These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
138 related articles for article (PubMed ID: 23149763)
1. Can cyclic HIV protease inhibitors bind in a non-preferred form? An ab initio, DFT and MM-PB(GB)SA study. Oehme DP; Brownlee RT; Wilson DJ J Mol Model; 2013 Mar; 19(3):1125-42. PubMed ID: 23149763 [TBL] [Abstract][Full Text] [Related]
2. Inhibitors of the C(2)-symmetric HIV-1 protease: nonsymmetric binding of a symmetric cyclic sulfamide with ketoxime groups in the P2/P2' side chains. Hultén J; Andersson HO; Schaal W; Danielson HU; Classon B; Kvarnström I; Karlén A; Unge T; Samuelsson B; Hallberg A J Med Chem; 1999 Oct; 42(20):4054-61. PubMed ID: 10514275 [TBL] [Abstract][Full Text] [Related]
3. Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor. Bäckbro K; Löwgren S; Osterlund K; Atepo J; Unge T; Hultén J; Bonham NM; Schaal W; Karlén A; Hallberg A J Med Chem; 1997 Mar; 40(6):898-902. PubMed ID: 9083478 [TBL] [Abstract][Full Text] [Related]
4. Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors. Lam PY; Jadhav PK; Eyermann CJ; Hodge CN; Ru Y; Bacheler LT; Meek JL; Otto MJ; Rayner MM; Wong YN Science; 1994 Jan; 263(5145):380-4. PubMed ID: 8278812 [TBL] [Abstract][Full Text] [Related]
5. Potent cyclic urea HIV protease inhibitors with 3-aminoindazole P2/P2' groups. Rodgers JD; Johnson BL; Wang H; Erickson-Viitanen S; Klabe RM; Bacheler L; Cordova BC; Chang CH Bioorg Med Chem Lett; 1998 Apr; 8(7):715-20. PubMed ID: 9871528 [TBL] [Abstract][Full Text] [Related]
6. Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies. Jadhav PK; Woerner FJ; Lam PY; Hodge CN; Eyermann CJ; Man HW; Daneker WF; Bacheler LT; Rayner MM; Meek JL; Erickson-Viitanen S; Jackson DA; Calabrese JC; Schadt M; Chang CH J Med Chem; 1998 Apr; 41(9):1446-55. PubMed ID: 9554878 [TBL] [Abstract][Full Text] [Related]
7. Interpreting trends in the binding of cyclic ureas to HIV-1 protease. Mardis KL; Luo R; Gilson MK J Mol Biol; 2001 Jun; 309(2):507-17. PubMed ID: 11371168 [TBL] [Abstract][Full Text] [Related]
8. Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors. Schaal W; Karlsson A; Ahlsén G; Lindberg J; Andersson HO; Danielson UH; Classon B; Unge T; Samuelsson B; Hultén J; Hallberg A; Karlén A J Med Chem; 2001 Jan; 44(2):155-69. PubMed ID: 11170625 [TBL] [Abstract][Full Text] [Related]
9. HIV-1 protease flaps spontaneously close to the correct structure in simulations following manual placement of an inhibitor into the open state. Hornak V; Okur A; Rizzo RC; Simmerling C J Am Chem Soc; 2006 Mar; 128(9):2812-3. PubMed ID: 16506755 [TBL] [Abstract][Full Text] [Related]
10. Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV-1 protease inhibitors. A 3D-QSAR-CoMFA method for new antiviral drug design. Avram S; Svab I; Bologa C; Flonta ML J Cell Mol Med; 2003; 7(3):287-96. PubMed ID: 14594553 [TBL] [Abstract][Full Text] [Related]
11. Combinatorial design of nonsymmetrical cyclic urea inhibitors of aspartic protease of HIV-1. Frecer V; Burello E; Miertus S Bioorg Med Chem; 2005 Sep; 13(18):5492-501. PubMed ID: 16054372 [TBL] [Abstract][Full Text] [Related]
12. The synthesis of symmetrical and unsymmetrical P1/P1' cyclic ureas as HIV protease inhibitors. Patel M; Kaltenbach RF; Nugiel DA; McHugh RJ; Jadhav PK; Bacheler LT; Cordova BC; Klabe RM; Erickson-Viitanen S; Garber S; Reid C; Seitz SP Bioorg Med Chem Lett; 1998 May; 8(9):1077-82. PubMed ID: 9871711 [TBL] [Abstract][Full Text] [Related]
13. Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy. Lindberg J; Pyring D; Löwgren S; Rosenquist A; Zuccarello G; Kvarnström I; Zhang H; Vrang L; Classon B; Hallberg A; Samuelsson B; Unge T Eur J Biochem; 2004 Nov; 271(22):4594-602. PubMed ID: 15560801 [TBL] [Abstract][Full Text] [Related]
14. Integrating Multiple Receptor Conformation Docking and Multi Dimensional QSAR for Enhancing Accuracy of Binding Affinity Prediction. Radhika V; Jaraf HA; Kanth SS; Vijjulatha M Curr Comput Aided Drug Des; 2017; 13(2):127-142. PubMed ID: 28103770 [TBL] [Abstract][Full Text] [Related]
17. New active HIV-1 protease inhibitors derived from 3-hexanol: conformation study of the free inhibitors in crystalline state and in complex with the enzyme. Ziółkowska NE; Bujacz A; Randad RS; Erickson JW; Skálová T; Hašek J; Bujacz G Chem Biol Drug Des; 2012 May; 79(5):798-809. PubMed ID: 22296826 [TBL] [Abstract][Full Text] [Related]