170 related articles for article (PubMed ID: 23110439)
1. Highly predictive ligand-based pharmacophore and homology models of ABHD6.
Bowman AL; Makriyannis A
Chem Biol Drug Des; 2013 Mar; 81(3):382-8. PubMed ID: 23110439
[TBL] [Abstract][Full Text] [Related]
2. Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors.
Kaczor AA; Targowska-Duda KM; Patel JZ; Laitinen T; Parkkari T; Adams Y; Nevalainen TJ; Poso A
J Mol Model; 2015 Oct; 21(10):250. PubMed ID: 26350245
[TBL] [Abstract][Full Text] [Related]
3. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6).
Hsu KL; Tsuboi K; Chang JW; Whitby LR; Speers AE; Pugh H; Cravatt BF
J Med Chem; 2013 Nov; 56(21):8270-9. PubMed ID: 24152295
[TBL] [Abstract][Full Text] [Related]
4. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors.
Patel JZ; Nevalainen TJ; Savinainen JR; Adams Y; Laitinen T; Runyon RS; Vaara M; Ahenkorah S; Kaczor AA; Navia-Paldanius D; Gynther M; Aaltonen N; Joharapurkar AA; Jain MR; Haka AS; Maxfield FR; Laitinen JT; Parkkari T
ChemMedChem; 2015 Feb; 10(2):253-65. PubMed ID: 25504894
[TBL] [Abstract][Full Text] [Related]
5. Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.
Patel JZ; van Bruchem J; Laitinen T; Kaczor AA; Navia-Paldanius D; Parkkari T; Savinainen JR; Laitinen JT; Nevalainen TJ
Bioorg Med Chem; 2015 Oct; 23(19):6335-45. PubMed ID: 26344596
[TBL] [Abstract][Full Text] [Related]
6. Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study.
Jha V; Biagi M; Spinelli V; Di Stefano M; Macchia M; Minutolo F; Granchi C; Poli G; Tuccinardi T
Molecules; 2020 Dec; 26(1):. PubMed ID: 33375358
[TBL] [Abstract][Full Text] [Related]
7. Monoacylglycerol signalling and ABHD6 in health and disease.
Poursharifi P; Madiraju SRM; Prentki M
Diabetes Obes Metab; 2017 Sep; 19 Suppl 1():76-89. PubMed ID: 28880480
[TBL] [Abstract][Full Text] [Related]
8. Watermelon: setup and validation of an
Di Stefano M; Galati S; Piazza L; Gado F; Granchi C; Macchia M; Giordano A; Tuccinardi T; Poli G
J Enzyme Inhib Med Chem; 2024 Dec; 39(1):2356179. PubMed ID: 38864179
[TBL] [Abstract][Full Text] [Related]
9. Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12).
Parkkari T; Haavikko R; Laitinen T; Navia-Paldanius D; Rytilahti R; Vaara M; Lehtonen M; Alakurtti S; Yli-Kauhaluoma J; Nevalainen T; Savinainen JR; Laitinen JT
PLoS One; 2014; 9(5):e98286. PubMed ID: 24879289
[TBL] [Abstract][Full Text] [Related]
10. The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Thomas G; Betters JL; Lord CC; Brown AL; Marshall S; Ferguson D; Sawyer J; Davis MA; Melchior JT; Blume LC; Howlett AC; Ivanova PT; Milne SB; Myers DS; Mrak I; Leber V; Heier C; Taschler U; Blankman JL; Cravatt BF; Lee RG; Crooke RM; Graham MJ; Zimmermann R; Brown HA; Brown JM
Cell Rep; 2013 Oct; 5(2):508-20. PubMed ID: 24095738
[TBL] [Abstract][Full Text] [Related]
11. Therapeutic potential of targeting α/β-Hydrolase domain-containing 6 (ABHD6).
Deng H; Li W
Eur J Med Chem; 2020 Jul; 198():112353. PubMed ID: 32371333
[TBL] [Abstract][Full Text] [Related]
12. Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.
Aghazadeh Tabrizi M; Baraldi PG; Baraldi S; Ruggiero E; De Stefano L; Rizzolio F; Di Cesare Mannelli L; Ghelardini C; Chicca A; Lapillo M; Gertsch J; Manera C; Macchia M; Martinelli A; Granchi C; Minutolo F; Tuccinardi T
J Med Chem; 2018 Feb; 61(3):1340-1354. PubMed ID: 29309142
[TBL] [Abstract][Full Text] [Related]
13. Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis.
Wen J; Ribeiro R; Tanaka M; Zhang Y
Neuropharmacology; 2015 Dec; 99():196-209. PubMed ID: 26189763
[TBL] [Abstract][Full Text] [Related]
14. Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors.
Afzal O; Kumar S; Kumar R; Firoz A; Jaggi M; Bawa S
Bioorg Med Chem Lett; 2014 Aug; 24(16):3986-96. PubMed ID: 25011912
[TBL] [Abstract][Full Text] [Related]
15. The α/β-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids.
Bottemanne P; Paquot A; Ameraoui H; Alhouayek M; Muccioli GG
FASEB J; 2019 Jun; 33(6):7635-7646. PubMed ID: 30896979
[TBL] [Abstract][Full Text] [Related]
16. Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors.
Malamas MS; Lamani M; Farah SI; Mohammad KA; Miyabe CY; Rajarshi G; Wu S; Zvonok N; Chandrashekhar H; Wood J; Makriyannis A
ChemMedChem; 2023 Nov; 18(21):e202100406. PubMed ID: 34486233
[TBL] [Abstract][Full Text] [Related]
17. Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis.
Manterola A; Bernal-Chico A; Cipriani R; Ruiz A; Pérez-Samartín A; Moreno-Rodríguez M; Hsu KL; Cravatt BF; Brown JM; Rodríguez-Puertas R; Matute C; Mato S
Neuropharmacology; 2018 Oct; 141():181-191. PubMed ID: 30171986
[TBL] [Abstract][Full Text] [Related]
18. Ligand and structure-based approaches for the identification of SIRT1 activators.
Vyas VK; Goel A; Ghate M; Patel P
Chem Biol Interact; 2015 Feb; 228():9-17. PubMed ID: 25595223
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis, and Evaluation of
Chen Z; Mori W; Fu H; Schafroth MA; Hatori A; Shao T; Zhang G; Van RS; Zhang Y; Hu K; Fujinaga M; Wang L; Belov V; Ogasawara D; Giffenig P; Deng X; Rong J; Yu Q; Zhang X; Papisov MI; Shao Y; Collier TL; Ma JA; Cravatt BF; Josephson L; Zhang MR; Liang SH
J Med Chem; 2019 Oct; 62(19):8866-8872. PubMed ID: 31518130
[TBL] [Abstract][Full Text] [Related]
20. WWL70 attenuates PGE
Tanaka M; Moran S; Wen J; Affram K; Chen T; Symes AJ; Zhang Y
J Neuroinflammation; 2017 Jan; 14(1):7. PubMed ID: 28086912
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
