These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 23164711)

  • 1. On scaffold hopping: challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans.
    Sidhu PS; Mosier PD; Zhou Q; Desai UR
    Bioorg Med Chem Lett; 2013 Jan; 23(1):355-9. PubMed ID: 23164711
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasmin regulation through allosteric, sulfated, small molecules.
    Al-Horani RA; Karuturi R; White DT; Desai UR
    Molecules; 2015 Jan; 20(1):608-24. PubMed ID: 25569517
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules.
    Nagarajan B; Sankaranarayanan NV; Patel BB; Desai UR
    PLoS One; 2017; 12(2):e0171619. PubMed ID: 28182755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8.
    Morla S; Desai UR
    Biomolecules; 2020 Aug; 10(8):. PubMed ID: 32784891
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition.
    Sidhu PS; Abdel Aziz MH; Sarkar A; Mehta AY; Zhou Q; Desai UR
    J Med Chem; 2013 Jun; 56(12):5059-70. PubMed ID: 23718540
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rational design of potent, small, synthetic allosteric inhibitors of thrombin.
    Sidhu PS; Liang A; Mehta AY; Abdel Aziz MH; Zhou Q; Desai UR
    J Med Chem; 2011 Aug; 54(15):5522-31. PubMed ID: 21714536
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of glycosaminoglycan mimetics through sulfation of polyphenols.
    Al-Horani RA; Karuturi R; Verespy S; Desai UR
    Methods Mol Biol; 2015; 1229():49-67. PubMed ID: 25325944
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors.
    Abdelfadiel EI; Gunta R; Villuri BK; Afosah DK; Sankaranarayanan NV; Desai UR
    J Med Chem; 2023 Apr; 66(7):4503-4531. PubMed ID: 37001055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin.
    Afosah DK; Verespy S; Al-Horani RA; Boothello RS; Karuturi R; Desai UR
    Bioorg Med Chem Lett; 2018 Apr; 28(6):1101-1105. PubMed ID: 29459207
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.
    Karuturi R; Al-Horani RA; Mehta SC; Gailani D; Desai UR
    J Med Chem; 2013 Mar; 56(6):2415-28. PubMed ID: 23451707
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.
    Al-Horani RA; Karuturi R; Lee M; Afosah DK; Desai UR
    PLoS One; 2016; 11(7):e0160189. PubMed ID: 27467511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Forging New Scaffolds from Old: Combining Scaffold Hopping and Hierarchical Virtual Screening for Identifying Novel Bcl-2 Inhibitors.
    Kanakaveti V; Rathinasamy S; Rayala SK; Gromiha M
    Curr Top Med Chem; 2019; 19(13):1162-1172. PubMed ID: 31210110
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.
    Verespy S; Mehta AY; Afosah D; Al-Horani RA; Desai UR
    Sci Rep; 2016 Apr; 6():24043. PubMed ID: 27053426
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The promise of sulfated synthetic small molecules as modulators of glycosaminoglycan function.
    Desai UR
    Future Med Chem; 2013 Aug; 5(12):1363-6. PubMed ID: 23919545
    [No Abstract]   [Full Text] [Related]  

  • 15. Discovery of novel sulfonated small molecules that inhibit vascular tube formation.
    Raman K; Karuturi R; Swarup VP; Desai UR; Kuberan B
    Bioorg Med Chem Lett; 2012 Jul; 22(13):4467-70. PubMed ID: 22627041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors.
    Argade MD; Mehta AY; Sarkar A; Desai UR
    J Med Chem; 2014 Apr; 57(8):3559-69. PubMed ID: 24666186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A simple, general approach of allosteric coagulation enzyme inhibition through monosulfated hydrophobic scaffolds.
    Sidhu PS; Zhou Q; Desai UR
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5716-5720. PubMed ID: 25453807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants.
    Al-Horani RA; Gailani D; Desai UR
    Thromb Res; 2015 Aug; 136(2):379-87. PubMed ID: 25935648
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel tumor necrosis factor-α (TNF-α) inhibitors from small molecule library screening for their therapeutic activity profiles against rheumatoid arthritis using target-driven approaches and binary QSAR models.
    Zaka M; Abbasi BH; Durdagi S
    J Biomol Struct Dyn; 2019 Jun; 37(9):2464-2476. PubMed ID: 30047845
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulfated, low-molecular-weight lignins are potent inhibitorsof plasmin, in addition to thrombin and factor Xa: Novel opportunity for controlling complex pathologies.
    Henry BL; Abdel Aziz M; Zhou Q; Desai UR
    Thromb Haemost; 2010 Mar; 103(3):507-15. PubMed ID: 20024500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.