PubMed ID: 20009023
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells.
    Wang Y; Jarrard RE; Pratt EP; Guerra ML; Salyer AE; Lange AM; Soderling IM; Hockerman GH
    Mol Endocrinol; 2014 Apr; 28(4):458-76. PubMed ID: 24506535
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+-sensitive K+ channels in rat mesenteric artery.
    Roberts OL; Kamishima T; Barrett-Jolley R; Quayle JM; Dart C
    J Physiol; 2013 Oct; 591(20):5107-23. PubMed ID: 23959673
    [TBL] [Abstract][Full Text] [Related]  

  • 7. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
    Kang G; Chepurny OG; Malester B; Rindler MJ; Rehmann H; Bos JL; Schwede F; Coetzee WA; Holz GG
    J Physiol; 2006 Jun; 573(Pt 3):595-609. PubMed ID: 16613879
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells.
    Kang G; Leech CA; Chepurny OG; Coetzee WA; Holz GG
    J Physiol; 2008 Mar; 586(5):1307-19. PubMed ID: 18202100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.
    Dzhura I; Chepurny OG; Leech CA; Roe MW; Dzhura E; Xu X; Lu Y; Schwede F; Genieser HG; Smrcka AV; Holz GG
    Islets; 2011; 3(3):121-8. PubMed ID: 21478675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.
    Mariot P; Gilon P; Nenquin M; Henquin JC
    Diabetes; 1998 Mar; 47(3):365-73. PubMed ID: 9519741
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.
    Kang G; Joseph JW; Chepurny OG; Monaco M; Wheeler MB; Bos JL; Schwede F; Genieser HG; Holz GG
    J Biol Chem; 2003 Mar; 278(10):8279-85. PubMed ID: 12496249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.
    Kelley GG; Chepurny OG; Schwede F; Genieser HG; Leech CA; Roe MW; Li X; Dzhura I; Dzhura E; Afshari P; Holz GG
    Islets; 2009; 1(3):260-5. PubMed ID: 21099281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stimulation of bursting in pre-Bötzinger neurons by Epac through calcium release and modulation of TRPM4 and K-ATP channels.
    Mironov SL; Skorova EY
    J Neurochem; 2011 Apr; 117(2):295-308. PubMed ID: 21281309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential modulation of Cav1.2 and Cav1.3-mediated glucose-stimulated insulin secretion by cAMP in INS-1 cells: distinct roles for exchange protein directly activated by cAMP 2 (Epac2) and protein kinase A.
    Liu G; Jacobo SM; Hilliard N; Hockerman GH
    J Pharmacol Exp Ther; 2006 Jul; 318(1):152-60. PubMed ID: 16565168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.
    Henquin JC; Nenquin M
    Endocrinology; 2014 Sep; 155(9):3274-87. PubMed ID: 24977470
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L; Nygaard G; Kopperud R; Krakstad C; Døskeland SO; Selheim F
    Biochem Biophys Res Commun; 2013 Aug; 437(4):603-8. PubMed ID: 23850619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion.
    Hoque KM; Woodward OM; van Rossum DB; Zachos NC; Chen L; Leung GP; Guggino WB; Guggino SE; Tse CM
    J Gen Physiol; 2010 Jan; 135(1):43-58. PubMed ID: 20038525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cooperation between cAMP signalling and sulfonylurea in insulin secretion.
    Shibasaki T; Takahashi T; Takahashi H; Seino S
    Diabetes Obes Metab; 2014 Sep; 16 Suppl 1():118-25. PubMed ID: 25200305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Calcium/calmodulin-dependent kinase 2 mediates Epac-induced spontaneous transient outward currents in rat vascular smooth muscle.
    Humphries ESA; Kamishima T; Quayle JM; Dart C
    J Physiol; 2017 Sep; 595(18):6147-6164. PubMed ID: 28731505
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.
    Tian YA; Johnson G; Ashcroft SJ
    Diabetes; 1998 Nov; 47(11):1722-6. PubMed ID: 9792541
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.