These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 23080121)

  • 1. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
    Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
    Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
    Williams RS; Moncalian G; Williams JS; Yamada Y; Limbo O; Shin DS; Groocock LM; Cahill D; Hitomi C; Guenther G; Moiani D; Carney JP; Russell P; Tainer JA
    Cell; 2008 Oct; 135(1):97-109. PubMed ID: 18854158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.
    Langerak P; Mejia-Ramirez E; Limbo O; Russell P
    PLoS Genet; 2011 Sep; 7(9):e1002271. PubMed ID: 21931565
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling.
    Porter-Goff ME; Rhind N
    Mol Biol Cell; 2009 Apr; 20(7):2096-107. PubMed ID: 19211838
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.
    Limbo O; Porter-Goff ME; Rhind N; Russell P
    Mol Cell Biol; 2011 Feb; 31(3):573-83. PubMed ID: 21098122
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in
    Li Y; Wang J; Zhou G; Lajeunesse M; Le N; Stawicki BN; Corcino YL; Berkner KL; Runge KW
    Genetics; 2017 May; 206(1):481-496. PubMed ID: 28292918
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are not genetically separable.
    Jensen KL; Russell P
    Nucleic Acids Res; 2016 Sep; 44(17):8241-9. PubMed ID: 27325741
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1.
    Limbo O; Yamada Y; Russell P
    Mol Biol Cell; 2018 Jun; 29(11):1389-1399. PubMed ID: 29851556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
    Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
    Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.
    Limbo O; Chahwan C; Yamada Y; de Bruin RA; Wittenberg C; Russell P
    Mol Cell; 2007 Oct; 28(1):134-46. PubMed ID: 17936710
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation of Conserved Mre11 Residues Alter Protein Dynamics to Separate Nuclease Functions.
    Rahman S; Beikzadeh M; Canny MD; Kaur N; Latham MP
    J Mol Biol; 2020 May; 432(10):3289-3308. PubMed ID: 32246962
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.
    Akamatsu Y; Murayama Y; Yamada T; Nakazaki T; Tsutsui Y; Ohta K; Iwasaki H
    Mol Cell Biol; 2008 Jun; 28(11):3639-51. PubMed ID: 18378696
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
    Hopfner KP; Karcher A; Craig L; Woo TT; Carney JP; Tainer JA
    Cell; 2001 May; 105(4):473-85. PubMed ID: 11371344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.
    Wen Q; Scorah J; Phear G; Rodgers G; Rodgers S; Meuth M
    Mol Biol Cell; 2008 Apr; 19(4):1693-705. PubMed ID: 18256278
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular basis of ataxia telangiectasia and related diseases.
    Ball LG; Xiao W
    Acta Pharmacol Sin; 2005 Aug; 26(8):897-907. PubMed ID: 16038621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
    Lavin MF
    Oncogene; 2007 Dec; 26(56):7749-58. PubMed ID: 18066087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpoint.
    Willis N; Rhind N
    Genetics; 2010 Apr; 184(4):887-97. PubMed ID: 20065069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.