319 related articles for article (PubMed ID: 23103253)
1. HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.
Elorza A; Soro-Arnáiz I; Meléndez-Rodríguez F; Rodríguez-Vaello V; Marsboom G; de Cárcer G; Acosta-Iborra B; Albacete-Albacete L; Ordóñez A; Serrano-Oviedo L; Giménez-Bachs JM; Vara-Vega A; Salinas A; Sánchez-Prieto R; Martín del Río R; Sánchez-Madrid F; Malumbres M; Landázuri MO; Aragonés J
Mol Cell; 2012 Dec; 48(5):681-91. PubMed ID: 23103253
[TBL] [Abstract][Full Text] [Related]
2. Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma.
Liu W; Chen H; Wong N; Haynes W; Baker CM; Wang X
Cancer Lett; 2017 May; 394():65-75. PubMed ID: 28257806
[TBL] [Abstract][Full Text] [Related]
3. Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma.
Sourbier C; Srivastava G; Ghosh MC; Ghosh S; Yang Y; Gupta G; Degraff W; Krishna MC; Mitchell JB; Rouault TA; Linehan WM
Oncotarget; 2012 Nov; 3(11):1472-82. PubMed ID: 23178531
[TBL] [Abstract][Full Text] [Related]
4. Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.
Luu VD; Boysen G; Struckmann K; Casagrande S; von Teichman A; Wild PJ; Sulser T; Schraml P; Moch H
Clin Cancer Res; 2009 May; 15(10):3297-304. PubMed ID: 19401348
[TBL] [Abstract][Full Text] [Related]
5. Reciprocal regulation of hypoxia-inducible factor 2α and GLI1 expression associated with the radioresistance of renal cell carcinoma.
Zhou J; Wu K; Gao D; Zhu G; Wu D; Wang X; Chen Y; Du Y; Song W; Ma Z; Authement C; Saha D; Hsieh JT; He D
Int J Radiat Oncol Biol Phys; 2014 Nov; 90(4):942-51. PubMed ID: 25585786
[TBL] [Abstract][Full Text] [Related]
6. NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2α.
Gregg JL; Turner RM; Chang G; Joshi D; Zhan Y; Chen L; Maranchie JK
Cancer Res; 2014 Jul; 74(13):3501-3511. PubMed ID: 24755467
[TBL] [Abstract][Full Text] [Related]
7. Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status.
Chen Y; Sun Y; Rao Q; Xu H; Li L; Chang C
Oncotarget; 2015 Oct; 6(31):31203-15. PubMed ID: 26304926
[TBL] [Abstract][Full Text] [Related]
8. Prolyl Hydroxylase 3 Knockdown Accelerates
Zacharias NM; Wang L; Maity T; Li L; Millward SW; Karam JA; Wood CG; Navai N
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33799686
[TBL] [Abstract][Full Text] [Related]
9. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
10. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
11. Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Walter KM; Schönenberger MJ; Trötzmüller M; Horn M; Elsässer HP; Moser AB; Lucas MS; Schwarz T; Gerber PA; Faust PL; Moch H; Köfeler HC; Krek W; Kovacs WJ
Cell Metab; 2014 Nov; 20(5):882-897. PubMed ID: 25440060
[TBL] [Abstract][Full Text] [Related]
12. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis.
Liu XD; Yao J; Tripathi DN; Ding Z; Xu Y; Sun M; Zhang J; Bai S; German P; Hoang A; Zhou L; Jonasch D; Zhang X; Conti CJ; Efstathiou E; Tannir NM; Eissa NT; Mills GB; Walker CL; Jonasch E
Oncogene; 2015 May; 34(19):2450-60. PubMed ID: 24998849
[TBL] [Abstract][Full Text] [Related]
13. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.
Liu MY; Poellinger L; Walker CL
Cancer Res; 2003 May; 63(10):2675-80. PubMed ID: 12750296
[TBL] [Abstract][Full Text] [Related]
14. CD70-Targeted Micelles Enhance HIF2α siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells.
Trac N; Oh HS; Jones LI; Caliliw R; Ohtake S; Shuch B; Chung EJ
Molecules; 2022 Dec; 27(23):. PubMed ID: 36500549
[TBL] [Abstract][Full Text] [Related]
15. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
Blancher C; Moore JW; Robertson N; Harris AL
Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
[TBL] [Abstract][Full Text] [Related]
16. Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity.
Bouthelier A; Meléndez-Rodríguez F; Urrutia AA; Aragonés J
Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33321829
[TBL] [Abstract][Full Text] [Related]
17. Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas enhances HIF2α activity.
Mathew LK; Lee SS; Skuli N; Rao S; Keith B; Nathanson KL; Lal P; Simon MC
Cancer Discov; 2014 Jan; 4(1):53-60. PubMed ID: 24189146
[TBL] [Abstract][Full Text] [Related]
18. Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation.
Nayak BK; Feliers D; Sudarshan S; Friedrichs WE; Day RT; New DD; Fitzgerald JP; Eid A; Denapoli T; Parekh DJ; Gorin Y; Block K
Oncogene; 2013 Jun; 32(26):3147-55. PubMed ID: 22869144
[TBL] [Abstract][Full Text] [Related]
19. Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma.
Chen K; Zeng J; Sun Y; Ouyang W; Yu G; Zhou H; Zhang Y; Yao W; Xiao W; Hu J; Xing J; Xiao K; Wu L; Chen Z; Ye Z; Xu H
Cancer Commun (Lond); 2021 Apr; 41(4):316-332. PubMed ID: 33591636
[TBL] [Abstract][Full Text] [Related]
20. HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.
Qiu B; Ackerman D; Sanchez DJ; Li B; Ochocki JD; Grazioli A; Bobrovnikova-Marjon E; Diehl JA; Keith B; Simon MC
Cancer Discov; 2015 Jun; 5(6):652-67. PubMed ID: 25829424
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
