These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

97 related articles for article (PubMed ID: 23073172)

  • 1. Evaluation and computational characterization of the facilitated transport of Glc carbon C-1 oxime reactivators across a blood brain barrier model.
    Bhonsle JB; Causey R; Oyler BL; Bartolucci C; Lamba D; Pesaresi A; Bhamare NK; Soojhawon I; Garcia GE
    Chem Biol Interact; 2013 Mar; 203(1):129-34. PubMed ID: 23073172
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel oximes as blood-brain barrier penetrating cholinesterase reactivators.
    Garcia GE; Campbell AJ; Olson J; Moorad-Doctor D; Morthole VI
    Chem Biol Interact; 2010 Sep; 187(1-3):199-206. PubMed ID: 20227398
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates.
    Chambers JE; Chambers HW; Meek EC; Pringle RB
    Chem Biol Interact; 2013 Mar; 203(1):135-8. PubMed ID: 23123249
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesterase.
    Bhattacharjee AK; Marek E; Le HT; Gordon RK
    Eur J Med Chem; 2012 Mar; 49():229-38. PubMed ID: 22309910
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.
    Mercey G; Verdelet T; Renou J; Kliachyna M; Baati R; Nachon F; Jean L; Renard PY
    Acc Chem Res; 2012 May; 45(5):756-66. PubMed ID: 22360473
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Passive diffusion of acetylcholinesterase oxime reactivators through the blood-brain barrier: influence of molecular structure.
    Karasova JZ; Pohanka M; Musilek K; Zemek F; Kuca K
    Toxicol In Vitro; 2010 Sep; 24(6):1838-44. PubMed ID: 20546883
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase.
    de Koning MC; van Grol M; Noort D
    Toxicol Lett; 2011 Sep; 206(1):54-9. PubMed ID: 21504785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents.
    Renou J; Mercey G; Verdelet T; Păunescu E; Gillon E; Arboléas M; Loiodice M; Kliachyna M; Baati R; Nachon F; Jean L; Renard PY
    Chem Biol Interact; 2013 Mar; 203(1):81-4. PubMed ID: 23111374
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties.
    Bhattacharjee AK; Kuca K; Musilek K; Gordon RK
    Chem Res Toxicol; 2010 Jan; 23(1):26-36. PubMed ID: 20028185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetics and pharmacodynamics of some oximes and associated therapeutic consequences: a critical review.
    Voicu VA; Bajgar J; Medvedovici A; Radulescu FS; Miron DS
    J Appl Toxicol; 2010 Nov; 30(8):719-29. PubMed ID: 20635332
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural requirements for effective oximes--evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes.
    Worek F; Wille T; Koller M; Thiermann H
    Chem Biol Interact; 2013 Mar; 203(1):125-8. PubMed ID: 22827894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro investigation of efficacy of new reactivators on OPC inhibited rat brain acetylcholinesterase.
    Atanasov VN; Petrova I; Dishovsky C
    Chem Biol Interact; 2013 Mar; 203(1):139-43. PubMed ID: 23220589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice.
    dos Santos AA; dos Santos DB; Ribeiro RP; Colle D; Peres KC; Hermes J; Barbosa AM; Dafré AL; de Bem AF; Kuca K; Farina M
    Neurotoxicology; 2011 Dec; 32(6):888-95. PubMed ID: 21723318
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach.
    Worek F; Aurbek N; Wille T; Eyer P; Thiermann H
    J Enzyme Inhib Med Chem; 2011 Jun; 26(3):303-8. PubMed ID: 20807085
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate.
    Lorke DE; Hasan MY; Arafat K; Kuca K; Musilek K; Schmitt A; Petroianu GA
    J Appl Toxicol; 2008 May; 28(4):422-9. PubMed ID: 18344198
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM; Brecht KM; Sweeney RE
    Chem Biol Interact; 2013 Mar; 203(1):72-6. PubMed ID: 22982773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species.
    Luo C; Chambers C; Yang Y; Saxena A
    Chem Biol Interact; 2010 Sep; 187(1-3):185-90. PubMed ID: 20096273
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic interactions of a homologous series of bispyridinium monooximes (HGG oximes) with native and phosphonylated human acetylcholinesterase.
    Worek F; Bierwisch A; Wille T; Koller M; Thiermann H
    Toxicol Lett; 2012 Jul; 212(1):29-32. PubMed ID: 22561105
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose.
    Shih TM; Skovira JW; O'Donnell JC; McDonough JH
    Toxicol Mech Methods; 2009 Sep; 19(6-7):386-400. PubMed ID: 19778239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relationships between the antidotal efficacy and structure, PK/PD parameters and bio-relevant molecular descriptors of AChE reactivating oximes: inclusion and integration to biopharmaceutical classification systems.
    Voicu V; Rădulescu FŞ; Medvedovici A
    Expert Opin Drug Metab Toxicol; 2015 Jan; 11(1):95-109. PubMed ID: 25373357
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.