246 related articles for article (PubMed ID: 23148209)
1. Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK.
Harding HP; Zyryanova AF; Ron D
J Biol Chem; 2012 Dec; 287(53):44338-44. PubMed ID: 23148209
[TBL] [Abstract][Full Text] [Related]
2. The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.
Sowers CR; Wang R; Bourne RA; McGrath BC; Hu J; Bevilacqua SC; Paton JC; Paton AW; Collardeau-Frachon S; Nicolino M; Cavener DR
J Biol Chem; 2018 Apr; 293(14):5134-5149. PubMed ID: 29444822
[TBL] [Abstract][Full Text] [Related]
3. PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.
Moore CE; Omikorede O; Gomez E; Willars GB; Herbert TP
Mol Endocrinol; 2011 Feb; 25(2):315-26. PubMed ID: 21193559
[TBL] [Abstract][Full Text] [Related]
4. Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.
Linssen MM; van Raalte DH; Toonen EJ; Alkema W; van der Zon GC; Dokter WH; Diamant M; Guigas B; Ouwens DM
Cell Signal; 2011 Nov; 23(11):1708-15. PubMed ID: 21689745
[TBL] [Abstract][Full Text] [Related]
5. Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells.
Sargsyan E; Ortsäter H; Thorn K; Bergsten P
J Endocrinol; 2008 Oct; 199(1):41-50. PubMed ID: 18644846
[TBL] [Abstract][Full Text] [Related]
6. Attenuation of PERK enhances glucose-stimulated insulin secretion in islets.
Kim MJ; Min SH; Shin SY; Kim MN; Lee H; Jang JY; Kim SW; Park KS; Jung HS
J Endocrinol; 2018 Mar; 236(3):125-136. PubMed ID: 29273589
[TBL] [Abstract][Full Text] [Related]
7. The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation.
Ozasa R; Okada T; Nadanaka S; Nagamine T; Zyryanova A; Harding H; Ron D; Mori K
Cell Struct Funct; 2013; 38(2):183-95. PubMed ID: 23812432
[TBL] [Abstract][Full Text] [Related]
8. Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.
Feng D; Wei J; Gupta S; McGrath BC; Cavener DR
BMC Cell Biol; 2009 Sep; 10():61. PubMed ID: 19732428
[TBL] [Abstract][Full Text] [Related]
9. Type I interferons mediate pancreatic toxicities of PERK inhibition.
Yu Q; Zhao B; Gui J; Katlinski KV; Brice A; Gao Y; Li C; Kushner JA; Koumenis C; Diehl JA; Fuchs SY
Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15420-5. PubMed ID: 26627716
[TBL] [Abstract][Full Text] [Related]
10. PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.
Gao Y; Sartori DJ; Li C; Yu QC; Kushner JA; Simon MC; Diehl JA
Mol Cell Biol; 2012 Dec; 32(24):5129-39. PubMed ID: 23071091
[TBL] [Abstract][Full Text] [Related]
11. PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis.
Wang YC; Li X; Shen Y; Lyu J; Sheng H; Paschen W; Yang W
Stroke; 2020 May; 51(5):1570-1577. PubMed ID: 32212900
[TBL] [Abstract][Full Text] [Related]
12. Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.
Wang R; Munoz EE; Zhu S; McGrath BC; Cavener DR
PLoS One; 2014; 9(6):e99684. PubMed ID: 24915520
[TBL] [Abstract][Full Text] [Related]
13. Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs.
Bollo M; Paredes RM; Holstein D; Zheleznova N; Camacho P; Lechleiter JD
PLoS One; 2010 Aug; 5(8):e11925. PubMed ID: 20700529
[TBL] [Abstract][Full Text] [Related]
14. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Harding HP; Zeng H; Zhang Y; Jungries R; Chung P; Plesken H; Sabatini DD; Ron D
Mol Cell; 2001 Jun; 7(6):1153-63. PubMed ID: 11430819
[TBL] [Abstract][Full Text] [Related]
15. Perk is essential for translational regulation and cell survival during the unfolded protein response.
Harding HP; Zhang Y; Bertolotti A; Zeng H; Ron D
Mol Cell; 2000 May; 5(5):897-904. PubMed ID: 10882126
[TBL] [Abstract][Full Text] [Related]
16. Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation.
Ron D; Harding HP
Cold Spring Harb Perspect Biol; 2012 Dec; 4(12):. PubMed ID: 23209157
[TBL] [Abstract][Full Text] [Related]
17. Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.
Saito A; Ochiai K; Kondo S; Tsumagari K; Murakami T; Cavener DR; Imaizumi K
J Biol Chem; 2011 Feb; 286(6):4809-18. PubMed ID: 21135100
[TBL] [Abstract][Full Text] [Related]
18. The endoplasmic reticulum stress response in the pancreatic β-cell.
Volchuk A; Ron D
Diabetes Obes Metab; 2010 Oct; 12 Suppl 2():48-57. PubMed ID: 21029300
[TBL] [Abstract][Full Text] [Related]
19. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.
Akerfeldt MC; Howes J; Chan JY; Stevens VA; Boubenna N; McGuire HM; King C; Biden TJ; Laybutt DR
Diabetes; 2008 Nov; 57(11):3034-44. PubMed ID: 18591394
[TBL] [Abstract][Full Text] [Related]
20. The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
Teske BF; Wek SA; Bunpo P; Cundiff JK; McClintick JN; Anthony TG; Wek RC
Mol Biol Cell; 2011 Nov; 22(22):4390-405. PubMed ID: 21917591
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
