248 related articles for article (PubMed ID: 23134353)
1. L539 fs/47, a truncated mutation of human ether-a-go-go-related gene (hERG), decreases hERG ion channel currents in HEK 293 cells.
Zhang A; Sun C; Zhang L; Lv Y; Xue X; Li G; Cui C; Yan GX
Clin Exp Pharmacol Physiol; 2013 Jan; 40(1):28-36. PubMed ID: 23134353
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological corrections of the mutant hERG channels by posaconazole.
Luo C; Zheng X; Li J; Zhang Y; Shi T; Yan Y; Han D
Clin Exp Pharmacol Physiol; 2021 Jun; 48(6):855-868. PubMed ID: 33631842
[TBL] [Abstract][Full Text] [Related]
3. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels.
Gianulis EC; Trudeau MC
J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
[TBL] [Abstract][Full Text] [Related]
4. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
5. C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
Choe CU; Schulze-Bahr E; Neu A; Xu J; Zhu ZI; Sauter K; Bähring R; Priori S; Guicheney P; Mönnig G; Neapolitano C; Heidemann J; Clancy CE; Pongs O; Isbrandt D
Hum Mol Genet; 2006 Oct; 15(19):2888-902. PubMed ID: 16923798
[TBL] [Abstract][Full Text] [Related]
6. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
7. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
[TBL] [Abstract][Full Text] [Related]
8. A novel missense mutation causing a G487R substitution in the S2-S3 loop of human ether-à-go-go-related gene channel.
Kinoshita K; Yamaguchi Y; Nishide K; Kimoto K; Nonobe Y; Fujita A; Asano K; Tabata T; Mori H; Inoue H; Hata Y; Fukurotani K; Nishida N
J Cardiovasc Electrophysiol; 2012 Nov; 23(11):1246-53. PubMed ID: 22764740
[TBL] [Abstract][Full Text] [Related]
9. Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation.
Stump MR; Gong Q; Packer JD; Zhou Z
J Mol Cell Cardiol; 2012 Nov; 53(5):725-33. PubMed ID: 22964610
[TBL] [Abstract][Full Text] [Related]
10. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
11. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
[TBL] [Abstract][Full Text] [Related]
12. LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2013 Nov; 305(9):H1397-404. PubMed ID: 23997099
[TBL] [Abstract][Full Text] [Related]
13. Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels.
Massaeli H; Guo J; Xu J; Zhang S
Circ Res; 2010 Apr; 106(6):1072-82. PubMed ID: 20133899
[TBL] [Abstract][Full Text] [Related]
14. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs.
Bai YL; Liu HB; Sun B; Zhang Y; Li Q; Hu CW; Zhu JX; Gong DM; Teng X; Zhang Q; Yang BF; Dong DL
J Mol Cell Cardiol; 2011 Nov; 51(5):876-80. PubMed ID: 21820442
[TBL] [Abstract][Full Text] [Related]
15. Electrophysiological study of V535M hERG mutation of LQT2.
Shao C; Lu Y; Liu M; Chen Q; Lan Y; Liu Y; Lin M; Li Y
J Huazhong Univ Sci Technolog Med Sci; 2011 Dec; 31(6):741-748. PubMed ID: 22173492
[TBL] [Abstract][Full Text] [Related]
16. Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C; Li P; Kurata Y; Hoshikawa Y; Morikawa K; Maharani N; Higaki K; Sasano T; Notsu T; Ishido Y; Miake J; Yamamoto Y; Shirayoshi Y; Ninomiya H; Nakai A; Murata S; Yoshida A; Yamamoto K; Hiraoka M; Hisatome I
Cardiovasc Res; 2013 Dec; 100(3):520-8. PubMed ID: 23963841
[TBL] [Abstract][Full Text] [Related]
17. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
[TBL] [Abstract][Full Text] [Related]
18. [Construction of eukaryotic expression vector of congenital long QT syndrome related HERG gene A561V mutation and its expression in HEK293 cells].
Li Y; Cui CC; Huang C; Lian JF; Zhao YH; Xue XL; Zhao XG
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2006 Dec; 23(6):627-30. PubMed ID: 17160940
[TBL] [Abstract][Full Text] [Related]
19. Multiple splicing defects caused by hERG splice site mutation 2592+1G>A associated with long QT syndrome.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2011 Jan; 300(1):H312-8. PubMed ID: 21057041
[TBL] [Abstract][Full Text] [Related]
20. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Kang Y; Guo J; Yang T; Li W; Zhang S
Biochem J; 2015 Nov; 472(1):71-82. PubMed ID: 26363003
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
