BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

361 related articles for article (PubMed ID: 23103595)

  • 1. Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG.
    Gillie DJ; Novick SJ; Donovan BT; Payne LA; Townsend C
    J Pharmacol Toxicol Methods; 2013; 67(1):33-44. PubMed ID: 23103595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp.
    Haraguchi Y; Ohtsuki A; Oka T; Shimizu T
    BMC Pharmacol Toxicol; 2015 Dec; 16():39. PubMed ID: 26671227
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks HT.
    Bridgland-Taylor MH; Hargreaves AC; Easter A; Orme A; Henthorn DC; Ding M; Davis AM; Small BG; Heapy CG; Abi-Gerges N; Persson F; Jacobson I; Sullivan M; Albertson N; Hammond TG; Sullivan E; Valentin JP; Pollard CE
    J Pharmacol Toxicol Methods; 2006; 54(2):189-99. PubMed ID: 16563806
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of a hERG screen using the IonWorks HT: comparison to a hERG rubidium efflux screen.
    Sorota S; Zhang XS; Margulis M; Tucker K; Priestley T
    Assay Drug Dev Technol; 2005 Feb; 3(1):47-57. PubMed ID: 15798395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.
    Schmalhofer WA; Swensen AM; Thomas BS; Felix JP; Haedo RJ; Solly K; Kiss L; Kaczorowski GJ; Garcia ML
    Assay Drug Dev Technol; 2010 Dec; 8(6):714-26. PubMed ID: 21158686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of human Ether-à-go-go related gene screening assays based on IonWorks Quattro and thallium flux.
    Bridal TR; Margulis M; Wang X; Donio M; Sorota S
    Assay Drug Dev Technol; 2010 Dec; 8(6):755-65. PubMed ID: 20658944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.
    Zeng H; Penniman JR; Kinose F; Kim D; Trepakova ES; Malik MG; Dech SJ; Balasubramanian B; Salata JJ
    Assay Drug Dev Technol; 2008 Apr; 6(2):235-41. PubMed ID: 18471077
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.
    Guo L; Guthrie H
    J Pharmacol Toxicol Methods; 2005; 52(1):123-35. PubMed ID: 15936217
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Halide ion effects on human Ether-à-go-go related gene potassium channel properties.
    Zeng H; Balasubramanian B; Penniman JR; Kinose F; Salata JJ; Lagrutta A
    Assay Drug Dev Technol; 2013; 11(9-10):544-50. PubMed ID: 24147984
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.
    Donovan BT; Bakshi T; Galbraith SE; Nixon CJ; Payne LA; Martens SF
    J Pharmacol Toxicol Methods; 2011; 64(3):269-76. PubMed ID: 21996251
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment.
    Di Veroli GY; Davies MR; Zhang H; Abi-Gerges N; Boyett MR
    Am J Physiol Heart Circ Physiol; 2013 Jan; 304(1):H104-17. PubMed ID: 23103500
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IonFlux: a microfluidic patch clamp system evaluated with human Ether-à-go-go related gene channel physiology and pharmacology.
    Golden AP; Li N; Chen Q; Lee T; Nevill T; Cao X; Johnson J; Erdemli G; Ionescu-Zanetti C; Urban L; Holmqvist M
    Assay Drug Dev Technol; 2011 Dec; 9(6):608-19. PubMed ID: 21561375
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide.
    Milnes JT; Witchel HJ; Leaney JL; Leishman DJ; Hancox JC
    J Pharmacol Toxicol Methods; 2010; 61(2):178-91. PubMed ID: 20172036
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Observations on conducting whole-cell patch clamping of the hERG cardiac K
    Kang J; Luo Y; Searles M; Rampe D
    J Appl Toxicol; 2017 Apr; 37(4):445-453. PubMed ID: 27553911
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels.
    Zou B; Yu H; Babcock JJ; Chanda P; Bader JS; McManus OB; Li M
    Assay Drug Dev Technol; 2010 Dec; 8(6):743-54. PubMed ID: 21158688
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessing hERG channel inhibition using PatchXpress.
    Ly JQ; Shyy G; Misner DL
    Clin Lab Med; 2007 Mar; 27(1):201-8. PubMed ID: 17416313
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative evaluation of hERG potassium channel blockade by antipsychotics.
    Silvestre JS; Prous JR
    Methods Find Exp Clin Pharmacol; 2007 Sep; 29(7):457-65. PubMed ID: 17982510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dimethyl sulfoxide effects on hERG channels expressed in HEK293 cells.
    Du X; Lu D; Daharsh ED; Yao A; Dewoody R; Yao JA
    J Pharmacol Toxicol Methods; 2006; 54(2):164-72. PubMed ID: 16782359
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity.
    Yunomae K; Ichisaki S; Matsuo J; Nagayama S; Fukuzaki K; Nagata R; Kito G
    J Appl Toxicol; 2007; 27(1):78-85. PubMed ID: 17146843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds.
    Tao H; Santa Ana D; Guia A; Huang M; Ligutti J; Walker G; Sithiphong K; Chan F; Guoliang T; Zozulya Z; Saya S; Phimmachack R; Sie C; Yuan J; Wu L; Xu J; Ghetti A
    Assay Drug Dev Technol; 2004 Oct; 2(5):497-506. PubMed ID: 15671647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.