BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 23085102)

  • 1. Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.
    Daniels-Wells TR; Helguera G; Rodríguez JA; Leoh LS; Erb MA; Diamante G; Casero D; Pellegrini M; Martínez-Maza O; Penichet ML
    Toxicol In Vitro; 2013 Feb; 27(1):220-31. PubMed ID: 23085102
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conjugation of an anti transferrin receptor IgG3-avidin fusion protein with biotinylated saporin results in significant enhancement of its cytotoxicity against malignant hematopoietic cells.
    Daniels TR; Ng PP; Delgado T; Lynch MR; Schiller G; Helguera G; Penichet ML
    Mol Cancer Ther; 2007 Nov; 6(11):2995-3008. PubMed ID: 18025284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy of an Anti-transferrin Receptor 1 Antibody Against AIDS-related Non-Hodgkin Lymphoma: A Brief Communication.
    Daniels-Wells TR; Widney DP; Leoh LS; Martínez-Maza O; Penichet ML
    J Immunother; 2015 Oct; 38(8):307-10. PubMed ID: 26325374
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of NF-kappaB and Akt pathways by an antibody-avidin fusion protein sensitizes malignant B-cells to cisplatin-induced apoptosis.
    Suzuki E; Daniels TR; Helguera G; Penichet ML; Umezawa K; Bonavida B
    Int J Oncol; 2010 May; 36(5):1299-307. PubMed ID: 20372806
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An antibody-based multifaceted approach targeting the human transferrin receptor for the treatment of B-cell malignancies.
    Daniels TR; Ortiz-Sánchez E; Luria-Pérez R; Quintero R; Helguera G; Bonavida B; Martínez-Maza O; Penichet ML
    J Immunother; 2011; 34(6):500-8. PubMed ID: 21654517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter.
    Leoh LS; Morizono K; Kershaw KM; Chen IS; Penichet ML; Daniels-Wells TR
    J Gene Med; 2014; 16(1-2):11-27. PubMed ID: 24436117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytotoxic activity of an anti-transferrin receptor immunotoxin on normal and leukemic human hematopoietic progenitors.
    Cazzola M; Bergamaschi G; Dezza L; D'Uva R; Ponchio L; Rosti V; Ascari E
    Cancer Res; 1991 Jan; 51(2):536-41. PubMed ID: 1985771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells.
    Rodríguez JA; Luria-Pérez R; López-Valdés HE; Casero D; Daniels TR; Patel S; Avila D; Leuchter R; So S; Ortiz-Sánchez E; Bonavida B; Martínez-Maza O; Charles AC; Pellegrini M; Helguera G; Penichet ML
    Leuk Lymphoma; 2011 Nov; 52(11):2169-78. PubMed ID: 21870996
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Efficacy and Mechanism of Antitumor Activity of an Antibody Targeting Transferrin Receptor 1 in Mouse Models of Human Multiple Myeloma.
    Leoh LS; Kim YK; Candelaria PV; Martínez-Maza O; Daniels-Wells TR; Penichet ML
    J Immunol; 2018 May; 200(10):3485-3494. PubMed ID: 29654211
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1.
    Leoh LS; Daniels-Wells TR; Martínez-Maza O; Penichet ML
    Mol Immunol; 2015 Oct; 67(2 Pt B):407-15. PubMed ID: 26232328
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting TfR1 with the ch128.1/IgG1 Antibody Inhibits EBV-driven Lymphomagenesis in Immunosuppressed Mice Bearing EBV
    Martínez LE; Daniels-Wells TR; Guo Y; Magpantay LI; Candelaria PV; Penichet ML; Martínez-Maza O; Epeldegui M
    Mol Cancer Ther; 2021 Sep; 20(9):1592-1602. PubMed ID: 34158342
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor.
    Rodríguez JA; Helguera G; Daniels TR; Neacato II; López-Valdés HE; Charles AC; Penichet ML
    J Control Release; 2007 Dec; 124(1-2):35-42. PubMed ID: 17884229
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor.
    Ng PP; Helguera G; Daniels TR; Lomas SZ; Rodriguez JA; Schiller G; Bonavida B; Morrison SL; Penichet ML
    Blood; 2006 Oct; 108(8):2745-54. PubMed ID: 16804109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An IgG1 Version of the Anti-transferrin Receptor 1 Antibody ch128.1 Shows Significant Antitumor Activity Against Different Xenograft Models of Multiple Myeloma: A Brief Communication.
    Daniels-Wells TR; Candelaria PV; Leoh LS; Nava M; Martínez-Maza O; Penichet ML
    J Immunother; 2020; 43(2):48-52. PubMed ID: 31693515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Saporin, a ribosome-inactivating protein used to prepare immunotoxins, induces cell death via apoptosis.
    Bergamaschi G; Perfetti V; Tonon L; Novella A; Lucotti C; Danova M; Glennie MJ; Merlini G; Cazzola M
    Br J Haematol; 1996 Jun; 93(4):789-94. PubMed ID: 8703804
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunotoxins containing saporin linked to different CD2 monoclonal antibodies: in vitro evaluation.
    Tazzari PL; Bolognesi A; De Totero D; Lemoli RM; Fortuna A; Conte R; Crumpton MJ; Stirpe F
    Br J Haematol; 1994 Jan; 86(1):97-105. PubMed ID: 7912101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transferrin toxin but not transferrin receptor immunotoxin is influenced by free transferrin and iron saturation.
    Gosselaar PH; van-Dijk AJ; de-Gast GC; Polito L; Bolognesi A; Vooijs WC; Verheul AF; Krouwer HG; Marx JJ
    Eur J Clin Invest; 2002 Mar; 32 Suppl 1():61-9. PubMed ID: 11886434
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic cells: functional relevance of iron, the receptor, and reactive oxygen species.
    Ortiz-Sánchez E; Daniels TR; Helguera G; Martinez-Maza O; Bonavida B; Penichet ML
    Leukemia; 2009 Jan; 23(1):59-70. PubMed ID: 18946492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted delivery of saporin toxin by monoclonal antibody to the transcobalamin receptor, TCblR/CD320.
    Quadros EV; Nakayama Y; Sequeira JM
    Mol Cancer Ther; 2010 Nov; 9(11):3033-40. PubMed ID: 20858723
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells.
    Ng PP; Dela Cruz JS; Sorour DN; Stinebaugh JM; Shin SU; Shin DS; Morrison SL; Penichet ML
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10706-11. PubMed ID: 12149472
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.