258 related articles for article (PubMed ID: 23071437)
1. De novo GTP biosynthesis is critical for virulence of the fungal pathogen Cryptococcus neoformans.
Morrow CA; Valkov E; Stamp A; Chow EW; Lee IR; Wronski A; Williams SJ; Hill JM; Djordjevic JT; Kappler U; Kobe B; Fraser JA
PLoS Pathog; 2012; 8(10):e1002957. PubMed ID: 23071437
[TBL] [Abstract][Full Text] [Related]
2. Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus.
Morrow CA; Stamp A; Valkov E; Kobe B; Fraser JA
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2010 Sep; 66(Pt 9):1104-7. PubMed ID: 20823538
[TBL] [Abstract][Full Text] [Related]
3.
Chitty JL; Blake KL; Blundell RD; Koh YQAE; Thompson M; Robertson AAB; Butler MS; Cooper MA; Kappler U; Williams SJ; Kobe B; Fraser JA
J Biol Chem; 2017 Jul; 292(28):11829-11839. PubMed ID: 28559277
[TBL] [Abstract][Full Text] [Related]
4. Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.
Kummari LK; Butler MS; Furlong E; Blundell R; Nouwens A; Silva AB; Kappler U; Fraser JA; Kobe B; Cooper MA; Robertson AAB
Bioorg Med Chem; 2018 Nov; 26(20):5408-5419. PubMed ID: 30322754
[TBL] [Abstract][Full Text] [Related]
5. Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.
Ji Y; Gu J; Makhov AM; Griffith JD; Mitchell BS
J Biol Chem; 2006 Jan; 281(1):206-12. PubMed ID: 16243838
[TBL] [Abstract][Full Text] [Related]
6. Molecular typing, in vitro susceptibility and virulence of Cryptococcus neoformans/Cryptococcus gattii species complex clinical isolates from south-eastern Brazil.
Grizante Barião PH; Tonani L; Cocio TA; Martinez R; Nascimento É; von Zeska Kress MR
Mycoses; 2020 Dec; 63(12):1341-1351. PubMed ID: 32869413
[TBL] [Abstract][Full Text] [Related]
7. Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans.
Blundell RD; Williams SJ; Arras SD; Chitty JL; Blake KL; Ericsson DJ; Tibrewal N; Rohr J; Koh YQ; Kappler U; Robertson AA; Butler MS; Cooper MA; Kobe B; Fraser JA
ACS Infect Dis; 2016 Sep; 2(9):651-663. PubMed ID: 27759389
[TBL] [Abstract][Full Text] [Related]
8. AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
Wizrah MSI; Chua SMH; Luo Z; Manik MK; Pan M; Whyte JML; Robertson AAB; Kappler U; Kobe B; Fraser JA
J Biol Chem; 2022 Oct; 298(10):102453. PubMed ID: 36063996
[TBL] [Abstract][Full Text] [Related]
9. The functional basis of mycophenolic acid resistance in Candida albicans IMP dehydrogenase.
Köhler GA; Gong X; Bentink S; Theiss S; Pagani GM; Agabian N; Hedstrom L
J Biol Chem; 2005 Mar; 280(12):11295-302. PubMed ID: 15665003
[TBL] [Abstract][Full Text] [Related]
10. Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.
Digits JA; Hedstrom L
Biochemistry; 1999 Nov; 38(46):15388-97. PubMed ID: 10563825
[TBL] [Abstract][Full Text] [Related]
11. Molecular epidemiology and in vitro antifungal susceptibility testing of 108 clinical Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato isolates from Denmark.
Hagen F; Hare Jensen R; Meis JF; Arendrup MC
Mycoses; 2016 Sep; 59(9):576-84. PubMed ID: 27061834
[TBL] [Abstract][Full Text] [Related]
12. Mechanism of action of mycophenolate mofetil.
Ransom JT
Ther Drug Monit; 1995 Dec; 17(6):681-4. PubMed ID: 8588241
[TBL] [Abstract][Full Text] [Related]
13. Dissection of the molecular basis of mycophenolate resistance in Saccharomyces cerevisiae.
Jenks MH; Reines D
Yeast; 2005 Nov; 22(15):1181-90. PubMed ID: 16278936
[TBL] [Abstract][Full Text] [Related]
14. Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
Chua SMH; Wizrah MSI; Luo Z; Lim BYJ; Kappler U; Kobe B; Fraser JA
J Biol Chem; 2021 Oct; 297(4):101091. PubMed ID: 34416230
[TBL] [Abstract][Full Text] [Related]
15. Antifungal susceptibility of clinical and environmental Cryptococcus neoformans and Cryptococcus gattii isolates in Jabalpur, a city of Madhya Pradesh in Central India.
Gutch RS; Nawange SR; Singh SM; Yadu R; Tiwari A; Gumasta R; Kavishwar A
Braz J Microbiol; 2015; 46(4):1125-33. PubMed ID: 26691471
[TBL] [Abstract][Full Text] [Related]
16. Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.
Sintchak MD; Fleming MA; Futer O; Raybuck SA; Chambers SP; Caron PR; Murcko MA; Wilson KP
Cell; 1996 Jun; 85(6):921-30. PubMed ID: 8681386
[TBL] [Abstract][Full Text] [Related]
17. Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase.
Zhang R; Evans G; Rotella FJ; Westbrook EM; Beno D; Huberman E; Joachimiak A; Collart FR
Biochemistry; 1999 Apr; 38(15):4691-700. PubMed ID: 10200156
[TBL] [Abstract][Full Text] [Related]
18. Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Prosise GL; Luecke H
J Mol Biol; 2003 Feb; 326(2):517-27. PubMed ID: 12559919
[TBL] [Abstract][Full Text] [Related]
19. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.
Lockhart SR; Fothergill AW; Iqbal N; Bolden CB; Grossman NT; Garvey EP; Brand SR; Hoekstra WJ; Schotzinger RJ; Ottinger E; Patterson TF; Wiederhold NP
Antimicrob Agents Chemother; 2016 Apr; 60(4):2528-31. PubMed ID: 26787697
[TBL] [Abstract][Full Text] [Related]
20. Molecular types of Cryptococcus neoformans and Cryptococcus gattii in Western Australia and correlation with antifungal susceptibility.
Lee GA; Arthur I; Merritt A; Leung M
Med Mycol; 2019 Nov; 57(8):1004-1010. PubMed ID: 30649538
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]