BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 23171892)

  • 1. [BCL11A controls the expression of the human fetal hemoglobin].
    Labie D
    Med Sci (Paris); 2012 Nov; 28(11):923-5. PubMed ID: 23171892
    [No Abstract]   [Full Text] [Related]  

  • 2. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Developmental biology. From genetic association to genetic switch.
    Michelson AM
    Science; 2008 Dec; 322(5909):1803-4. PubMed ID: 19095932
    [No Abstract]   [Full Text] [Related]  

  • 4. Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
    Dulmovits BM; Appiah-Kubi AO; Papoin J; Hale J; He M; Al-Abed Y; Didier S; Gould M; Husain-Krautter S; Singh SA; Chan KW; Vlachos A; Allen SL; Taylor N; Marambaud P; An X; Gallagher PG; Mohandas N; Lipton JM; Liu JM; Blanc L
    Blood; 2016 Mar; 127(11):1481-92. PubMed ID: 26679864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reversing the hemoglobin switch.
    Sankaran VG; Nathan DG
    N Engl J Med; 2010 Dec; 363(23):2258-60. PubMed ID: 21121839
    [No Abstract]   [Full Text] [Related]  

  • 6. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
    Xu J; Peng C; Sankaran VG; Shao Z; Esrick EB; Chong BG; Ippolito GC; Fujiwara Y; Ebert BL; Tucker PW; Orkin SH
    Science; 2011 Nov; 334(6058):993-6. PubMed ID: 21998251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
    Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
    FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain.
    Li B; Zhu X; Hossain MA; Guy CR; Xu H; Bungert J; Pace BS
    Haematologica; 2018 Sep; 103(9):e384-e387. PubMed ID: 29622657
    [No Abstract]   [Full Text] [Related]  

  • 9. Medicine. Sickle cell disease at 100 years.
    Orkin SH; Higgs DR
    Science; 2010 Jul; 329(5989):291-2. PubMed ID: 20647458
    [No Abstract]   [Full Text] [Related]  

  • 10. KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.
    Zhou D; Liu K; Sun CW; Pawlik KM; Townes TM
    Nat Genet; 2010 Sep; 42(9):742-4. PubMed ID: 20676097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.
    Bauer DE; Orkin SH
    Curr Opin Genet Dev; 2015 Aug; 33():62-70. PubMed ID: 26375765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [BCL11A represses HbF expression and varies during ontogeny].
    Labie D
    Med Sci (Paris); 2009 May; 25(5):457-60. PubMed ID: 19480825
    [No Abstract]   [Full Text] [Related]  

  • 13. Transcriptional mechanisms underlying hemoglobin synthesis.
    Katsumura KR; DeVilbiss AW; Pope NJ; Johnson KD; Bresnick EH
    Cold Spring Harb Perspect Med; 2013 Sep; 3(9):a015412. PubMed ID: 23838521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
    Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
    Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Krüppel-Like Transcription Factor KLF1 Is Required for Optimal γ- and β-Globin Expression in Human Fetal Erythroblasts.
    Vinjamur DS; Alhashem YN; Mohamad SF; Amin P; Williams DC; Lloyd JA
    PLoS One; 2016; 11(2):e0146802. PubMed ID: 26840243
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The genetics of hemoglobin A2 regulation in sickle cell anemia.
    Griffin PJ; Sebastiani P; Edward H; Baldwin CT; Gladwin MT; Gordeuk VR; Chui DH; Steinberg MH
    Am J Hematol; 2014 Nov; 89(11):1019-23. PubMed ID: 25042611
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
    Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
    Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Post-Transcriptional Genetic Silencing of
    Esrick EB; Lehmann LE; Biffi A; Achebe M; Brendel C; Ciuculescu MF; Daley H; MacKinnon B; Morris E; Federico A; Abriss D; Boardman K; Khelladi R; Shaw K; Negre H; Negre O; Nikiforow S; Ritz J; Pai SY; London WB; Dansereau C; Heeney MM; Armant M; Manis JP; Williams DA
    N Engl J Med; 2021 Jan; 384(3):205-215. PubMed ID: 33283990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.
    Chin J; Singh M; Banzon V; Vaitkus K; Ibanez V; Kouznetsova T; Mahmud N; DeSimone J; Lavelle D
    Exp Hematol; 2009 Oct; 37(10):1131-42. PubMed ID: 19576949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of BCL11A, HBS1L-MYB, HBBP1 single nucleotide polymorphisms and the HBG2 XmnI polymorphism On Hb F levels.
    Roy P; Bhattacharya G; Mandal A; Dasgupta UB; Banerjee D; Chandra S; Das M
    Hemoglobin; 2012; 36(6):592-9. PubMed ID: 23094636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.