BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 23131042)

  • 1. Evaluation of the metabolism and hepatotoxicity of xenobiotics utilizing precision-cut slices.
    Lake BG; Price RJ
    Xenobiotica; 2013 Jan; 43(1):41-53. PubMed ID: 23131042
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.
    Ioannides C
    Xenobiotica; 2013 Jan; 43(1):15-28. PubMed ID: 22742738
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.
    Ekins S; Williams JA; Murray GI; Burke MD; Marchant NC; Engeset J; Hawksworth GM
    Drug Metab Dispos; 1996 Sep; 24(9):990-5. PubMed ID: 8886609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of the intestinal toxicity and transport of xenobiotics utilizing precision-cut slices.
    Niu X; de Graaf IA; Groothuis GM
    Xenobiotica; 2013 Jan; 43(1):73-83. PubMed ID: 23106567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies.
    Morin JP; Baste JM; Gay A; Crochemore C; Corbière C; Monteil C
    Xenobiotica; 2013 Jan; 43(1):63-72. PubMed ID: 23030793
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
    Steensma A; Beamand JA; Walters DG; Price RJ; Lake BG
    Xenobiotica; 1994 Sep; 24(9):893-907. PubMed ID: 7810171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sex-dependent metabolism of xenobiotics.
    Mugford CA; Kedderis GL
    Drug Metab Rev; 1998 Aug; 30(3):441-98. PubMed ID: 9710703
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats.
    Lupp A; Danz M; Müller D
    Toxicology; 2005 Jan; 206(3):427-38. PubMed ID: 15588932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.
    Elferink MG; Olinga P; van Leeuwen EM; Bauerschmidt S; Polman J; Schoonen WG; Heisterkamp SH; Groothuis GM
    Toxicol Appl Pharmacol; 2011 May; 253(1):57-69. PubMed ID: 21420995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72 h.
    Umachandran M; Ioannides C
    Toxicology; 2006 Jul; 224(1-2):14-21. PubMed ID: 16701934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of some indole derivatives on xenobiotic metabolism and xenobiotic-induced toxicity in cultured rat liver slices.
    Renwick AB; Mistry H; Barton PT; Mallet F; Price RJ; Beamand JA; Lake BG
    Food Chem Toxicol; 1999 Jun; 37(6):609-18. PubMed ID: 10478829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alterations of the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices.
    VandenBranden M; Wrighton SA; Ekins S; Gillespie JS; Binkley SN; Ring BJ; Gadberry MG; Mullins DC; Strom SC; Jensen CB
    Drug Metab Dispos; 1998 Nov; 26(11):1063-8. PubMed ID: 9806947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days.
    Starokozhko V; Vatakuti S; Schievink B; Merema MT; Asplund A; Synnergren J; Aspegren A; Groothuis GMM
    Arch Toxicol; 2017 May; 91(5):2079-2092. PubMed ID: 27717970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
    Braeuning A; Sanna R; Huelsken J; Schwarz M
    Drug Metab Dispos; 2009 May; 37(5):1138-45. PubMed ID: 19237511
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices.
    Jetten MJ; Claessen SM; Dejong CH; Lahoz A; Castell JV; van Delft JH; Kleinjans JC
    Toxicology; 2014 Sep; 323():61-9. PubMed ID: 24949552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
    van Midwoud PM; Merema MT; Verpoorte E; Groothuis GM
    Lab Chip; 2010 Oct; 10(20):2778-86. PubMed ID: 20835427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel extrahepatic cytochrome P450s.
    Karlgren M; Miura S; Ingelman-Sundberg M
    Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):57-61. PubMed ID: 15987645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment of rat precision-cut fibrotic liver slice technique and its application in verapamil metabolism.
    Guo Y; Wang H; Zhang C
    Clin Exp Pharmacol Physiol; 2007; 34(5-6):406-13. PubMed ID: 17439408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of precision-cut rat liver slices for studies of xenobiotic metabolism and toxicity: comparison of the Krumdieck and Brendel tissue slicers.
    Price RJ; Ball SE; Renwick AB; Barton PT; Beamand JA; Lake BG
    Xenobiotica; 1998 Apr; 28(4):361-71. PubMed ID: 9604300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations.
    Hewitt NJ; Lecluyse EL; Ferguson SS
    Xenobiotica; 2007; 37(10-11):1196-224. PubMed ID: 17968743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.