BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

39 related articles for article (PubMed ID: 23130825)

  • 21. Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product.
    Wu TK; Wen HY; Chang CH; Liu YT
    Org Lett; 2008 Jun; 10(12):2529-32. PubMed ID: 18494476
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The cysteine 703 to isoleucine or histidine mutation of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae generates an iridal-type triterpenoid.
    Chang CH; Chen YC; Tseng SW; Liu YT; Wen HY; Li WH; Huang CY; Ko CY; Wang TT; Wu TK
    Biochimie; 2012 Nov; 94(11):2376-81. PubMed ID: 22732192
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions.
    Wu TK; Yu MT; Liu YT; Chang CH; Wang HJ; Diau EW
    Org Lett; 2006 Mar; 8(7):1319-22. PubMed ID: 16562881
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
    Thoma R; Schulz-Gasch T; D'Arcy B; Benz J; Aebi J; Dehmlow H; Hennig M; Stihle M; Ruf A
    Nature; 2004 Nov; 432(7013):118-22. PubMed ID: 15525992
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Site-saturated mutagenesis of histidine 234 of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rearrangement reactions.
    Wu TK; Liu YT; Chang CH; Yu MT; Wang HJ
    J Am Chem Soc; 2006 May; 128(19):6414-9. PubMed ID: 16683806
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Site-directed mutagenesis and substrate compatibility to reveal the structure-function relationships of plant oxidosqualene cyclases.
    Chen K; Zhang M; Ye M; Qiao X
    Nat Prod Rep; 2021 Dec; 38(12):2261-2275. PubMed ID: 33988197
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Squalene-hopene cyclases-evolution, dynamics and catalytic scope.
    Syrén PO; Henche S; Eichler A; Nestl BM; Hauer B
    Curr Opin Struct Biol; 2016 Dec; 41():73-82. PubMed ID: 27336183
    [TBL] [Abstract][Full Text] [Related]  

  • 28. β-Amyrin biosynthesis: catalytic mechanism and substrate recognition.
    Hoshino T
    Org Biomol Chem; 2017 Apr; 15(14):2869-2891. PubMed ID: 28294269
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Catalytic mechanism and product specificity of oxidosqualene-lanosterol cyclase: a QM/MM study.
    Tian BX; Eriksson LA
    J Phys Chem B; 2012 Nov; 116(47):13857-62. PubMed ID: 23130825
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear.
    Huff MW; Telford DE
    Trends Pharmacol Sci; 2005 Jul; 26(7):335-40. PubMed ID: 15951028
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design strategies of oxidosqualene cyclase inhibitors: Targeting the sterol biosynthetic pathway.
    Rabelo VW; Romeiro NC; Abreu PA
    J Steroid Biochem Mol Biol; 2017 Jul; 171():305-317. PubMed ID: 28479228
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Enzymatic synthesis of cyclic triterpenes.
    Abe I
    Nat Prod Rep; 2007 Dec; 24(6):1311-31. PubMed ID: 18033581
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase: a chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships.
    Wu TK; Chang CH; Liu YT; Wang TT
    Chem Rec; 2008; 8(5):302-25. PubMed ID: 18956480
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Oxidosqualene cyclases in triterpenoids biosynthesis: a review].
    Chen C; Pang Y; Chen Q; Li C; Lü B
    Sheng Wu Gong Cheng Xue Bao; 2022 Feb; 38(2):443-459. PubMed ID: 35234375
    [TBL] [Abstract][Full Text] [Related]  

  • 35.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 36.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 37.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 38.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 39.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Previous]     [New Search]
    of 2.