BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 23144635)

  • 1. A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation.
    Yamtich J; Nemec AA; Keh A; Sweasy JB
    PLoS Genet; 2012; 8(11):e1003052. PubMed ID: 23144635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.
    Nemec AA; Donigan KA; Murphy DL; Jaeger J; Sweasy JB
    J Biol Chem; 2012 Jul; 287(28):23840-9. PubMed ID: 22573322
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.
    Nemec AA; Murphy DL; Donigan KA; Sweasy JB
    J Biol Chem; 2014 May; 289(20):13708-16. PubMed ID: 24668809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.
    Nemec AA; Abriola L; Merkel JS; de Stanchina E; DeVeaux M; Zelterman D; Glazer PM; Sweasy JB
    Mol Cancer Res; 2017 Mar; 15(3):269-280. PubMed ID: 28074003
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genome instability caused by a germline mutation in the human DNA repair gene POLB.
    Sobol RW
    PLoS Genet; 2012; 8(11):e1003086. PubMed ID: 23144636
    [No Abstract]   [Full Text] [Related]  

  • 6. Cellular roles of DNA polymerase beta.
    Ray S; Menezes MR; Senejani A; Sweasy JB
    Yale J Biol Med; 2013 Dec; 86(4):463-9. PubMed ID: 24348210
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-Associated R438W DNA Polymerase Lambda Protein.
    Nemec AA; Bush KB; Towle-Weicksel JB; Taylor BF; Schulz V; Weidhaas JB; Tuck DP; Sweasy JB
    Mol Cancer Res; 2016 Nov; 14(11):1068-1077. PubMed ID: 27621267
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation.
    Sjolund A; Nemec AA; Paquet N; Prakash A; Sung P; Doublié S; Sweasy JB
    PLoS Genet; 2014 Nov; 10(11):e1004753. PubMed ID: 25375110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo.
    Cabelof DC; Raffoul JJ; Yanamadala S; Guo Z; Heydari AR
    Carcinogenesis; 2002 Sep; 23(9):1419-25. PubMed ID: 12189182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.
    Senejani AG; Dalal S; Liu Y; Nottoli TP; McGrath JM; Clairmont CS; Sweasy JB
    Proc Natl Acad Sci U S A; 2012 Apr; 109(17):6632-7. PubMed ID: 22493258
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
    Çağlayan M; Horton JK; Dai DP; Stefanick DF; Wilson SH
    Nat Commun; 2017 Jan; 8():14045. PubMed ID: 28067232
    [TBL] [Abstract][Full Text] [Related]  

  • 12. R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation.
    Zhou T; Pan F; Cao Y; Han Y; Zhao J; Sun H; Zhou X; Wu X; He L; Hu Z; Chen H; Shen B; Guo Z
    Oncotarget; 2016 Feb; 7(6):6902-15. PubMed ID: 26760506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA polymerase β variant Ile260Met generates global gene expression changes related to cellular transformation.
    Donigan KA; Tuck D; Schulz V; Sweasy JB
    Mutagenesis; 2012 Nov; 27(6):683-91. PubMed ID: 22914675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks.
    Rozacky J; Nemec AA; Sweasy JB; Kidane D
    Oncotarget; 2015 Sep; 6(27):24474-87. PubMed ID: 26090616
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of DNA polymerase beta in repairing oxidative damages induced by antitumor drug adriamycin.
    Liu S; Wu M; Zhang Z
    Toxicol Appl Pharmacol; 2010 Aug; 246(3):163-70. PubMed ID: 20510258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.
    Jiang Z; Xu M; Lai Y; Laverde EE; Terzidis MA; Masi A; Chatgilialoglu C; Liu Y
    DNA Repair (Amst); 2015 Sep; 33():24-34. PubMed ID: 26123757
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair.
    Çağlayan M; Wilson SH
    DNA Repair (Amst); 2015 Nov; 35():85-9. PubMed ID: 26466358
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ.
    Terrados G; Capp JP; Canitrot Y; García-Díaz M; Bebenek K; Kirchhoff T; Villanueva A; Boudsocq F; Bergoglio V; Cazaux C; Kunkel TA; Hoffmann JS; Blanco L
    PLoS One; 2009 Oct; 4(10):e7290. PubMed ID: 19806195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The R280H X-ray cross-complementing 1 germline variant induces genomic instability and cellular transformation.
    Sizova DV; Keh A; Taylor BF; Sweasy JB
    DNA Repair (Amst); 2015 Jul; 31():73-9. PubMed ID: 26011397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase beta in long patch base excision repair.
    Sukhanova M; Khodyreva S; Lavrik O
    Mutat Res; 2010 Mar; 685(1-2):80-9. PubMed ID: 19703477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.