These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 23129808)

  • 1. Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling.
    Mercan F; Lee H; Kolli S; Bennett AM
    Mol Cell Biol; 2013 Jan; 33(2):293-306. PubMed ID: 23129808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism.
    Schriever SC; Deutsch MJ; Adamski J; Roscher AA; Ensenauer R
    J Nutr Biochem; 2013 May; 24(5):824-31. PubMed ID: 22898570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.
    Hong S; Zhao B; Lombard DB; Fingar DC; Inoki K
    J Biol Chem; 2014 May; 289(19):13132-41. PubMed ID: 24652283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.
    Byfield MP; Murray JT; Backer JM
    J Biol Chem; 2005 Sep; 280(38):33076-82. PubMed ID: 16049009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway.
    Zito CI; Qin H; Blenis J; Bennett AM
    J Biol Chem; 2007 Mar; 282(10):6946-53. PubMed ID: 17229738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise.
    Moberg M; Apró W; Ekblom B; van Hall G; Holmberg HC; Blomstrand E
    Am J Physiol Cell Physiol; 2016 Jun; 310(11):C874-84. PubMed ID: 27053525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling.
    Gao S; Duan C; Gao G; Wang X; Yang H
    Int J Biochem Cell Biol; 2015 Jul; 64():25-33. PubMed ID: 25813876
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes.
    Talvas J; Obled A; Fafournoux P; Mordier S
    J Nutr; 2006 Jun; 136(6):1466-71. PubMed ID: 16702305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise.
    Apró W; Moberg M; Hamilton DL; Ekblom B; Rooyackers O; Holmberg HC; Blomstrand E
    FASEB J; 2015 Oct; 29(10):4358-73. PubMed ID: 26169935
    [TBL] [Abstract][Full Text] [Related]  

  • 11. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.
    Ben-Hur V; Denichenko P; Siegfried Z; Maimon A; Krainer A; Davidson B; Karni R
    Cell Rep; 2013 Jan; 3(1):103-15. PubMed ID: 23273915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
    Nagamori S; Wiriyasermkul P; Okuda S; Kojima N; Hari Y; Kiyonaka S; Mori Y; Tominaga H; Ohgaki R; Kanai Y
    Amino Acids; 2016 Apr; 48(4):1045-1058. PubMed ID: 26724922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Elevated protein kinase D3 (PKD3) expression supports proliferation of triple-negative breast cancer cells and contributes to mTORC1-S6K1 pathway activation.
    Huck B; Duss S; Hausser A; Olayioye MA
    J Biol Chem; 2014 Feb; 289(6):3138-47. PubMed ID: 24337579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin complex 1 (mTORC1) plays a role in Pasteurella multocida toxin (PMT)-induced protein synthesis and proliferation in Swiss 3T3 cells.
    Oubrahim H; Wong A; Wilson BA; Chock PB
    J Biol Chem; 2013 Jan; 288(4):2805-15. PubMed ID: 23223576
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.
    Lee SJ; Yang EK; Kim SG
    Mol Pharmacol; 2006 Jul; 70(1):415-25. PubMed ID: 16611854
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
    Liu L; Luo Y; Chen L; Shen T; Xu B; Chen W; Zhou H; Han X; Huang S
    J Biol Chem; 2010 Dec; 285(49):38362-73. PubMed ID: 20937815
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
    Pearce LR; Alton GR; Richter DT; Kath JC; Lingardo L; Chapman J; Hwang C; Alessi DR
    Biochem J; 2010 Oct; 431(2):245-55. PubMed ID: 20704563
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb.
    Kelleher AR; Kimball SR; Dennis MD; Schilder RJ; Jefferson LS
    Am J Physiol Endocrinol Metab; 2013 Jan; 304(2):E229-36. PubMed ID: 23193052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.
    Lang CH; Frost RA
    J Cell Physiol; 2005 Apr; 203(1):144-55. PubMed ID: 15389631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.