BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 23139789)

  • 1. A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.
    Bruns AF; Yuldasheva N; Latham AM; Bao L; Pellet-Many C; Frankel P; Stephen SL; Howell GJ; Wheatcroft SB; Kearney MT; Zachary IC; Ponnambalam S
    PLoS One; 2012; 7(11):e48539. PubMed ID: 23139789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation.
    Dietrich M; Malik MS; Nikolaysen F; Skeie M; Stang E
    Exp Cell Res; 2018 Oct; 371(1):139-150. PubMed ID: 30098331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.
    Bruns AF; Herbert SP; Odell AF; Jopling HM; Hooper NM; Zachary IC; Walker JH; Ponnambalam S
    Traffic; 2010 Jan; 11(1):161-74. PubMed ID: 19883397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.
    Le Boeuf F; Houle F; Huot J
    J Biol Chem; 2004 Sep; 279(37):39175-85. PubMed ID: 15247219
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
    Lang SA; Klein D; Moser C; Gaumann A; Glockzin G; Dahlke MH; Dietmaier W; Bolder U; Schlitt HJ; Geissler EK; Stoeltzing O
    Mol Cancer Ther; 2007 Mar; 6(3):1123-32. PubMed ID: 17363505
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor Suppression Efficacy of Heat Shock Protein 90 Inhibitor 17AAG in a Liposarcoma Mouse Model.
    Nam S; Kim H; Hong D; Park JB; Kim SJ
    Anticancer Res; 2017 Nov; 37(11):6291-6302. PubMed ID: 29061812
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF.
    Masson-Gadais B; Houle F; Laferrière J; Huot J
    Cell Stress Chaperones; 2003; 8(1):37-52. PubMed ID: 12820653
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator.
    Kaur G; Belotti D; Burger AM; Fisher-Nielson K; Borsotti P; Riccardi E; Thillainathan J; Hollingshead M; Sausville EA; Giavazzi R
    Clin Cancer Res; 2004 Jul; 10(14):4813-21. PubMed ID: 15269157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Total Flavones of Abelmoschus manihot Exhibits Pro-Angiogenic Activity by Activating the VEGF-A/VEGFR2-PI3K/Akt Signaling Axis.
    Zhu GS; Tang LY; Lv DL; Jiang M
    Am J Chin Med; 2018; 46(3):567-583. PubMed ID: 29595071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase.
    Rousseau S; Houle F; Kotanides H; Witte L; Waltenberger J; Landry J; Huot J
    J Biol Chem; 2000 Apr; 275(14):10661-72. PubMed ID: 10744763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis.
    Sanderson S; Valenti M; Gowan S; Patterson L; Ahmad Z; Workman P; Eccles SA
    Mol Cancer Ther; 2006 Mar; 5(3):522-32. PubMed ID: 16546966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling.
    Farhan MA; Azad AK; Touret N; Murray AG
    Arterioscler Thromb Vasc Biol; 2017 Dec; 37(12):2301-2310. PubMed ID: 29051140
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryptotanshinone inhibits VEGF-induced angiogenesis by targeting the VEGFR2 signaling pathway.
    Xu X; Wu L; Zhou X; Zhou N; Zhuang Q; Yang J; Dai J; Wang H; Chen S; Mao W
    Microvasc Res; 2017 May; 111():25-31. PubMed ID: 28040437
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of heat shock protein 27 using OGX-427 induces endoplasmic reticulum stress and potentiates heat shock protein 90 inhibitors to delay castrate-resistant prostate cancer.
    Lamoureux F; Thomas C; Yin MJ; Fazli L; Zoubeidi A; Gleave ME
    Eur Urol; 2014 Jul; 66(1):145-55. PubMed ID: 24411988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.
    Tiwari A; Jung JJ; Inamdar SM; Nihalani D; Choudhury A
    Am J Physiol Heart Circ Physiol; 2013 Mar; 304(5):H687-96. PubMed ID: 23262137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.
    Nieminen T; Toivanen PI; Rintanen N; Heikura T; Jauhiainen S; Airenne KJ; Alitalo K; Marjomäki V; Ylä-Herttuala S
    Biochim Biophys Acta; 2014 Jan; 1840(1):454-63. PubMed ID: 24112971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deltonin inhibits angiogenesis by regulating VEGFR2 and subsequent signaling pathways in endothelial cells.
    Tong Q; Zhao Q; Qing Y; Hu X; Jiang L; Wu X
    Steroids; 2015 Apr; 96():30-6. PubMed ID: 25554580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of osteoglycin promotes angiogenesis in limb ischaemia mouse models via modulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway.
    Wu QH; Ma Y; Ruan CC; Yang Y; Liu XH; Ge Q; Kong LR; Zhang JW; Yan C; Gao PJ
    Cardiovasc Res; 2017 Jan; 113(1):70-80. PubMed ID: 28069703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling.
    Heinolainen K; Karaman S; D'Amico G; Tammela T; Sormunen R; Eklund L; Alitalo K; Zarkada G
    Circ Res; 2017 Apr; 120(9):1414-1425. PubMed ID: 28298294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8.
    Smith GA; Fearnley GW; Abdul-Zani I; Wheatcroft SB; Tomlinson DC; Harrison MA; Ponnambalam S
    Traffic; 2016 Jan; 17(1):53-65. PubMed ID: 26459808
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.