BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 23072492)

  • 1. Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood-brain barriers studied with (R)-[11C]verapamil positron emission tomography.
    Müllauer J; Kuntner C; Bauer M; Bankstahl JP; Müller M; Voskuyl RA; Langer O; Syvänen S
    EJNMMI Res; 2012 Oct; 2(1):58. PubMed ID: 23072492
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tariquidar-induced P-glycoprotein inhibition at the rat blood-brain barrier studied with (R)-11C-verapamil and PET.
    Bankstahl JP; Kuntner C; Abrahim A; Karch R; Stanek J; Wanek T; Wadsak W; Kletter K; Müller M; Löscher W; Langer O
    J Nucl Med; 2008 Aug; 49(8):1328-35. PubMed ID: 18632828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A pilot study to assess the efficacy of tariquidar to inhibit P-glycoprotein at the human blood-brain barrier with (R)-11C-verapamil and PET.
    Wagner CC; Bauer M; Karch R; Feurstein T; Kopp S; Chiba P; Kletter K; Löscher W; Müller M; Zeitlinger M; Langer O
    J Nucl Med; 2009 Dec; 50(12):1954-61. PubMed ID: 19910428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assessment of cerebral P-glycoprotein expression and function with PET by combined [11C]inhibitor and [11C]substrate scans in rats.
    Müllauer J; Karch R; Bankstahl JP; Bankstahl M; Stanek J; Wanek T; Mairinger S; Müller M; Löscher W; Langer O; Kuntner C
    Nucl Med Biol; 2013 Aug; 40(6):755-63. PubMed ID: 23774004
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
    Wanek T; Römermann K; Mairinger S; Stanek J; Sauberer M; Filip T; Traxl A; Kuntner C; Pahnke J; Bauer F; Erker T; Löscher W; Müller M; Langer O
    Mol Pharm; 2015 Sep; 12(9):3214-25. PubMed ID: 26202880
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetic Modeling of (
    García-Varela L; García DV; Kakiuchi T; Ohba H; Nishiyama S; Tago T; Elsinga PH; Tsukada H; Colabufo NA; Dierckx RAJO; van Waarde A; Toyohara J; Boellaard R; Luurtsema G
    Mol Pharm; 2021 Jan; 18(1):416-428. PubMed ID: 33315404
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[(11)C]verapamil PET.
    Kuntner C; Bankstahl JP; Bankstahl M; Stanek J; Wanek T; Stundner G; Karch R; Brauner R; Meier M; Ding X; Müller M; Löscher W; Langer O
    Eur J Nucl Med Mol Imaging; 2010 May; 37(5):942-53. PubMed ID: 20016890
    [TBL] [Abstract][Full Text] [Related]  

  • 8. (R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus.
    Syvänen S; Luurtsema G; Molthoff CF; Windhorst AD; Huisman MC; Lammertsma AA; Voskuyl RA; de Lange EC
    BMC Med Imaging; 2011 Jan; 11():1. PubMed ID: 21199574
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of 11C-tariquidar and 11C-elacridar with P-glycoprotein and breast cancer resistance protein at the human blood-brain barrier.
    Bauer M; Karch R; Zeitlinger M; Stanek J; Philippe C; Wadsak W; Mitterhauser M; Jäger W; Haslacher H; Müller M; Langer O
    J Nucl Med; 2013 Aug; 54(8):1181-7. PubMed ID: 23833270
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
    Wanek T; Kuntner C; Bankstahl JP; Bankstahl M; Stanek J; Sauberer M; Mairinger S; Strommer S; Wacheck V; Löscher W; Erker T; Müller M; Langer O
    Eur J Nucl Med Mol Imaging; 2012 Jan; 39(1):149-59. PubMed ID: 21983837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat data.
    Bauer M; Zeitlinger M; Karch R; Matzneller P; Stanek J; Jäger W; Böhmdorfer M; Wadsak W; Mitterhauser M; Bankstahl JP; Löscher W; Koepp M; Kuntner C; Müller M; Langer O
    Clin Pharmacol Ther; 2012 Feb; 91(2):227-33. PubMed ID: 22166851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil.
    Verbeek J; Syvänen S; Schuit RC; Eriksson J; de Lange EC; Windhorst AD; Luurtsema G; Lammertsma AA
    Nucl Med Biol; 2012 May; 39(4):530-9. PubMed ID: 22226023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Approaching complete inhibition of P-glycoprotein at the human blood-brain barrier: an (R)-[11C]verapamil PET study.
    Bauer M; Karch R; Zeitlinger M; Philippe C; Römermann K; Stanek J; Maier-Salamon A; Wadsak W; Jäger W; Hacker M; Müller M; Langer O
    J Cereb Blood Flow Metab; 2015 May; 35(5):743-6. PubMed ID: 25669913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased permeability-glycoprotein inhibition at the human blood-brain barrier can be safely achieved by performing PET during peak plasma concentrations of tariquidar.
    Kreisl WC; Bhatia R; Morse CL; Woock AE; Zoghbi SS; Shetty HU; Pike VW; Innis RB
    J Nucl Med; 2015 Jan; 56(1):82-7. PubMed ID: 25500831
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide.
    Kreisl WC; Liow JS; Kimura N; Seneca N; Zoghbi SS; Morse CL; Herscovitch P; Pike VW; Innis RB
    J Nucl Med; 2010 Apr; 51(4):559-66. PubMed ID: 20237038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Altered GABAA receptor density and unaltered blood-brain barrier transport in a kainate model of epilepsy: an in vivo study using 11C-flumazenil and PET.
    Syvänen S; Labots M; Tagawa Y; Eriksson J; Windhorst AD; Lammertsma AA; de Lange EC; Voskuyl RA
    J Nucl Med; 2012 Dec; 53(12):1974-83. PubMed ID: 23143088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[
    Bauer M; Wulkersdorfer B; Karch R; Philippe C; Jäger W; Stanek J; Wadsak W; Hacker M; Zeitlinger M; Langer O
    Br J Clin Pharmacol; 2017 Sep; 83(9):1991-1999. PubMed ID: 28401570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [11C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein.
    Froklage FE; Syvänen S; Hendrikse NH; Huisman MC; Molthoff CF; Tagawa Y; Reijneveld JC; Heimans JJ; Lammertsma AA; Eriksson J; de Lange EC; Voskuyl RA
    EJNMMI Res; 2012 Mar; 2():12. PubMed ID: 22455873
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats.
    Verbeek J; Eriksson J; Syvänen S; Labots M; de Lange EC; Voskuyl RA; Mooijer MP; Rongen M; Lammertsma AA; Windhorst AD
    EJNMMI Res; 2012 Jul; 2(1):36. PubMed ID: 22747744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier.
    Bankstahl JP; Bankstahl M; Kuntner C; Stanek J; Wanek T; Meier M; Ding XQ; Müller M; Langer O; Löscher W
    J Neurosci; 2011 Jun; 31(24):8803-11. PubMed ID: 21677164
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.