These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 23144714)

  • 1. UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.
    Mann MJ; Pereira ER; Liao N; Hendershot LM
    PLoS One; 2012; 7(10):e47931. PubMed ID: 23144714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response.
    Ma Y; Shimizu Y; Mann MJ; Jin Y; Hendershot LM
    Cell Stress Chaperones; 2010 May; 15(3):281-93. PubMed ID: 19898960
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response.
    Gupta A; Hossain MM; Read DE; Hetz C; Samali A; Gupta S
    Sci Rep; 2015 Dec; 5():18304. PubMed ID: 26674075
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
    Gjymishka A; Su N; Kilberg MS
    Biochem J; 2009 Feb; 417(3):695-703. PubMed ID: 18840095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
    Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH
    Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis.
    Deldicque L; Cani PD; Philp A; Raymackers JM; Meakin PJ; Ashford ML; Delzenne NM; Francaux M; Baar K
    Am J Physiol Endocrinol Metab; 2010 Nov; 299(5):E695-705. PubMed ID: 20501874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
    Muñoz JP; Ivanova S; Sánchez-Wandelmer J; Martínez-Cristóbal P; Noguera E; Sancho A; Díaz-Ramos A; Hernández-Alvarez MI; Sebastián D; Mauvezin C; Palacín M; Zorzano A
    EMBO J; 2013 Aug; 32(17):2348-61. PubMed ID: 23921556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.
    Shi K; Wang D; Cao X; Ge Y
    PLoS One; 2013; 8(3):e59330. PubMed ID: 23533616
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ectopic expression of human topoisomerase IIalpha fragments and etoposide resistance in mammalian cells.
    Ernst AI; Soltermann A; Sigrist JA; Widmer L; Gasser SM; Stahel RA
    Int J Cancer; 2000 Oct; 88(1):99-107. PubMed ID: 10962446
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress.
    Luhr M; Torgersen ML; Szalai P; Hashim A; Brech A; Staerk J; Engedal N
    J Biol Chem; 2019 May; 294(20):8197-8217. PubMed ID: 30926605
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PI 3-kinase regulatory subunits as regulators of the unfolded protein response.
    Winnay JN; Kahn CR
    Methods Enzymol; 2011; 490():147-58. PubMed ID: 21266249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors.
    Oloumi A; MacPhail SH; Johnston PJ; Banáth JP; Olive PL
    Cancer Res; 2000 Oct; 60(20):5747-53. PubMed ID: 11059769
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding.
    Manga P; Bis S; Knoll K; Perez B; Orlow SJ
    Pigment Cell Melanoma Res; 2010 Oct; 23(5):627-34. PubMed ID: 20444203
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.
    Ogborn DI; McKay BR; Crane JD; Parise G; Tarnopolsky MA
    Am J Physiol Regul Integr Comp Physiol; 2014 Sep; 307(6):R664-9. PubMed ID: 25009220
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress.
    Takayanagi S; Fukuda R; Takeuchi Y; Tsukada S; Yoshida K
    Cell Stress Chaperones; 2013 Jan; 18(1):11-23. PubMed ID: 22802018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting UPR branches, a potential strategy for enhancing efficacy of cancer chemotherapy.
    Yu M; Lun J; Zhang H; Wang L; Zhang G; Zhang H; Fang J
    Acta Biochim Biophys Sin (Shanghai); 2021 Nov; 53(11):1417-1427. PubMed ID: 34664059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of the unfolded protein response is necessary and sufficient for reducing topoisomerase IIalpha protein levels and decreasing sensitivity to topoisomerase-targeted drugs.
    Gray MD; Mann M; Nitiss JL; Hendershot LM
    Mol Pharmacol; 2005 Dec; 68(6):1699-707. PubMed ID: 16141312
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status.
    Moore K; Hollien J
    Mol Biol Cell; 2015 Aug; 26(16):2873-84. PubMed ID: 26108623
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.
    Tay KH; Luan Q; Croft A; Jiang CC; Jin L; Zhang XD; Tseng HY
    Cell Signal; 2014 Feb; 26(2):287-94. PubMed ID: 24240056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of topoisomerase IIalpha expression by a DNA sequence-specific polyamide.
    Hochhauser D; Kotecha M; O'hare C; Morris PJ; Hartley JM; Taherbhai Z; Harris D; Forni C; Mantovani R; Lee M; Hartley JA
    Mol Cancer Ther; 2007 Jan; 6(1):346-54. PubMed ID: 17237293
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.