BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 23169664)

  • 1. Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia.
    Whitnall M; Suryo Rahmanto Y; Huang ML; Saletta F; Lok HC; Gutiérrez L; Lázaro FJ; Fleming AJ; St Pierre TG; Mikhael MR; Ponka P; Richardson DR
    Proc Natl Acad Sci U S A; 2012 Dec; 109(50):20590-5. PubMed ID: 23169664
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation.
    Whitnall M; Suryo Rahmanto Y; Sutak R; Xu X; Becker EM; Mikhael MR; Ponka P; Richardson DR
    Proc Natl Acad Sci U S A; 2008 Jul; 105(28):9757-62. PubMed ID: 18621680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant.
    Huang ML; Becker EM; Whitnall M; Suryo Rahmanto Y; Ponka P; Richardson DR
    Proc Natl Acad Sci U S A; 2009 Sep; 106(38):16381-6. PubMed ID: 19805308
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The potential of the novel NAD
    Chiang S; Kalinowski DS; Dharmasivam M; Braidy N; Richardson DR; Huang MLH
    Pharmacol Res; 2020 May; 155():104680. PubMed ID: 32032665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Iron metabolism and mitochondrial abnormalities in Friedreich ataxia.
    Pandolfo M
    Blood Cells Mol Dis; 2002; 29(3):536-47; discussion 548-52. PubMed ID: 12547248
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A modified mouse model of Friedreich's ataxia with conditional
    Perfitt TL; Huichalaf C; Gooch R; Kuperman A; Ahn Y; Chen X; Ullas S; Hirenallur-Shanthappa D; Zhan Y; Otis D; Whiteley LO; Bulawa C; Martelli A
    Am J Physiol Heart Circ Physiol; 2024 Feb; 326(2):H357-H369. PubMed ID: 38038720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.
    Igoillo-Esteve M; Oliveira AF; Cosentino C; Fantuzzi F; Demarez C; Toivonen S; Hu A; Chintawar S; Lopes M; Pachera N; Cai Y; Abdulkarim B; Rai M; Marselli L; Marchetti P; Tariq M; Jonas JC; Boscolo M; Pandolfo M; Eizirik DL; Cnop M
    JCI Insight; 2020 Jan; 5(2):. PubMed ID: 31877117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits.
    Puccio H; Simon D; Cossée M; Criqui-Filipe P; Tiziano F; Melki J; Hindelang C; Matyas R; Rustin P; Koenig M
    Nat Genet; 2001 Feb; 27(2):181-6. PubMed ID: 11175786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.
    Martelli A; Schmucker S; Reutenauer L; Mathieu JRR; Peyssonnaux C; Karim Z; Puy H; Galy B; Hentze MW; Puccio H
    Cell Metab; 2015 Feb; 21(2):311-323. PubMed ID: 25651183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Iron metabolism in mice with partial frataxin deficiency.
    Santos MM; Miranda CJ; Levy JE; Montross LK; Cossée M; Sequeiros J; Andrews N; Koenig M; Pandolfo M
    Cerebellum; 2003; 2(2):146-53. PubMed ID: 12880182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich's ataxia.
    Weng L; Laboureur L; Wang Q; Guo L; Xu P; Gottlieb L; Lynch DR; Mesaros C; Blair IA
    Sci Rep; 2020 Sep; 10(1):15788. PubMed ID: 32978498
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia.
    Li K; Besse EK; Ha D; Kovtunovych G; Rouault TA
    Hum Mol Genet; 2008 Aug; 17(15):2265-73. PubMed ID: 18424449
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pathogenesis of cardiomyopathy in Friedreich ataxia.
    Koeppen AH; Ramirez RL; Becker AB; Bjork ST; Levi S; Santambrogio P; Parsons PJ; Kruger PC; Yang KX; Feustel PJ; Mazurkiewicz JE
    PLoS One; 2015; 10(3):e0116396. PubMed ID: 25738292
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia.
    Rötig A; de Lonlay P; Chretien D; Foury F; Koenig M; Sidi D; Munnich A; Rustin P
    Nat Genet; 1997 Oct; 17(2):215-7. PubMed ID: 9326946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of frataxin in fission yeast iron metabolism: implications for Friedreich's ataxia.
    Wang Y; Wang Y; Marcus S; Busenlehner LS
    Biochim Biophys Acta; 2014 Oct; 1840(10):3022-33. PubMed ID: 24997422
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich ataxia cellular models.
    Dong YN; McMillan E; Clark EM; Lin H; Lynch DR
    Hum Mol Genet; 2019 May; 28(10):1594-1607. PubMed ID: 30590615
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
    Becker EM; Greer JM; Ponka P; Richardson DR
    Blood; 2002 May; 99(10):3813-22. PubMed ID: 11986241
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Iron and Friedreich ataxia.
    Pandolfo M
    J Neural Transm Suppl; 2006; (70):143-6. PubMed ID: 17017521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2α phosphorylation, and the induction of downstream targets.
    Huang ML; Sivagurunathan S; Ting S; Jansson PJ; Austin CJ; Kelly M; Semsarian C; Zhang D; Richardson DR
    Am J Pathol; 2013 Sep; 183(3):745-57. PubMed ID: 23886890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia.
    Rodríguez-Pascau L; Britti E; Calap-Quintana P; Dong YN; Vergara C; Delaspre F; Medina-Carbonero M; Tamarit J; Pallardó FV; Gonzalez-Cabo P; Ros J; Lynch DR; Martinell M; Pizcueta P
    Neurobiol Dis; 2021 Jan; 148():105162. PubMed ID: 33171227
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.