599 related articles for article (PubMed ID: 23145493)
1. The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613.
Hourihan JM; Kenna JG; Hayes JD
Antioxid Redox Signal; 2013 Aug; 19(5):465-81. PubMed ID: 23145493
[TBL] [Abstract][Full Text] [Related]
2. Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2.
Yang G; Zhao K; Ju Y; Mani S; Cao Q; Puukila S; Khaper N; Wu L; Wang R
Antioxid Redox Signal; 2013 May; 18(15):1906-19. PubMed ID: 23176571
[TBL] [Abstract][Full Text] [Related]
3. S-1-propenylmercaptocysteine protects murine hepatocytes against oxidative stress via persulfidation of Keap1 and activation of Nrf2.
Tocmo R; Parkin K
Free Radic Biol Med; 2019 Nov; 143():164-175. PubMed ID: 31349040
[TBL] [Abstract][Full Text] [Related]
4. Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation.
Meng W; Pei Z; Feng Y; Zhao J; Chen Y; Shi W; Xu Q; Lin F; Sun M; Xiao K
Sci Rep; 2017 Aug; 7(1):9433. PubMed ID: 28842592
[TBL] [Abstract][Full Text] [Related]
5. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
Sun Z; Zhang S; Chan JY; Zhang DD
Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
[TBL] [Abstract][Full Text] [Related]
6. The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2.
Yang H; Mao Y; Tan B; Luo S; Zhu Y
Eur J Pharmacol; 2015 Aug; 761():135-43. PubMed ID: 25979858
[TBL] [Abstract][Full Text] [Related]
7. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
Rojo AI; Medina-Campos ON; Rada P; Zúñiga-Toalá A; López-Gazcón A; Espada S; Pedraza-Chaverri J; Cuadrado A
Free Radic Biol Med; 2012 Jan; 52(2):473-87. PubMed ID: 22142471
[TBL] [Abstract][Full Text] [Related]
8. Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway.
Guo C; Liang F; Shah Masood W; Yan X
Eur J Pharmacol; 2014 Feb; 725():70-8. PubMed ID: 24444438
[TBL] [Abstract][Full Text] [Related]
9. Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
McMahon M; Swift SR; Hayes JD
Toxicol Appl Pharmacol; 2018 Dec; 360():45-57. PubMed ID: 30261176
[TBL] [Abstract][Full Text] [Related]
10. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
Lo SC; Hannink M
Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
[TBL] [Abstract][Full Text] [Related]
11. Activation of NRF2 by nitrosative agents and H2O2 involves KEAP1 disulfide formation.
Fourquet S; Guerois R; Biard D; Toledano MB
J Biol Chem; 2010 Mar; 285(11):8463-71. PubMed ID: 20061377
[TBL] [Abstract][Full Text] [Related]
12. Hydrogen sulfide protects retinal pigment epithelium cells against ferroptosis through the AMPK- and p62-dependent non-canonical NRF2-KEAP1 pathway.
Yu M; Wang W; Dang J; Liu B; Xu J; Li J; Liu Y; He L; Ying Y; Cai J; Cheng G; Liu K
Exp Cell Res; 2023 Jan; 422(1):113436. PubMed ID: 36435220
[TBL] [Abstract][Full Text] [Related]
13. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.
Yang SP; Yang XZ; Cao GP
Mol Med Rep; 2015 Jul; 12(1):1145-50. PubMed ID: 25776802
[TBL] [Abstract][Full Text] [Related]
14. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
15. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
Hayes JD; McMahon M; Chowdhry S; Dinkova-Kostova AT
Antioxid Redox Signal; 2010 Dec; 13(11):1713-48. PubMed ID: 20446772
[TBL] [Abstract][Full Text] [Related]
16. Hydrogen sulfide (H2S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways.
Zheng J; Zhao T; Yuan Y; Hu N; Tang X
Chem Biol Interact; 2015 Dec; 242():353-62. PubMed ID: 26523793
[TBL] [Abstract][Full Text] [Related]
17. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
Ohnuma T; Nakayama S; Anan E; Nishiyama T; Ogura K; Hiratsuka A
Toxicol Appl Pharmacol; 2010 Apr; 244(1):27-36. PubMed ID: 20026152
[TBL] [Abstract][Full Text] [Related]
18. Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the SLC7A11/GSH/GPx4 pathway by Keap1 S-sulfhydration and Nrf2 activation.
Zhang H; Pan J; Huang S; Chen X; Chang ACY; Wang C; Zhang J; Zhang H
Redox Biol; 2024 Apr; 70():103066. PubMed ID: 38359744
[TBL] [Abstract][Full Text] [Related]
19. Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Lo SC; Li X; Henzl MT; Beamer LJ; Hannink M
EMBO J; 2006 Aug; 25(15):3605-17. PubMed ID: 16888629
[TBL] [Abstract][Full Text] [Related]
20. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease.
Tebay LE; Robertson H; Durant ST; Vitale SR; Penning TM; Dinkova-Kostova AT; Hayes JD
Free Radic Biol Med; 2015 Nov; 88(Pt B):108-146. PubMed ID: 26122708
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
