BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

513 related articles for article (PubMed ID: 23147248)

  • 1. A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding.
    van de Meerakker JB; Christiaans I; Barnett P; Lekanne Deprez RH; Ilgun A; Mook OR; Mannens MM; Lam J; Wilde AA; Moorman AF; Postma AV
    Biochim Biophys Acta; 2013 Apr; 1833(4):833-9. PubMed ID: 23147248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. M8R tropomyosin mutation disrupts actin binding and filament regulation: The beginning affects the middle and end.
    Racca AW; Rynkiewicz MJ; LaFave N; Ghosh A; Lehman W; Moore JR
    J Biol Chem; 2020 Dec; 295(50):17128-17137. PubMed ID: 33020181
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of novel mutations including a double mutation in patients with inherited cardiomyopathy by a targeted sequencing approach using the Ion Torrent PGM system.
    Zhao Y; Cao H; Song Y; Feng Y; Ding X; Pang M; Zhang Y; Zhang H; Ding J; Xia X
    Int J Mol Med; 2016 Jun; 37(6):1511-20. PubMed ID: 27082122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cardiomyopathy-associated K15N mutation in tropomyosin alters actin filament pointed end dynamics.
    Colpan M; Ly T; Grover S; Tolkatchev D; Kostyukova AS
    Arch Biochem Biophys; 2017 Sep; 630():18-26. PubMed ID: 28732641
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Rajan S; Ahmed RP; Jagatheesan G; Petrashevskaya N; Boivin GP; Urboniene D; Arteaga GM; Wolska BM; Solaro RJ; Liggett SB; Wieczorek DF
    Circ Res; 2007 Jul; 101(2):205-14. PubMed ID: 17556658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Abnormal tropomyosin function in ATPase cycle in hypertrophic and dilated cardiomyopathies].
    Borovikov IuS; Karpicheva OE; Rysev NA; Redwood CS
    Ross Fiziol Zh Im I M Sechenova; 2013 Jan; 99(1):73-80. PubMed ID: 23659058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy.
    Olson TM; Kishimoto NY; Whitby FG; Michels VV
    J Mol Cell Cardiol; 2001 Apr; 33(4):723-32. PubMed ID: 11273725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coexistence of Digenic Mutations in Both Thin (TPM1) and Thick (MYH7) Filaments of Sarcomeric Genes Leads to Severe Hypertrophic Cardiomyopathy in a South Indian FHCM.
    Selvi Rani D; Nallari P; Dhandapany PS; Rani J; Meraj K; Ganesan M; Narasimhan C; Thangaraj K
    DNA Cell Biol; 2015 May; 34(5):350-9. PubMed ID: 25607779
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel homozygous TPM1 mutation in familial pediatric hypertrophic cardiomyopathy and in silico screening of potential targeting drugs.
    Carlus SJ; Almuzaini IS; Karthikeyan M; Loganathan L; Al-Harbi GS; Carlus FH; Al-Mazroea AH; Morsy MM; Abo-Haded HM; Abdallah AM; Al-Harbi KM
    Eur Rev Med Pharmacol Sci; 2020 Jul; 24(14):7732-7744. PubMed ID: 32744700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.
    Lakdawala NK; Dellefave L; Redwood CS; Sparks E; Cirino AL; Depalma S; Colan SD; Funke B; Zimmerman RS; Robinson P; Watkins H; Seidman CE; Seidman JG; McNally EM; Ho CY
    J Am Coll Cardiol; 2010 Jan; 55(4):320-9. PubMed ID: 20117437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Localization of the binding interface between leiomodin-2 and α-tropomyosin.
    Colpan M; Tolkatchev D; Grover S; Helms GL; Cort JR; Moroz N; Kostyukova AS
    Biochim Biophys Acta; 2016 May; 1864(5):523-30. PubMed ID: 26873245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle.
    Borovikov YS; Avrova SV; Karpicheva OE; Robinson P; Redwood CS
    Biochem Biophys Res Commun; 2011 Aug; 411(3):496-500. PubMed ID: 21741356
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alpha-tropomyosin mutations in inherited cardiomyopathies.
    Redwood C; Robinson P
    J Muscle Res Cell Motil; 2013 Aug; 34(3-4):285-94. PubMed ID: 24005378
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Variable clinical manifestation of a novel missense mutation in the alpha-tropomyosin (TPM1) gene in familial hypertrophic cardiomyopathy.
    Jongbloed RJ; Marcelis CL; Doevendans PA; Schmeitz-Mulkens JM; Van Dockum WG; Geraedts JP; Smeets HJ
    J Am Coll Cardiol; 2003 Mar; 41(6):981-6. PubMed ID: 12651045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
    Robinson P; Griffiths PJ; Watkins H; Redwood CS
    Circ Res; 2007 Dec; 101(12):1266-73. PubMed ID: 17932326
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy.
    Carballo S; Robinson P; Otway R; Fatkin D; Jongbloed JD; de Jonge N; Blair E; van Tintelen JP; Redwood C; Watkins H
    Circ Res; 2009 Aug; 105(4):375-82. PubMed ID: 19590045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca
    Robinson P; Sparrow AJ; Patel S; Malinowska M; Reilly SN; Zhang YH; Casadei B; Watkins H; Redwood C
    Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H306-H319. PubMed ID: 32618513
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.
    Lynn ML; Tal Grinspan L; Holeman TA; Jimenez J; Strom J; Tardiff JC
    J Mol Cell Cardiol; 2017 Jul; 108():127-137. PubMed ID: 28600229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a novel missense mutation in the TPM1 gene via exome sequencing in a Chinese family with dilated cardiomyopathy: A case report and literature review.
    Man Y; Yi C; Fan M; Yang T; Liu P; Liu S; Wang G
    Medicine (Baltimore); 2022 Jan; 101(2):e28551. PubMed ID: 35029218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GATA5 loss-of-function mutation in familial dilated cardiomyopathy.
    Zhang XL; Dai N; Tang K; Chen YQ; Chen W; Wang J; Zhao CM; Yuan F; Qiu XB; Qu XK; Yang YQ; Xu YW
    Int J Mol Med; 2015 Mar; 35(3):763-70. PubMed ID: 25543888
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.