172 related articles for article (PubMed ID: 23073462)
1. Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction.
Contini A; Cappelletti G; Cartelli D; Fontana G; Gelmi ML
Mol Biosyst; 2012 Oct; 8(12):3254-61. PubMed ID: 23073462
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site.
Xiang F; Yu J; Yin R; Ma Y; Yu L
Z Naturforsch C J Biosci; 2009; 64(7-8):551-6. PubMed ID: 19791508
[TBL] [Abstract][Full Text] [Related]
3. Elucidating the mechanism of action of the clinically approved taxanes: a comprehensive comparison of local and allosteric effects.
Churchill CD; Klobukowski M; Tuszynski JA
Chem Biol Drug Des; 2015 Nov; 86(5):1253-66. PubMed ID: 26032329
[TBL] [Abstract][Full Text] [Related]
4. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
[TBL] [Abstract][Full Text] [Related]
5. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
Cai P; Lu P; Sharom FJ; Fang WS
Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
[TBL] [Abstract][Full Text] [Related]
6. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site.
Edler MC; Buey RM; Gussio R; Marcus AI; Vanderwal CD; Sorensen EJ; Díaz JF; Giannakakou P; Hamel E
Biochemistry; 2005 Aug; 44(34):11525-38. PubMed ID: 16114889
[TBL] [Abstract][Full Text] [Related]
7. Stabilization of microtubules by taxane diterpenoids: insight from docking and MD simulations.
Yadava U; Gupta H; Roychoudhury M
J Biol Phys; 2015 Mar; 41(2):117-33. PubMed ID: 25542396
[TBL] [Abstract][Full Text] [Related]
8. The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.
Ferlini C; Raspaglio G; Mozzetti S; Cicchillitti L; Filippetti F; Gallo D; Fattorusso C; Campiani G; Scambia G
Cancer Res; 2005 Mar; 65(6):2397-405. PubMed ID: 15781655
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
Ganesh T; Yang C; Norris A; Glass T; Bane S; Ravindra R; Banerjee A; Metaferia B; Thomas SL; Giannakakou P; Alcaraz AA; Lakdawala AS; Snyder JP; Kingston DG
J Med Chem; 2007 Feb; 50(4):713-25. PubMed ID: 17263521
[TBL] [Abstract][Full Text] [Related]
10. Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis.
Jordan MA; Ojima I; Rosas F; Distefano M; Wilson L; Scambia G; Ferlini C
Chem Biol; 2002 Jan; 9(1):93-101. PubMed ID: 11841942
[TBL] [Abstract][Full Text] [Related]
11. Molecular mobility of nitroxyl-labelled taxol during tubulin assembly.
Nicholov R; Kingston DG; Chordia MC; DiCosmo F
FEBS Lett; 1997 Mar; 405(1):73-6. PubMed ID: 9094427
[TBL] [Abstract][Full Text] [Related]
12. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
[TBL] [Abstract][Full Text] [Related]
13. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
[TBL] [Abstract][Full Text] [Related]
14. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
[TBL] [Abstract][Full Text] [Related]
15. Cyclostreptin and microtubules: is a low-affinity binding site required?
Prussia AJ; Yang Y; Geballe MT; Snyder JP
Chembiochem; 2010 Jan; 11(1):101-9. PubMed ID: 19946930
[TBL] [Abstract][Full Text] [Related]
16. Characterization of the reversible taxol-induced polymerization of plant tubulin into microtubules.
Bokros CL; Hugdahl JD; Hanesworth VR; Murthy JV; Morejohn LC
Biochemistry; 1993 Apr; 32(13):3437-47. PubMed ID: 8096395
[TBL] [Abstract][Full Text] [Related]
17. Structural intermediates in the assembly of taxoid-induced microtubules and GDP-tubulin double rings: time-resolved X-ray scattering.
Diaz JF; Andreu JM; Diakun G; Towns-Andrews E; Bordas J
Biophys J; 1996 May; 70(5):2408-20. PubMed ID: 9172767
[TBL] [Abstract][Full Text] [Related]
18. Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives.
Shanker N; Kingston DG; Ganesh T; Yang C; Alcaraz AA; Geballe MT; Banerjee A; McGee D; Snyder JP; Bane S
Biochemistry; 2007 Oct; 46(41):11514-27. PubMed ID: 17892304
[TBL] [Abstract][Full Text] [Related]
19. Structural insight into the stabilization of microtubules by taxanes.
Prota AE; Lucena-Agell D; Ma Y; Estevez-Gallego J; Li S; Bargsten K; Josa-Prado F; Altmann KH; Gaillard N; Kamimura S; Mühlethaler T; Gago F; Oliva MA; Steinmetz MO; Fang WS; Díaz JF
Elife; 2023 Mar; 12():. PubMed ID: 36876916
[TBL] [Abstract][Full Text] [Related]
20. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]