BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 23146662)

  • 1. Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action.
    Kedei N; Telek A; Michalowski AM; Kraft MB; Li W; Poudel YB; Rudra A; Petersen ME; Keck GE; Blumberg PM
    Biochem Pharmacol; 2013 Feb; 85(3):313-24. PubMed ID: 23146662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line.
    Kedei N; Telek A; Czap A; Lubart ES; Czifra G; Yang D; Chen J; Morrison T; Goldsmith PK; Lim L; Mannan P; Garfield SH; Kraft MB; Li W; Keck GE; Blumberg PM
    Biochem Pharmacol; 2011 Jun; 81(11):1296-308. PubMed ID: 21458422
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Some phorbol esters might partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cells.
    Kedei N; Lubart E; Lewin NE; Telek A; Lim L; Mannan P; Garfield SH; Kraft MB; Keck GE; Kolusheva S; Jelinek R; Blumberg PM
    Chembiochem; 2011 May; 12(8):1242-51. PubMed ID: 21542090
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological activity of the bryostatin analog Merle 23 on mouse epidermal cells and mouse skin.
    Kelsey JS; Cataisson C; Chen J; Herrmann MA; Petersen ME; Baumann DO; McGowan KM; Yuspa SH; Keck GE; Blumberg PM
    Mol Carcinog; 2016 Dec; 55(12):2183-2195. PubMed ID: 26859836
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neristatin 1 provides critical insight into bryostatin 1 structure-function relationships.
    Kedei N; Kraft MB; Keck GE; Herald CL; Melody N; Pettit GR; Blumberg PM
    J Nat Prod; 2015 Apr; 78(4):896-900. PubMed ID: 25808573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bryostatin 1 inhibits phorbol ester-induced apoptosis in prostate cancer cells by differentially modulating protein kinase C (PKC) delta translocation and preventing PKCdelta-mediated release of tumor necrosis factor-alpha.
    von Burstin VA; Xiao L; Kazanietz MG
    Mol Pharmacol; 2010 Sep; 78(3):325-32. PubMed ID: 20516369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contrasting duration of inhibition of cell-cell communication in primary mouse epidermal cells by phorbol 12,13-dibutyrate and by bryostatin 1.
    Pasti G; Rivedal E; Yuspa SH; Herald CL; Pettit GR; Blumberg PM
    Cancer Res; 1988 Jan; 48(2):447-51. PubMed ID: 3422054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential effects of bryostatins and phorbol esters on arachidonic acid metabolite release and epidermal growth factor binding in C3H 10T1/2 cells.
    Dell'Aquila ML; Herald CL; Kamano Y; Pettit GR; Blumberg PM
    Cancer Res; 1988 Jul; 48(13):3702-8. PubMed ID: 3132318
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells.
    Dell'Aquila ML; Nguyen HT; Herald CL; Pettit GR; Blumberg PM
    Cancer Res; 1987 Nov; 47(22):6006-9. PubMed ID: 3478136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and Biological Evaluation of Fluorescent Bryostatin Analogues.
    Cummins TJ; Kedei N; Czikora A; Lewin NE; Kirk S; Petersen ME; McGowan KM; Chen JQ; Luo X; Johnson RC; Ravichandran S; Blumberg PM; Keck GE
    Chembiochem; 2018 Apr; 19(8):877-889. PubMed ID: 29424951
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.
    Keck GE; Poudel YB; Welch DS; Kraft MB; Truong AP; Stephens JC; Kedei N; Lewin NE; Blumberg PM
    Org Lett; 2009 Feb; 11(3):593-6. PubMed ID: 19113896
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insights into the interactions of phorbol ester and bryostatin complexed with protein kinase C: a comparative molecular dynamics simulation study.
    Thangsunan P; Tateing S; Hannongbua S; Suree N
    J Biomol Struct Dyn; 2016 Jul; 34(7):1561-75. PubMed ID: 26292580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells.
    Sako T; Yuspa SH; Herald CL; Pettit GR; Blumberg PM
    Cancer Res; 1987 Oct; 47(20):5445-50. PubMed ID: 2888531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of Chromane-Based Bryostatin Analogues Prepared via Hydrogen-Mediated C-C Bond Formation: Potency Does Not Confer Bryostatin-like Biology.
    Ketcham JM; Volchkov I; Chen TY; Blumberg PM; Kedei N; Lewin NE; Krische MJ
    J Am Chem Soc; 2016 Oct; 138(40):13415-13423. PubMed ID: 27676096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation.
    Mackanos EA; Pettit GR; Ramsdell JS
    J Biol Chem; 1991 Jun; 266(17):11205-12. PubMed ID: 1904062
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.
    Kraft AS; Smith JB; Berkow RL
    Proc Natl Acad Sci U S A; 1986 Mar; 83(5):1334-8. PubMed ID: 3456591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.
    Wender PA; DeBrabander J; Harran PG; Jimenez JM; Koehler MF; Lippa B; Park CM; Siedenbiedel C; Pettit GR
    Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6624-9. PubMed ID: 9618462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937).
    Vrana JA; Saunders AM; Chellappan SP; Grant S
    Differentiation; 1998 May; 63(1):33-42. PubMed ID: 9615391
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Two protein kinase C activators, bryostatin-1 and phorbol-12-myristate-13-acetate, have different effects on haemopoietic cell proliferation and differentiation.
    Ng SB; Guy GR
    Cell Signal; 1992 Jul; 4(4):405-16. PubMed ID: 1419483
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells.
    Stanwell C; Gescher A; Bradshaw TD; Pettit GR
    Int J Cancer; 1994 Feb; 56(4):585-92. PubMed ID: 8112895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.