BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 23082912)

  • 1. PfRIO-2 kinase is a potential therapeutic target of antimalarial protein kinase inhibitors.
    Nag S; Prasad K; Bhowmick A; Deshmukh R; Trivedi V
    Curr Drug Discov Technol; 2013 Mar; 10(1):85-91. PubMed ID: 23082912
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Skeletal hybridization and PfRIO-2 kinase modeling for synthesis of α-pyrone analogs as anti-malarial agent.
    Parveen A; Chakraborty A; Konreddy AK; Chakravarty H; Sharon A; Trivedi V; Bal C
    Eur J Med Chem; 2013; 70():607-12. PubMed ID: 24211636
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.
    Geyer JA; Keenan SM; Woodard CL; Thompson PA; Gerena L; Nichols DA; Gutteridge CE; Waters NC
    Bioorg Med Chem Lett; 2009 Apr; 19(7):1982-5. PubMed ID: 19250824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids.
    Strödke B; Gehring AP; Bracher F
    Arch Pharm (Weinheim); 2015 Feb; 348(2):125-31. PubMed ID: 25664630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
    González-Bacerio J; Maluf SEC; Méndez Y; Pascual I; Florent I; Melo PMS; Budu A; Ferreira JC; Moreno E; Carmona AK; Rivera DG; Alonso Del Rivero M; Gazarini ML
    Bioorg Med Chem; 2017 Sep; 25(17):4628-4636. PubMed ID: 28728898
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploration of new drug-like inhibitors for serine/threonine protein phosphatase 5 of Plasmodium falciparum: a docking and simulation study.
    Gupta S; Jadaun A; Kumar H; Raj U; Varadwaj PK; Rao AR
    J Biomol Struct Dyn; 2015; 33(11):2421-41. PubMed ID: 25967133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development.
    Green JL; Moon RW; Whalley D; Bowyer PW; Wallace C; Rochani A; Nageshan RK; Howell SA; Grainger M; Jones HM; Ansell KH; Chapman TM; Taylor DL; Osborne SA; Baker DA; Tatu U; Holder AA
    Antimicrob Agents Chemother; 2015 Dec; 60(3):1464-75. PubMed ID: 26711771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nima- and Aurora-related kinases of malaria parasites.
    Carvalho TG; Doerig C; Reininger L
    Biochim Biophys Acta; 2013 Jul; 1834(7):1336-45. PubMed ID: 23462523
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Temperature does matter-an additional dimension in kinase inhibitor development.
    Strauch M; Heyd F
    FEBS J; 2021 May; 288(10):3148-3153. PubMed ID: 32946682
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plasmodium kinases as targets for new-generation antimalarials.
    Lucet IS; Tobin A; Drewry D; Wilks AF; Doerig C
    Future Med Chem; 2012 Dec; 4(18):2295-310. PubMed ID: 23234552
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors.
    Deprez-Poulain R; Flipo M; Piveteau C; Leroux F; Dassonneville S; Florent I; Maes L; Cos P; Deprez B
    J Med Chem; 2012 Dec; 55(24):10909-17. PubMed ID: 23176597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.
    Laurent D; Jullian V; Parenty A; Knibiehler M; Dorin D; Schmitt S; Lozach O; Lebouvier N; Frostin M; Alby F; Maurel S; Doerig C; Meijer L; Sauvain M
    Bioorg Med Chem; 2006 Jul; 14(13):4477-82. PubMed ID: 16513357
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downstream effects of haemoglobinase inhibition in Plasmodium falciparum-infected erythrocytes.
    Naughton JA; Nasizadeh S; Bell A
    Mol Biochem Parasitol; 2010 Oct; 173(2):81-7. PubMed ID: 20478341
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.
    Lemercier G; Fernandez-Montalvan A; Shaw JP; Kugelstadt D; Bomke J; Domostoj M; Schwarz MK; Scheer A; Kappes B; Leroy D
    Biochemistry; 2009 Jul; 48(27):6379-89. PubMed ID: 19507895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasmodium falciparum protein kinase as a potential therapeutic target for antimalarial drugs development.
    Mahmud F; Lee PC; Abdul Wahab H; Mustaffa KMF; Leow CH; Azhar R; Lai NS
    Trop Biomed; 2020 Sep; 37(3):822-841. PubMed ID: 33612795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
    Crowther GJ; Hillesland HK; Keyloun KR; Reid MC; Lafuente-Monasterio MJ; Ghidelli-Disse S; Leonard SE; He P; Jones JC; Krahn MM; Mo JS; Dasari KS; Fox AM; Boesche M; El Bakkouri M; Rivas KL; Leroy D; Hui R; Drewes G; Maly DJ; Van Voorhis WC; Ojo KK
    PLoS One; 2016; 11(3):e0149996. PubMed ID: 26934697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Susceptibility of Plasmodium falciparum to glutamate dehydrogenase inhibitors--a possible new antimalarial target.
    Aparicio IM; Marín-Menéndez A; Bell A; Engel PC
    Mol Biochem Parasitol; 2010 Aug; 172(2):152-5. PubMed ID: 20399810
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.
    Bhattacharjee AK; Geyer JA; Woodard CL; Kathcart AK; Nichols DA; Prigge ST; Li Z; Mott BT; Waters NC
    J Med Chem; 2004 Oct; 47(22):5418-26. PubMed ID: 15481979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploring the structural requirements in multiple chemical scaffolds for the selective inhibition of Plasmodium falciparum calcium-dependent protein kinase-1 (PfCDPK-1) by 3D-pharmacophore modelling, and docking studies.
    Aher RB; Roy K
    SAR QSAR Environ Res; 2017 May; 28(5):390-414. PubMed ID: 28562086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.
    Gardiner DL; Skinner-Adams TS; Brown CL; Andrews KT; Stack CM; McCarthy JS; Dalton JP; Trenholme KR
    Expert Rev Anti Infect Ther; 2009 Nov; 7(9):1087-98. PubMed ID: 19883329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.