207 related articles for article (PubMed ID: 23160820)
1. RBCK1, an E3 ubiquitin ligase, interacts with and ubiquinates the human pregnane X receptor.
Rana R; Coulter S; Kinyamu H; Goldstein JA
Drug Metab Dispos; 2013 Feb; 41(2):398-405. PubMed ID: 23160820
[TBL] [Abstract][Full Text] [Related]
2. Threonine-408 Regulates the Stability of Human Pregnane X Receptor through Its Phosphorylation and the CHIP/Chaperone-Autophagy Pathway.
Sugatani J; Noguchi Y; Hattori Y; Yamaguchi M; Yamazaki Y; Ikari A
Drug Metab Dispos; 2016 Jan; 44(1):137-50. PubMed ID: 26534988
[TBL] [Abstract][Full Text] [Related]
3. Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Qin M; Xin Y; Bian Y; Yang X; Xi T; Xiong J
Cells; 2022 Jan; 11(2):. PubMed ID: 35053380
[TBL] [Abstract][Full Text] [Related]
4. Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.
Ong SS; Goktug AN; Elias A; Wu J; Saunders D; Chen T
Biochem J; 2014 Apr; 459(1):193-203. PubMed ID: 24438055
[TBL] [Abstract][Full Text] [Related]
5. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
Ding X; Lichti K; Staudinger JL
Toxicol Sci; 2006 Jun; 91(2):448-55. PubMed ID: 16547076
[TBL] [Abstract][Full Text] [Related]
6. 3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
Antolino-Lobo I; Meulenbelt J; Nijmeijer SM; Maas-Bakker RF; Meijerman I; van den Berg M; van Duursen MB
Toxicol Lett; 2011 May; 203(1):82-91. PubMed ID: 21402137
[TBL] [Abstract][Full Text] [Related]
7. Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides.
Lau AJ; Yang G; Rajaraman G; Baucom CC; Chang TK
J Pharmacol Exp Ther; 2010 Dec; 335(3):771-80. PubMed ID: 20739453
[TBL] [Abstract][Full Text] [Related]
8. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
Yang J; Yan B
Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
[TBL] [Abstract][Full Text] [Related]
9. Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents.
Mani S; Huang H; Sundarababu S; Liu W; Kalpana G; Smith AB; Horwitz SB
Clin Cancer Res; 2005 Sep; 11(17):6359-69. PubMed ID: 16144941
[TBL] [Abstract][Full Text] [Related]
10. The comparative effects of diethyldithiocarbamate-copper complex with established proteasome inhibitors on expression levels of CYP1A2/3A4 and their master regulators, aryl hydrocarbon and pregnane X receptor in primary cultures of human hepatocytes.
Vrzal R; Dvorak Z
Fundam Clin Pharmacol; 2016 Dec; 30(6):585-595. PubMed ID: 27414036
[TBL] [Abstract][Full Text] [Related]
11. Broad but distinct role of pregnane x receptor on the expression of individual cytochrome p450s in human hepatocytes.
Kojima K; Nagata K; Matsubara T; Yamazoe Y
Drug Metab Pharmacokinet; 2007 Aug; 22(4):276-86. PubMed ID: 17827782
[TBL] [Abstract][Full Text] [Related]
12. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
13. Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
Sugatani J; Uchida T; Kurosawa M; Yamaguchi M; Yamazaki Y; Ikari A; Miwa M
Drug Metab Dispos; 2012 Oct; 40(10):2031-40. PubMed ID: 22829544
[TBL] [Abstract][Full Text] [Related]
14. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
[TBL] [Abstract][Full Text] [Related]
15. Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta.
Tatematsu K; Yoshimoto N; Okajima T; Tanizawa K; Kuroda S
J Biol Chem; 2008 Apr; 283(17):11575-85. PubMed ID: 18303026
[TBL] [Abstract][Full Text] [Related]
16. A concentration addition model to assess activation of the pregnane X receptor (PXR) by pesticide mixtures found in the French diet.
de Sousa G; Nawaz A; Cravedi JP; Rahmani R
Toxicol Sci; 2014 Sep; 141(1):234-43. PubMed ID: 25028461
[TBL] [Abstract][Full Text] [Related]
17. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
18. Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system.
Lemaire G; Mnif W; Pascussi JM; Pillon A; Rabenoelina F; Fenet H; Gomez E; Casellas C; Nicolas JC; Cavaillès V; Duchesne MJ; Balaguer P
Toxicol Sci; 2006 Jun; 91(2):501-9. PubMed ID: 16565514
[TBL] [Abstract][Full Text] [Related]
19. Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1.
Banerjee M; Chen T
Biochem Pharmacol; 2014 Nov; 92(2):389-402. PubMed ID: 25181459
[TBL] [Abstract][Full Text] [Related]
20. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
Li L; Stanton JD; Tolson AH; Luo Y; Wang H
Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
