198 related articles for article (PubMed ID: 23139379)
1. Species differences in biliary clearance and possible relevance of hepatic uptake and efflux transporters involvement.
Grime K; Paine SW
Drug Metab Dispos; 2013 Feb; 41(2):372-8. PubMed ID: 23139379
[TBL] [Abstract][Full Text] [Related]
2. Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human.
Kalgutkar AS; Feng B; Nguyen HT; Frederick KS; Campbell SD; Hatch HL; Bi YA; Kazolias DC; Davidson RE; Mireles RJ; Duignan DB; Choo EF; Zhao SX
Drug Metab Dispos; 2007 Nov; 35(11):2111-8. PubMed ID: 17686907
[TBL] [Abstract][Full Text] [Related]
3. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
[TBL] [Abstract][Full Text] [Related]
4. Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.
Matsushima S; Maeda K; Kondo C; Hirano M; Sasaki M; Suzuki H; Sugiyama Y
J Pharmacol Exp Ther; 2005 Sep; 314(3):1059-67. PubMed ID: 15901800
[TBL] [Abstract][Full Text] [Related]
5. [Role of transporters in hepatic drug disposition].
Gao CY; Chen XY; Zhong DF
Yao Xue Xue Bao; 2012 May; 47(5):565-72. PubMed ID: 22811997
[TBL] [Abstract][Full Text] [Related]
6. Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites.
Patel M; Taskar KS; Zamek-Gliszczynski MJ
J Clin Pharmacol; 2016 Jul; 56 Suppl 7():S23-39. PubMed ID: 27385177
[TBL] [Abstract][Full Text] [Related]
7. Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.
Yamashiro W; Maeda K; Hirouchi M; Adachi Y; Hu Z; Sugiyama Y
Drug Metab Dispos; 2006 Jul; 34(7):1247-54. PubMed ID: 16624871
[TBL] [Abstract][Full Text] [Related]
8. Regulation of hepatic drug transporter activity and expression by organochlorine pesticides.
Bucher S; Le Vee M; Jouan E; Fardel O
J Biochem Mol Toxicol; 2014 Mar; 28(3):119-28. PubMed ID: 24464585
[TBL] [Abstract][Full Text] [Related]
9. Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.
Matsushima S; Maeda K; Hayashi H; Debori Y; Schinkel AH; Schuetz JD; Kusuhara H; Sugiyama Y
Mol Pharmacol; 2008 May; 73(5):1474-83. PubMed ID: 18245269
[TBL] [Abstract][Full Text] [Related]
10. Role of hepatic transporters in the disposition and hepatotoxicity of a HER2 tyrosine kinase inhibitor CP-724,714.
Feng B; Xu JJ; Bi YA; Mireles R; Davidson R; Duignan DB; Campbell S; Kostrubsky VE; Dunn MC; Smith AR; Wang HF
Toxicol Sci; 2009 Apr; 108(2):492-500. PubMed ID: 19223659
[TBL] [Abstract][Full Text] [Related]
11. Lack of Contribution of Multidrug Resistance-associated Protein and Organic Anion-transporting Polypeptide to Pharmacokinetics of Regorafenib, a Novel Multi-Kinase Inhibitor, in Rats.
Hotta K; Ueyama J; Tatsumi Y; Tsukiyama I; Sugiura Y; Saito H; Matsuura K; Hasegawa T
Anticancer Res; 2015 Sep; 35(9):4681-9. PubMed ID: 26254357
[TBL] [Abstract][Full Text] [Related]
12. Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.
Tian X; Li J; Zamek-Gliszczynski MJ; Bridges AS; Zhang P; Patel NJ; Raub TJ; Pollack GM; Brouwer KL
Antimicrob Agents Chemother; 2007 Sep; 51(9):3230-4. PubMed ID: 17576841
[TBL] [Abstract][Full Text] [Related]
13. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
Reese MJ; Savina PM; Generaux GT; Tracey H; Humphreys JE; Kanaoka E; Webster LO; Harmon KA; Clarke JD; Polli JW
Drug Metab Dispos; 2013 Feb; 41(2):353-61. PubMed ID: 23132334
[TBL] [Abstract][Full Text] [Related]
14. Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model.
Lundquist P; Lööf J; Fagerholm U; Sjögren I; Johansson J; Briem S; Hoogstraate J; Afzelius L; Andersson TB
Drug Metab Dispos; 2014 Mar; 42(3):459-68. PubMed ID: 24396143
[TBL] [Abstract][Full Text] [Related]
15. [A review on regulation of drug transporters during inflammation].
Zeng H; Bi HC; Huang M
Yao Xue Xue Bao; 2011 Jul; 46(7):773-9. PubMed ID: 22010345
[TBL] [Abstract][Full Text] [Related]
16. Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.
Fallon JK; Smith PC; Xia CQ; Kim MS
Pharm Res; 2016 Sep; 33(9):2280-8. PubMed ID: 27356525
[TBL] [Abstract][Full Text] [Related]
17. The hepatobiliary disposition of timosaponin b2 is highly dependent on influx/efflux transporters but not metabolism.
Sheng J; Tian X; Xu G; Wu Z; Chen C; Wang L; Pan L; Huang C; Pan G
Drug Metab Dispos; 2015 Jan; 43(1):63-72. PubMed ID: 25336752
[TBL] [Abstract][Full Text] [Related]
18. Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1.
Zamek-Gliszczynski MJ; Hoffmaster KA; Tian X; Zhao R; Polli JW; Humphreys JE; Webster LO; Bridges AS; Kalvass JC; Brouwer KL
Drug Metab Dispos; 2005 Aug; 33(8):1158-65. PubMed ID: 15860656
[TBL] [Abstract][Full Text] [Related]
19. Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin.
Hirano M; Maeda K; Matsushima S; Nozaki Y; Kusuhara H; Sugiyama Y
Mol Pharmacol; 2005 Sep; 68(3):800-7. PubMed ID: 15955871
[TBL] [Abstract][Full Text] [Related]
20. The interactions of lenalidomide with human uptake and efflux transporters and UDP-glucuronosyltransferase 1A1: lack of potential for drug-drug interactions.
Tong Z; Yerramilli U; Surapaneni S; Kumar G
Cancer Chemother Pharmacol; 2014 Apr; 73(4):869-74. PubMed ID: 24627218
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]