172 related articles for article (PubMed ID: 23116399)
1. Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase.
Pinheiro MP; Emery Fda S; Nonato MC
Curr Pharm Des; 2013; 19(14):2615-27. PubMed ID: 23116399
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain.
Pinheiro MP; Iulek J; Cristina Nonato M
Biochem Biophys Res Commun; 2008 May; 369(3):812-7. PubMed ID: 18302934
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of dihydroorotate dehydrogenase from Leishmania major.
Cordeiro AT; Feliciano PR; Pinheiro MP; Nonato MC
Biochimie; 2012 Aug; 94(8):1739-48. PubMed ID: 22542640
[TBL] [Abstract][Full Text] [Related]
4. Recent developments in the medicinal chemistry and therapeutic potential of dihydroorotate dehydrogenase (DHODH) inhibitors.
Vyas VK; Ghate M
Mini Rev Med Chem; 2011 Oct; 11(12):1039-55. PubMed ID: 21861807
[TBL] [Abstract][Full Text] [Related]
5. The dihydroorotate dehydrogenases: Past and present.
Reis RAG; Calil FA; Feliciano PR; Pinheiro MP; Nonato MC
Arch Biochem Biophys; 2017 Oct; 632():175-191. PubMed ID: 28666740
[TBL] [Abstract][Full Text] [Related]
6. Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis.
Reis RA; Lorenzato E; Silva VC; Nonato MC
Acta Crystallogr F Struct Biol Commun; 2015 May; 71(Pt 5):547-52. PubMed ID: 25945707
[TBL] [Abstract][Full Text] [Related]
7. Dihydroorotate dehydrogenase inhibitors in anti-infective drug research.
Boschi D; Pippione AC; Sainas S; Lolli ML
Eur J Med Chem; 2019 Dec; 183():111681. PubMed ID: 31557612
[TBL] [Abstract][Full Text] [Related]
8. Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.
de Mori RM; Aleixo MAA; Zapata LCC; Calil FA; Emery FS; Nonato MC
FEBS J; 2021 Feb; 288(3):930-944. PubMed ID: 32428996
[TBL] [Abstract][Full Text] [Related]
9. Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery.
Cheleski J; Rocha JR; Pinheiro MP; Wiggers HJ; da Silva AB; Nonato MC; Montanari CA
Eur J Med Chem; 2010 Dec; 45(12):5899-909. PubMed ID: 20965617
[TBL] [Abstract][Full Text] [Related]
10. Cysteine peptidase inhibitors in trypanosomatid parasites.
Lima AP; Reis FC; Costa TF
Curr Med Chem; 2013; 20(25):3152-73. PubMed ID: 23514421
[TBL] [Abstract][Full Text] [Related]
11. Effects of dihydroorotate dehydrogenase (DHODH) inhibitors on the growth of Theileria equi and Babesia caballi in vitro.
Kamyingkird K; Cao S; Tuvshintulga B; Salama A; Mousa AA; Efstratiou A; Nishikawa Y; Yokoyama N; Igarashi I; Xuan X
Exp Parasitol; 2017 May; 176():59-65. PubMed ID: 28286324
[TBL] [Abstract][Full Text] [Related]
12. Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy.
Okesli A; Khosla C; Bassik MC
Curr Opin Biotechnol; 2017 Dec; 48():127-134. PubMed ID: 28458037
[TBL] [Abstract][Full Text] [Related]
13. Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer.
Madak JT; Bankhead A; Cuthbertson CR; Showalter HD; Neamati N
Pharmacol Ther; 2019 Mar; 195():111-131. PubMed ID: 30347213
[TBL] [Abstract][Full Text] [Related]
14. The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions.
Annoura T; Nara T; Makiuchi T; Hashimoto T; Aoki T
J Mol Evol; 2005 Jan; 60(1):113-27. PubMed ID: 15696374
[TBL] [Abstract][Full Text] [Related]
15. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies.
Arakaki TL; Buckner FS; Gillespie JR; Malmquist NA; Phillips MA; Kalyuzhniy O; Luft JR; Detitta GT; Verlinde CL; Van Voorhis WC; Hol WG; Merritt EA
Mol Microbiol; 2008 Apr; 68(1):37-50. PubMed ID: 18312275
[TBL] [Abstract][Full Text] [Related]
16. Parasite prolyl oligopeptidases and the challenge of designing chemotherapeuticals for Chagas disease, leishmaniasis and African trypanosomiasis.
Bastos IM; Motta FN; Grellier P; Santana JM
Curr Med Chem; 2013; 20(25):3103-15. PubMed ID: 23514419
[TBL] [Abstract][Full Text] [Related]
17. Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
Chibli LA; Schmidt TJ; Nonato MC; Calil FA; Da Costa FB
Eur J Med Chem; 2018 Sep; 157():852-866. PubMed ID: 30145372
[TBL] [Abstract][Full Text] [Related]
18. Structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans.
Liu Y; Gao ZQ; Liu CP; Xu JH; Li LF; Ji CN; Su XD; Dong YH
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Feb; 67(Pt 2):182-7. PubMed ID: 21301083
[TBL] [Abstract][Full Text] [Related]
19. High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
Baldwin J; Michnoff CH; Malmquist NA; White J; Roth MG; Rathod PK; Phillips MA
J Biol Chem; 2005 Jun; 280(23):21847-53. PubMed ID: 15795226
[TBL] [Abstract][Full Text] [Related]
20. A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode.
Zeng T; Zuo Z; Luo Y; Zhao Y; Yu Y; Chen Q
FEBS Open Bio; 2019 Aug; 9(8):1348-1354. PubMed ID: 31087527
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
