These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 23142656)

  • 21. The role of CYP17A1 in prostate cancer development: structure, function, mechanism of action, genetic variations and its inhibition.
    Kmeťová Sivoňová M; Jurečeková J; Tatarková Z; Kaplán P; Lichardusová L; Hatok J
    Gen Physiol Biophys; 2017 Dec; 36(5):487-499. PubMed ID: 29372682
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-Hydroxylase/17,20-Lyase (P45017alpha).
    Shahid I; Patel CH; Dhanani S; Owen CP; Ahmed S
    J Steroid Biochem Mol Biol; 2008 May; 110(1-2):18-29. PubMed ID: 18407491
    [TBL] [Abstract][Full Text] [Related]  

  • 23. CYP17 inhibitors for prostate cancer treatment--an update.
    Moreira VM; Salvador JA; Vasaitis TS; Njar VC
    Curr Med Chem; 2008; 15(9):868-99. PubMed ID: 18473796
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on human and rat 17α-hydroxylase/17,20-lyase activity.
    Ye L; Chen X; Li X; Zhu Q; Yu L; Guo J; Chen B; Akingbemi BT; Ge RS; Li H
    Toxicol Lett; 2014 Mar; 225(3):407-12. PubMed ID: 24451217
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes.
    Owen CP; Shahid I; Lee WY; Ahmed S
    Bioorg Med Chem Lett; 2010 Sep; 20(17):5345-8. PubMed ID: 20675132
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
    Owen CP; Dhanani S; Patel CH; Shahid I; Ahmed S
    Bioorg Med Chem Lett; 2006 Aug; 16(15):4011-5. PubMed ID: 16750362
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 4,5-Dihydro-3-(2-pyrazinyl)naphtho[1,2-c]pyrazole: a potent and selective inhibitor of steroid-17 alpha-hydroxylase-C17,20-lyase (P450 17).
    Hartmann RW; Wächter GA; Sergejew T; Würtz R; Düerkop J
    Arch Pharm (Weinheim); 1995; 328(7-8):573-5. PubMed ID: 7492261
    [No Abstract]   [Full Text] [Related]  

  • 28. Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents.
    Wróbel TM; Rogova O; Andersen KL; Yadav R; Brixius-Anderko S; Scott EE; Olsen L; Jørgensen FS; Björkling F
    Int J Mol Sci; 2020 Jul; 21(14):. PubMed ID: 32660148
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Effects of new 17alpha-hydroxylase/C(17,20)-lyase inhibitors on LNCaP prostate cancer cell growth in vitro and in vivo.
    Grigoryev DN; Long BJ; Nnane IP; Njar VC; Liu Y; Brodie AM
    Br J Cancer; 1999 Oct; 81(4):622-30. PubMed ID: 10574247
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Partial deficiency of 17α-hydroxylase/17,20-lyase caused by a novel missense mutation in the canonical cytochrome heme-interacting motif.
    Rubtsov P; Nizhnik A; Dedov I; Kalinchenko N; Petrov V; Orekhova A; Spirin P; Prassolov V; Tiulpakov A
    Eur J Endocrinol; 2015 May; 172(5):K19-25. PubMed ID: 25650406
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Modeling study of some inhibitors of 17,20-lyase, a component of the enzyme 17 alpha-hydroxylase/17,20-lyase: a novel approach.
    Ahmed S; Keane J
    Biochem Biophys Res Commun; 1998 Dec; 253(2):273-6. PubMed ID: 9878527
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of 17alpha-hydroxylase/C17,20-lyase (CYP17) from rat testis by green tea catechins and black tea theaflavins.
    Kimura K; Itakura Y; Goto R; Tojima M; Egawa N; Yoshihama M
    Biosci Biotechnol Biochem; 2007 Sep; 71(9):2325-8. PubMed ID: 17827674
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats.
    Hara T; Kouno J; Kaku T; Takeuchi T; Kusaka M; Tasaka A; Yamaoka M
    J Steroid Biochem Mol Biol; 2013 Mar; 134():80-91. PubMed ID: 23146910
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone.
    Garrido M; Peng HM; Yoshimoto FK; Upadhyay SK; Bratoeff E; Auchus RJ
    J Steroid Biochem Mol Biol; 2014 Sep; 143():1-10. PubMed ID: 24508512
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Determination of 17α-hydroxylase-C17,20-lyase (P45017α) enzyme activities and their inhibition by selected steroidal picolyl and picolinylidene compounds.
    Szabó N; Ajduković JJ; Djurendić EA; Sakač MN; Ignáth I; Gardi J; Mahmoud G; Klisurić OR; Jovanović-Šanta S; Penov Gaši KM; Szécsi M
    Acta Biol Hung; 2015 Mar; 66(1):41-51. PubMed ID: 25740437
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Novel steroidal pyrimidyl inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase).
    Haidar S; Ehmer PB; Hartmann RW
    Arch Pharm (Weinheim); 2001 Dec; 334(12):373-4. PubMed ID: 11852531
    [No Abstract]   [Full Text] [Related]  

  • 37. Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis.
    Klus GT; Nakamura J; Li JS; Ling YZ; Son C; Kemppainen JA; Wilson EM; Brodie AM
    Cancer Res; 1996 Nov; 56(21):4956-64. PubMed ID: 8895750
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 17,20-Lyase inhibitors. Part 3: Design, synthesis, and structure-activity relationships of biphenylylmethylimidazole derivatives as novel 17,20-lyase inhibitors.
    Kaku T; Tsujimoto S; Matsunaga N; Tanaka T; Hara T; Yamaoka M; Kusaka M; Tasaka A
    Bioorg Med Chem; 2011 Apr; 19(7):2428-42. PubMed ID: 21429754
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibitors of 17alpha-hydroxylase/17,20-lyase (CYP17): potential agents for the treatment of prostate cancer.
    Njar VC; Brodie AM
    Curr Pharm Des; 1999 Mar; 5(3):163-80. PubMed ID: 10066888
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Novel oxazolinyl derivatives of pregna-5,17(20)-diene as 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitors.
    Kuzikov AV; Dugin NO; Stulov SV; Shcherbinin DS; Zharkova MS; Tkachev YV; Timofeev VP; Veselovsky AV; Shumyantseva VV; Misharin AY
    Steroids; 2014 Oct; 88():66-71. PubMed ID: 24971814
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.