BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

408 related articles for article (PubMed ID: 23142078)

  • 41. Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes.
    Martina JA; Puertollano R
    J Cell Biol; 2013 Feb; 200(4):475-91. PubMed ID: 23401004
    [TBL] [Abstract][Full Text] [Related]  

  • 42. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.
    Smith EM; Finn SG; Tee AR; Browne GJ; Proud CG
    J Biol Chem; 2005 May; 280(19):18717-27. PubMed ID: 15772076
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids.
    Averous J; Lambert-Langlais S; Carraro V; Gourbeyre O; Parry L; B'Chir W; Muranishi Y; Jousse C; Bruhat A; Maurin AC; Proud CG; Fafournoux P
    Cell Signal; 2014 Sep; 26(9):1918-27. PubMed ID: 24793303
    [TBL] [Abstract][Full Text] [Related]  

  • 44. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
    Huang J; Manning BD
    Biochem J; 2008 Jun; 412(2):179-90. PubMed ID: 18466115
    [TBL] [Abstract][Full Text] [Related]  

  • 45. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.
    Agarwal S; Bell CM; Taylor SM; Moran RG
    Mol Cancer Res; 2016 Jan; 14(1):66-77. PubMed ID: 26385560
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.
    Kenerson HL; Subramanian S; McIntyre R; Kazami M; Yeung RS
    PLoS One; 2015; 10(2):e0117000. PubMed ID: 25646773
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Amino acid regulation of TOR complex 1.
    Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
    Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
    [TBL] [Abstract][Full Text] [Related]  

  • 48. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
    Sancak Y; Peterson TR; Shaul YD; Lindquist RA; Thoreen CC; Bar-Peled L; Sabatini DM
    Science; 2008 Jun; 320(5882):1496-501. PubMed ID: 18497260
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Rheb and Rags come together at the lysosome to activate mTORC1.
    Groenewoud MJ; Zwartkruis FJ
    Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Lysosomal recruitment of TSC2 is a universal response to cellular stress.
    Demetriades C; Plescher M; Teleman AA
    Nat Commun; 2016 Feb; 7():10662. PubMed ID: 26868506
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Regulation of TFEB and V-ATPases by mTORC1.
    Peña-Llopis S; Vega-Rubin-de-Celis S; Schwartz JC; Wolff NC; Tran TA; Zou L; Xie XJ; Corey DR; Brugarolas J
    EMBO J; 2011 Jul; 30(16):3242-58. PubMed ID: 21804531
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
    Houssaini A; Abid S; Derumeaux G; Wan F; Parpaleix A; Rideau D; Marcos E; Kebe K; Czibik G; Sawaki D; Treins C; Dubois-Randé JL; Li Z; Amsellem V; Lipskaia L; Pende M; Adnot S
    Am J Respir Cell Mol Biol; 2016 Sep; 55(3):352-67. PubMed ID: 26991739
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Loss of TSC2 confers resistance to ceramide and nutrient deprivation.
    Guenther GG; Liu G; Ramirez MU; McMonigle RJ; Kim SM; McCracken AN; Joo Y; Ushach I; Nguyen NL; Edinger AL
    Oncogene; 2014 Apr; 33(14):1776-87. PubMed ID: 23604129
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
    Kang YJ; Lu MK; Guan KL
    Cell Death Differ; 2011 Jan; 18(1):133-44. PubMed ID: 20616807
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress.
    Lin A; Yao J; Zhuang L; Wang D; Han J; Lam EW; Gan B
    Oncogene; 2014 Jun; 33(24):3183-94. PubMed ID: 23851496
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 57. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.
    Rebsamen M; Pochini L; Stasyk T; de Araújo ME; Galluccio M; Kandasamy RK; Snijder B; Fauster A; Rudashevskaya EL; Bruckner M; Scorzoni S; Filipek PA; Huber KV; Bigenzahn JW; Heinz LX; Kraft C; Bennett KL; Indiveri C; Huber LA; Superti-Furga G
    Nature; 2015 Mar; 519(7544):477-81. PubMed ID: 25561175
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
    Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
    Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Deficiency in pulmonary surfactant proteins in mice with fatty acid binding protein 4-Cre-mediated knockout of the tuberous sclerosis complex 1 gene.
    Xiang X; Yuan F; Zhao J; Li Z; Wang X; Guan Y; Tang C; Sun G; Li Y; Zhang W
    Exp Physiol; 2013 Mar; 98(3):830-41. PubMed ID: 23143994
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
    Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
    Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.