224 related articles for article (PubMed ID: 23075628)
1. Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging.
Dallaire A; Garand C; Paquel ER; Mitchell SJ; de Cabo R; Simard MJ; Lebel M
Aging (Albany NY); 2012 Sep; 4(9):636-47. PubMed ID: 23075628
[TBL] [Abstract][Full Text] [Related]
2. A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint.
Lee SJ; Yook JS; Han SM; Koo HS
Development; 2004 Jun; 131(11):2565-75. PubMed ID: 15115755
[TBL] [Abstract][Full Text] [Related]
3. Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
Hui CW; St-Pierre MK; Detuncq J; Aumailley L; Dubois MJ; Couture V; Skuk D; Marette A; Tremblay JP; Lebel M; Tremblay MÈ
Brain Behav Immun; 2018 Oct; 73():450-469. PubMed ID: 29908963
[TBL] [Abstract][Full Text] [Related]
4. Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Aumailley L; Garand C; Dubois MJ; Johnson FB; Marette A; Lebel M
PLoS One; 2015; 10(10):e0140292. PubMed ID: 26447695
[TBL] [Abstract][Full Text] [Related]
5. Vitamin C restores healthy aging in a mouse model for Werner syndrome.
Massip L; Garand C; Paquet ER; Cogger VC; O'Reilly JN; Tworek L; Hatherell A; Taylor CG; Thorin E; Zahradka P; Le Couteur DG; Lebel M
FASEB J; 2010 Jan; 24(1):158-72. PubMed ID: 19741171
[TBL] [Abstract][Full Text] [Related]
6. Roles of Caenorhabditis elegans WRN Helicase in DNA Damage Responses, and a Comparison with Its Mammalian Homolog: A Mini-Review.
Ryu JS; Koo HS
Gerontology; 2016; 62(3):296-303. PubMed ID: 26347143
[TBL] [Abstract][Full Text] [Related]
7. Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span.
Dallaire A; Proulx S; Simard MJ; Lebel M
BMC Genomics; 2014 Oct; 15(1):940. PubMed ID: 25346348
[TBL] [Abstract][Full Text] [Related]
8. Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin.
Lebel M; Massip L; Garand C; Thorin E
Ann N Y Acad Sci; 2010 Jun; 1197():40-4. PubMed ID: 20536831
[TBL] [Abstract][Full Text] [Related]
9. Biochemical characterization of the WRN-1 RecQ helicase of Caenorhabditis elegans.
Hyun M; Bohr VA; Ahn B
Biochemistry; 2008 Jul; 47(28):7583-93. PubMed ID: 18558712
[TBL] [Abstract][Full Text] [Related]
10. MUT-7 Provides Molecular Insight into the Werner Syndrome Exonuclease.
Hsu TY; Hsu LN; Chen SY; Juang BT
Cells; 2021 Dec; 10(12):. PubMed ID: 34943966
[TBL] [Abstract][Full Text] [Related]
11. The Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks.
Lee SJ; Gartner A; Hyun M; Ahn B; Koo HS
PLoS Genet; 2010 Jan; 6(1):e1000801. PubMed ID: 20062519
[TBL] [Abstract][Full Text] [Related]
12. Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide.
Labbé A; Turaga RV; Paquet ER; Garand C; Lebel M
BMC Genomics; 2010 Feb; 11():127. PubMed ID: 20175907
[TBL] [Abstract][Full Text] [Related]
13. Physical and functional interactions of Caenorhabditis elegans WRN-1 helicase with RPA-1.
Hyun M; Park S; Kim E; Kim DH; Lee SJ; Koo HS; Seo YS; Ahn B
Biochemistry; 2012 Feb; 51(7):1336-45. PubMed ID: 22257160
[TBL] [Abstract][Full Text] [Related]
14. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
[TBL] [Abstract][Full Text] [Related]
15. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
Aggarwal M; Brosh RM
Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
[TBL] [Abstract][Full Text] [Related]
16. Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation.
Li K; Casta A; Wang R; Lozada E; Fan W; Kane S; Ge Q; Gu W; Orren D; Luo J
J Biol Chem; 2008 Mar; 283(12):7590-8. PubMed ID: 18203716
[TBL] [Abstract][Full Text] [Related]
17. The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.
Kamath-Loeb AS; Welcsh P; Waite M; Adman ET; Loeb LA
J Biol Chem; 2004 Dec; 279(53):55499-505. PubMed ID: 15489508
[TBL] [Abstract][Full Text] [Related]
18. Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Aumailley L; Dubois MJ; Garand C; Marette A; Lebel M
Exp Gerontol; 2015 Dec; 72():192-203. PubMed ID: 26521679
[TBL] [Abstract][Full Text] [Related]
19. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
Machwe A; Lozada EM; Xiao L; Orren DK
BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
[TBL] [Abstract][Full Text] [Related]
20. Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.
de Renty C; Ellis NA
Ageing Res Rev; 2017 Jan; 33():36-51. PubMed ID: 27238185
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]