These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Cytotoxic 3,6-bis((imidazolidinone)imino)acridines: synthesis, DNA binding and molecular modeling. Janovec L; Kožurková M; Sabolová D; Ungvarský J; Paulíková H; Plšíková J; Vantová Z; Imrich J Bioorg Med Chem; 2011 Mar; 19(5):1790-801. PubMed ID: 21315610 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents. Gao C; Li B; Zhang B; Sun Q; Li L; Li X; Chen C; Tan C; Liu H; Jiang Y Bioorg Med Chem; 2015 Apr; 23(8):1800-7. PubMed ID: 25778766 [TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents. Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S J Med Chem; 2003 Jul; 46(14):3109-15. PubMed ID: 12825949 [TBL] [Abstract][Full Text] [Related]
6. 4-Hydroxymethyl-3-aminoacridine derivatives as a new family of anticancer agents. Charmantray F; Demeunynck M; Carrez D; Croisy A; Lansiaux A; Bailly C; Colson P J Med Chem; 2003 Mar; 46(6):967-77. PubMed ID: 12620073 [TBL] [Abstract][Full Text] [Related]
7. Isoquino[4,5-bc]acridines: design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability. Yang P; Yang Q; Qian X; Tong L; Li X J Photochem Photobiol B; 2006 Sep; 84(3):221-6. PubMed ID: 16714120 [TBL] [Abstract][Full Text] [Related]
8. Synthesis, spectroscopic, physicochemical and structural characterization of tetrandrine-based macrocycles functionalized with acridine and anthracene groups: DNA binding and anti-proliferative activity. Calvillo-Páez V; Sotelo-Mundo RR; Leyva-Peralta M; Gálvez-Ruiz JC; Corona-Martínez D; Moreno-Corral R; Escobar-Picos R; Höpfl H; Juárez-Sánchez O; Lara KO Chem Biol Interact; 2018 Apr; 286():34-44. PubMed ID: 29476729 [TBL] [Abstract][Full Text] [Related]
9. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome. Vispé S; Vandenberghe I; Robin M; Annereau JP; Créancier L; Pique V; Galy JP; Kruczynski A; Barret JM; Bailly C Biochem Pharmacol; 2007 Jun; 73(12):1863-72. PubMed ID: 17391647 [TBL] [Abstract][Full Text] [Related]
10. Influence of polyamine architecture on the transport and topoisomerase II inhibitory properties of polyamine DNA-intercalator conjugates. Wang L; Price HL; Juusola J; Kline M; Phanstiel O J Med Chem; 2001 Oct; 44(22):3682-91. PubMed ID: 11606133 [TBL] [Abstract][Full Text] [Related]
11. Bisintercalating threading diacridines: relationships between DNA binding, cytotoxicity, and cell cycle arrest. Wakelin LP; Bu X; Eleftheriou A; Parmar A; Hayek C; Stewart BW J Med Chem; 2003 Dec; 46(26):5790-802. PubMed ID: 14667232 [TBL] [Abstract][Full Text] [Related]
12. Cytotoxic activity of acridin-3,6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR. Vantová Z; Paulíková H; Sabolová D; Kozurková M; Suchánová M; Janovec L; Kristian P; Imrich J Int J Biol Macromol; 2009 Aug; 45(2):174-80. PubMed ID: 19414028 [TBL] [Abstract][Full Text] [Related]
13. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine. Guddneppanavar R; Saluta G; Kucera GL; Bierbach U J Med Chem; 2006 Jun; 49(11):3204-14. PubMed ID: 16722638 [TBL] [Abstract][Full Text] [Related]
14. New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds. Salem OM; Vilková M; Janočková J; Jendželovský R; Fedoročko P; Žilecká E; Kašpárková J; Brabec V; Imrich J; Kožurková M Int J Biol Macromol; 2016 May; 86():690-700. PubMed ID: 26861825 [TBL] [Abstract][Full Text] [Related]
15. Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines. Braña MF; Casarrubios L; Domínguez G; Fernández C; Pérez JM; Quiroga AG; Navarro-Ranninger C; de Pascual-Teresa B Eur J Med Chem; 2002 Apr; 37(4):301-13. PubMed ID: 11960665 [TBL] [Abstract][Full Text] [Related]
16. Correlation between DNA/HSA-interactions and antimalarial activity of acridine derivatives: Proposing a possible mechanism of action. de M Silva M; Macedo TS; Teixeira HMP; Moreira DRM; Soares MBP; da C Pereira AL; de L Serafim V; Mendonça-Júnior FJB; do Carmo A de Lima M; de Moura RO; da Silva-Júnior EF; de Araújo-Júnior JX; de A Dantas MD; de O O Nascimento E; Maciel TMS; de Aquino TM; Figueiredo IM; Santos JCC J Photochem Photobiol B; 2018 Dec; 189():165-175. PubMed ID: 30366283 [TBL] [Abstract][Full Text] [Related]
17. 1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation. Antonini I; Polucci P; Jenkins TC; Kelland LR; Menta E; Pescalli N; Stefanska B; Mazerski J; Martelli S J Med Chem; 1997 Nov; 40(23):3749-55. PubMed ID: 9371240 [TBL] [Abstract][Full Text] [Related]
18. 2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents. Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S J Med Chem; 2002 Jan; 45(3):696-702. PubMed ID: 11806721 [TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of threading intercalators to target DNA. Howell LA; Gulam R; Mueller A; O'Connell MA; Searcey M Bioorg Med Chem Lett; 2010 Dec; 20(23):6956-9. PubMed ID: 20980148 [TBL] [Abstract][Full Text] [Related]