223 related articles for article (PubMed ID: 23124202)
1. The human W42R γD-crystallin mutant structure provides a link between congenital and age-related cataracts.
Ji F; Jung J; Koharudin LM; Gronenborn AM
J Biol Chem; 2013 Jan; 288(1):99-109. PubMed ID: 23124202
[TBL] [Abstract][Full Text] [Related]
2. Molecular Mechanism of Aggregation of the Cataract-Related γD-Crystallin W42R Variant from Multiscale Atomistic Simulations.
Wong EK; Prytkova V; Freites JA; Butts CT; Tobias DJ
Biochemistry; 2019 Sep; 58(35):3691-3699. PubMed ID: 31393108
[TBL] [Abstract][Full Text] [Related]
3. The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.
Evans P; Wyatt K; Wistow GJ; Bateman OA; Wallace BA; Slingsby C
J Mol Biol; 2004 Oct; 343(2):435-44. PubMed ID: 15451671
[TBL] [Abstract][Full Text] [Related]
4. Thermodynamic Stability of Human γD-Crystallin Mutants Using Alchemical Free-Energy Calculations.
Aguayo-Ortiz R; González-Navejas A; Palomino-Vizcaino G; Rodriguez-Meza O; Costas M; Quintanar L; Dominguez L
J Phys Chem B; 2019 Jul; 123(27):5671-5677. PubMed ID: 31199646
[TBL] [Abstract][Full Text] [Related]
5. Structural and biochemical characterization of the childhood cataract-associated R76S mutant of human γD-crystallin.
Ji F; Jung J; Gronenborn AM
Biochemistry; 2012 Mar; 51(12):2588-96. PubMed ID: 22394327
[TBL] [Abstract][Full Text] [Related]
6. GammaD-crystallin associated protein aggregation and lens fiber cell denucleation.
Wang K; Cheng C; Li L; Liu H; Huang Q; Xia CH; Yao K; Sun P; Horwitz J; Gong X
Invest Ophthalmol Vis Sci; 2007 Aug; 48(8):3719-28. PubMed ID: 17652744
[TBL] [Abstract][Full Text] [Related]
7. The importance of the fourth Greek key motif of human γD-crystallin in maintaining lens transparency-the tale told by the tail.
Vendra V; Thangapandian M
Mol Vis; 2024; 30():37-48. PubMed ID: 38586607
[TBL] [Abstract][Full Text] [Related]
8. High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract.
Basak A; Bateman O; Slingsby C; Pande A; Asherie N; Ogun O; Benedek GB; Pande J
J Mol Biol; 2003 May; 328(5):1137-47. PubMed ID: 12729747
[TBL] [Abstract][Full Text] [Related]
9. Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins.
Mishra S; Stein RA; McHaourab HS
FEBS Lett; 2012 Feb; 586(4):330-6. PubMed ID: 22289178
[TBL] [Abstract][Full Text] [Related]
10. A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract.
Zhang LY; Gong B; Tong JP; Fan DS; Chiang SW; Lou D; Lam DS; Yam GH; Pang CP
Mol Vis; 2009 Aug; 15():1521-9. PubMed ID: 19668596
[TBL] [Abstract][Full Text] [Related]
11. A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.
Whitley MJ; Xi Z; Bartko JC; Jensen MR; Blackledge M; Gronenborn AM
Biophys J; 2017 Mar; 112(6):1135-1146. PubMed ID: 28355541
[TBL] [Abstract][Full Text] [Related]
12. The G18V CRYGS mutation associated with human cataracts increases gammaS-crystallin sensitivity to thermal and chemical stress.
Ma Z; Piszczek G; Wingfield PT; Sergeev YV; Hejtmancik JF
Biochemistry; 2009 Aug; 48(30):7334-41. PubMed ID: 19558189
[TBL] [Abstract][Full Text] [Related]
13. Computer construction and analysis of protein models of the mutant gammaD-crystallin gene.
Yao K; Sun ZH; Shentu XC; Wang KJ; Tan J
Chin Med J (Engl); 2005 May; 118(9):738-41. PubMed ID: 15899135
[TBL] [Abstract][Full Text] [Related]
14. Hydrophobic core mutations associated with cataract development in mice destabilize human gammaD-crystallin.
Moreau KL; King J
J Biol Chem; 2009 Nov; 284(48):33285-95. PubMed ID: 19758984
[TBL] [Abstract][Full Text] [Related]
15. A novel mutation in γD-crystallin associated with autosomal dominant congenital cataract in a Chinese family.
Wang L; Chen X; Lu Y; Wu J; Yang B; Sun X
Mol Vis; 2011 Mar; 17():804-9. PubMed ID: 21527994
[TBL] [Abstract][Full Text] [Related]
16. An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.
Serebryany E; Woodard JC; Adkar BV; Shabab M; King JA; Shakhnovich EI
J Biol Chem; 2016 Sep; 291(36):19172-83. PubMed ID: 27417136
[TBL] [Abstract][Full Text] [Related]
17. Cataract-causing defect of a mutant γ-crystallin proceeds through an aggregation pathway which bypasses recognition by the α-crystallin chaperone.
Moreau KL; King JA
PLoS One; 2012; 7(5):e37256. PubMed ID: 22655036
[TBL] [Abstract][Full Text] [Related]
18. Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.
Boatz JC; Whitley MJ; Li M; Gronenborn AM; van der Wel PCA
Nat Commun; 2017 May; 8():15137. PubMed ID: 28474685
[TBL] [Abstract][Full Text] [Related]
19. The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes.
Jung J; Byeon IJ; Wang Y; King J; Gronenborn AM
Biochemistry; 2009 Mar; 48(12):2597-609. PubMed ID: 19216553
[TBL] [Abstract][Full Text] [Related]
20. Wild-type human γD-crystallin promotes aggregation of its oxidation-mimicking, misfolding-prone W42Q mutant.
Serebryany E; King JA
J Biol Chem; 2015 May; 290(18):11491-503. PubMed ID: 25787081
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]