These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 23129805)

  • 1. Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission.
    van der Hoeven D; Cho KJ; Ma X; Chigurupati S; Parton RG; Hancock JF
    Mol Cell Biol; 2013 Jan; 33(2):237-51. PubMed ID: 23129805
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of K-Ras plasma membrane localization.
    Cho KJ; van der Hoeven D; Hancock JF
    Enzymes; 2013; 33 Pt A():249-65. PubMed ID: 25033808
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane.
    Cho KJ; van der Hoeven D; Zhou Y; Maekawa M; Ma X; Chen W; Fairn GD; Hancock JF
    Mol Cell Biol; 2016 Jan; 36(2):363-74. PubMed ID: 26572827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An oxanthroquinone derivative that disrupts RAS plasma membrane localization inhibits cancer cell growth.
    Tan L; Cho KJ; Neupane P; Capon RJ; Hancock JF
    J Biol Chem; 2018 Aug; 293(35):13696-13706. PubMed ID: 29970615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins.
    Cho KJ; Park JH; Piggott AM; Salim AA; Gorfe AA; Parton RG; Capon RJ; Lacey E; Hancock JF
    J Biol Chem; 2012 Dec; 287(52):43573-84. PubMed ID: 23124205
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors.
    Wang P; van der Hoeven D; Ye N; Chen H; Liu Z; Ma X; Montufar-Solis D; Rehl KM; Cho KJ; Thapa S; Chen W; van der Hoeven R; Frost JA; Hancock JF; Zhou J
    Eur J Med Chem; 2021 May; 217():113381. PubMed ID: 33756124
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC.
    Alhothali M; Mathew M; Iyer G; Lawrence HR; Yang S; Chellappan S; Padmanabhan J
    Int J Mol Sci; 2019 May; 20(10):. PubMed ID: 31100813
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment.
    Gomez GA; Daniotti JL
    J Biol Chem; 2005 Oct; 280(41):34997-5010. PubMed ID: 16079139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Another surprise from Metformin: novel mechanism of action via K-Ras influences endometrial cancer response to therapy.
    Iglesias DA; Yates MS; van der Hoeven D; Rodkey TL; Zhang Q; Co NN; Burzawa J; Chigurupati S; Celestino J; Bowser J; Broaddus R; Hancock JF; Schmandt R; Lu KH
    Mol Cancer Ther; 2013 Dec; 12(12):2847-56. PubMed ID: 24077915
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas.
    Levy R; Grafi-Cohen M; Kraiem Z; Kloog Y
    Mol Cancer Ther; 2010 Aug; 9(8):2208-19. PubMed ID: 20682656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chalcones bearing a 3,4,5-trimethoxyphenyl motif are capable of selectively inhibiting oncogenic K-Ras signaling.
    Kovar SE; Fourman C; Kinstedt C; Williams B; Morris C; Cho KJ; Ketcha DM
    Bioorg Med Chem Lett; 2020 Jun; 30(11):127144. PubMed ID: 32276831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fendiline increases [Ca2+]i in Madin Darby canine kidney (MDCK) cells by releasing internal Ca2+ followed by capacitative Ca2+ entry.
    Jan CR; Tseng CJ; Chen WC
    Life Sci; 2000; 66(11):1053-62. PubMed ID: 10724452
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling.
    Woods N; Trevino J; Coppola D; Chellappan S; Yang S; Padmanabhan J
    Oncotarget; 2015 Nov; 6(34):35931-48. PubMed ID: 26440150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of pancreatic cancer growth by superoxide.
    Du J; Nelson ES; Simons AL; Olney KE; Moser JC; Schrock HE; Wagner BA; Buettner GR; Smith BJ; Teoh ML; Tsao MS; Cullen JJ
    Mol Carcinog; 2013 Jul; 52(7):555-67. PubMed ID: 22392697
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.
    de la Vega M; Burrows JF; McFarlane C; Govender U; Scott CJ; Johnston JA
    J Biol Chem; 2010 Apr; 285(16):12028-36. PubMed ID: 20147298
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Compartmentalized Ras signaling differentially contributes to phenotypic outputs.
    Aran V; Prior IA
    Cell Signal; 2013 Sep; 25(9):1748-53. PubMed ID: 23707528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells.
    Huang C; Huang C; Cheng J; Liu S; Chen I; Tsai J; Chou C; Tseng P; Jan C
    Hum Exp Toxicol; 2009 Jan; 28(1):41-8. PubMed ID: 19411560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2.
    Cho KJ; Casteel DE; Prakash P; Tan L; van der Hoeven D; Salim AA; Kim C; Capon RJ; Lacey E; Cunha SR; Gorfe AA; Hancock JF
    Mol Cell Biol; 2016 Dec; 36(24):3086-3099. PubMed ID: 27697864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oligomycins as inhibitors of K-Ras plasma membrane localisation.
    Salim AA; Tan L; Huang XC; Cho KJ; Lacey E; Hancock JF; Capon RJ
    Org Biomol Chem; 2016 Jan; 14(2):711-715. PubMed ID: 26565618
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
    Miller TE; Henkels KM; Huddleston M; Salisbury R; Hussain SM; Sasaki AT; Cho KJ
    J Cell Sci; 2019 Aug; 132(16):. PubMed ID: 31331963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.