BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 23092446)

  • 1. The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy.
    Fang F; Liu L; Yang Y; Tamaki Z; Wei J; Marangoni RG; Bhattacharyya S; Summer RS; Ye B; Varga J
    Arthritis Res Ther; 2012 Oct; 14(5):R229. PubMed ID: 23092446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.
    Wei J; Zhu H; Komura K; Lord G; Tomcik M; Wang W; Doniparthi S; Tamaki Z; Hinchcliff M; Distler JH; Varga J
    Ann Rheum Dis; 2014 Feb; 73(2):446-54. PubMed ID: 23515440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
    Ghosh AK; Bhattacharyya S; Lakos G; Chen SJ; Mori Y; Varga J
    Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis.
    Wei J; Ghosh AK; Sargent JL; Komura K; Wu M; Huang QQ; Jain M; Whitfield ML; Feghali-Bostwick C; Varga J
    PLoS One; 2010 Nov; 5(11):e13778. PubMed ID: 21072170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A20 suppresses canonical Smad-dependent fibroblast activation: novel function for an endogenous inflammatory modulator.
    Bhattacharyya S; Wang W; Graham LV; Varga J
    Arthritis Res Ther; 2016 Oct; 18(1):216. PubMed ID: 27716397
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.
    McCoy SS; Reed TJ; Berthier CC; Tsou PS; Liu J; Gudjonsson JE; Khanna D; Kahlenberg JM
    Rheumatology (Oxford); 2017 Nov; 56(11):1970-1981. PubMed ID: 28968684
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma.
    Wu M; Melichian DS; Chang E; Warner-Blankenship M; Ghosh AK; Varga J
    Am J Pathol; 2009 Feb; 174(2):519-33. PubMed ID: 19147827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-HT
    Chaturvedi S; Misra DP; Prasad N; Rastogi K; Singh H; Rai MK; Agarwal V
    Int J Rheum Dis; 2018 Dec; 21(12):2128-2138. PubMed ID: 30207074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.
    Marangoni RG; Masui Y; Fang F; Korman B; Lord G; Lee J; Lakota K; Wei J; Scherer PE; Otvos L; Yamauchi T; Kubota N; Kadowaki T; Asano Y; Sato S; Tourtellotte WG; Varga J
    Sci Rep; 2017 Jun; 7(1):4397. PubMed ID: 28667272
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.
    Bhattacharyya S; Kelley K; Melichian DS; Tamaki Z; Fang F; Su Y; Feng G; Pope RM; Budinger GR; Mutlu GM; Lafyatis R; Radstake T; Feghali-Bostwick C; Varga J
    Am J Pathol; 2013 Jan; 182(1):192-205. PubMed ID: 23141927
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J; Palumbo-Zerr K; Ruzehaji N; Tomcik M; Zerr P; Dees C; Distler A; Beyer C; Schneider H; Distler O; Schett G; Allanore Y; Distler JH
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Levels of adiponectin, a marker for PPAR-gamma activity, correlate with skin fibrosis in systemic sclerosis: potential utility as biomarker?
    Lakota K; Wei J; Carns M; Hinchcliff M; Lee J; Whitfield ML; Sodin-Semrl S; Varga J
    Arthritis Res Ther; 2012 May; 14(3):R102. PubMed ID: 22548780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
    Lakos G; Takagawa S; Chen SJ; Ferreira AM; Han G; Masuda K; Wang XJ; DiPietro LA; Varga J
    Am J Pathol; 2004 Jul; 165(1):203-17. PubMed ID: 15215176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased expression of latent TGF-β-binding protein 4 affects the fibrotic process in scleroderma by TGF-β/SMAD signaling.
    Lu J; Liu Q; Wang L; Tu W; Chu H; Ding W; Jiang S; Ma Y; Shi X; Pu W; Zhou X; Jin L; Wang J; Wu W
    Lab Invest; 2017 May; 97(5):591-601. PubMed ID: 28263294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis.
    Kapoor M; McCann M; Liu S; Huh K; Denton CP; Abraham DJ; Leask A
    Arthritis Rheum; 2009 Sep; 60(9):2822-9. PubMed ID: 19714649
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts.
    Vaamonde-Garcia C; Malaise O; Charlier E; Deroyer C; Neuville S; Gillet P; Kurth W; Meijide-Failde R; Malaise MG; de Seny D
    Biochem Pharmacol; 2019 Jul; 165():66-78. PubMed ID: 30936016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts.
    Shi-wen X; Eastwood M; Stratton RJ; Denton CP; Leask A; Abraham DJ
    Rheumatology (Oxford); 2010 Feb; 49(2):259-63. PubMed ID: 20007285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.
    Ghosh AK; Bhattacharyya S; Lafyatis R; Farina G; Yu J; Thimmapaya B; Wei J; Varga J
    J Invest Dermatol; 2013 May; 133(5):1302-10. PubMed ID: 23303459
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis.
    Korman B; Marangoni RG; Lord G; Olefsky J; Tourtellotte W; Varga J
    Arthritis Res Ther; 2018 Jul; 20(1):145. PubMed ID: 29996896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients.
    Stratton R; Shiwen X; Martini G; Holmes A; Leask A; Haberberger T; Martin GR; Black CM; Abraham D
    J Clin Invest; 2001 Jul; 108(2):241-50. PubMed ID: 11457877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.