BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 23105109)

  • 1. Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.
    Hayes SD; Liu H; MacDonald E; Sanderson CM; Coulson JM; Clague MJ; Urbé S
    J Biol Chem; 2012 Dec; 287(51):43007-18. PubMed ID: 23105109
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.
    Pauli EK; Chan YK; Davis ME; Gableske S; Wang MK; Feister KF; Gack MU
    Sci Signal; 2014 Jan; 7(307):ra3. PubMed ID: 24399297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. USP15 antagonizes CRL4
    Nguyen TV
    Proc Natl Acad Sci U S A; 2021 Oct; 118(40):. PubMed ID: 34583995
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.
    Begum N; Hockman S; Manganiello VC
    J Biol Chem; 2011 Jul; 286(29):26238-49. PubMed ID: 21632535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).
    Hong SW; Jin DH; Shin JS; Moon JH; Na YS; Jung KA; Kim SM; Kim JC; Kim KP; Hong YS; Lee JL; Choi EK; Lee JS; Kim TW
    J Biol Chem; 2012 Jul; 287(28):24017-25. PubMed ID: 22628551
    [TBL] [Abstract][Full Text] [Related]  

  • 6. USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma.
    Eichhorn PJ; Rodón L; Gonzàlez-Juncà A; Dirac A; Gili M; Martínez-Sáez E; Aura C; Barba I; Peg V; Prat A; Cuartas I; Jimenez J; García-Dorado D; Sahuquillo J; Bernards R; Baselga J; Seoane J
    Nat Med; 2012 Feb; 18(3):429-35. PubMed ID: 22344298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases.
    Chou CK; Chang YT; Korinek M; Chen YT; Yang YT; Leu S; Lin IL; Tang CJ; Chiu CC
    Int J Mol Sci; 2017 Feb; 18(3):. PubMed ID: 28245560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP.
    Matheny SA; Chen C; Kortum RL; Razidlo GL; Lewis RE; White MA
    Nature; 2004 Jan; 427(6971):256-60. PubMed ID: 14724641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself.
    Wada K; Kamitani T
    Biochem Biophys Res Commun; 2006 Mar; 342(1):253-8. PubMed ID: 16472766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.
    Chan W; Tian R; Lee YF; Sit ST; Lim L; Manser E
    J Biol Chem; 2009 Mar; 284(12):8185-94. PubMed ID: 19144635
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural Basis of the Recruitment of Ubiquitin-specific Protease USP15 by Spliceosome Recycling Factor SART3.
    Zhang Q; Harding R; Hou F; Dong A; Walker JR; Bteich J; Tong Y
    J Biol Chem; 2016 Aug; 291(33):17283-92. PubMed ID: 27255711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1.
    Hetfeld BK; Helfrich A; Kapelari B; Scheel H; Hofmann K; Guterman A; Glickman M; Schade R; Kloetzel PM; Dubiel W
    Curr Biol; 2005 Jul; 15(13):1217-21. PubMed ID: 16005295
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
    Teyra J; Singer AU; Schmitges FW; Jaynes P; Kit Leng Lui S; Polyak MJ; Fodil N; Krieger JR; Tong J; Schwerdtfeger C; Brasher BB; Ceccarelli DFJ; Moffat J; Sicheri F; Moran MF; Gros P; Eichhorn PJA; Lenter M; Boehmelt G; Sidhu SS
    Structure; 2019 Apr; 27(4):590-605.e5. PubMed ID: 30713027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
    Kim EJ; Juhnn YS
    J Biol Chem; 2015 Apr; 290(15):9604-13. PubMed ID: 25713071
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.
    Xie Y; Avello M; Schirle M; McWhinnie E; Feng Y; Bric-Furlong E; Wilson C; Nathans R; Zhang J; Kirschner MW; Huang SM; Cong F
    J Biol Chem; 2013 Feb; 288(5):2976-85. PubMed ID: 23184937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BRCA1-associated protein induced proliferation and migration of gastric cancer cells through MAPK pathway.
    Wei X; Liu X; Liu H; He X; Zhuang H; Tang Y; Wang B
    Surg Oncol; 2020 Dec; 35():191-199. PubMed ID: 32890957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of ubiquitin-proteasome system-mediated Tip110 protein degradation by USP15.
    Timani KA; Liu Y; Suvannasankha A; He JJ
    Int J Biochem Cell Biol; 2014 Sep; 54():10-9. PubMed ID: 24984263
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein.
    Du JX; Hagos EG; Nandan MO; Bialkowska AB; Yu B; Yang VW
    J Biol Chem; 2011 Nov; 286(46):40354-64. PubMed ID: 21953463
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.
    Kotani Y; Morito D; Sakata K; Ainuki S; Sugihara M; Hatta T; Iemura SI; Takashima S; Natsume T; Nagata K
    Sci Rep; 2017 Mar; 7():44293. PubMed ID: 28276505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.