231 related articles for article (PubMed ID: 23173178)
1. An integrated approach to extreme thermostabilization and affinity maturation of an antibody.
McConnell AD; Spasojevich V; Macomber JL; Krapf IP; Chen A; Sheffer JC; Berkebile A; Horlick RA; Neben S; King DJ; Bowers PM
Protein Eng Des Sel; 2013 Feb; 26(2):151-64. PubMed ID: 23173178
[TBL] [Abstract][Full Text] [Related]
2. A general approach to antibody thermostabilization.
McConnell AD; Zhang X; Macomber JL; Chau B; Sheffer JC; Rahmanian S; Hare E; Spasojevic V; Horlick RA; King DJ; Bowers PM
MAbs; 2014; 6(5):1274-82. PubMed ID: 25517312
[TBL] [Abstract][Full Text] [Related]
3. Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
Finlay WJ; Cunningham O; Lambert MA; Darmanin-Sheehan A; Liu X; Fennell BJ; Mahon CM; Cummins E; Wade JM; O'Sullivan CM; Tan XY; Piche N; Pittman DD; Paulsen J; Tchistiakova L; Kodangattil S; Gill D; Hufton SE
J Mol Biol; 2009 May; 388(3):541-58. PubMed ID: 19285987
[TBL] [Abstract][Full Text] [Related]
4. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
Villani ME; Morea V; Consalvi V; Chiaraluce R; Desiderio A; Benvenuto E; Donini M
Mol Immunol; 2008 May; 45(9):2474-85. PubMed ID: 18313757
[TBL] [Abstract][Full Text] [Related]
5. Cloning and characterization of a single-chain fragment of monoclonal antibody to ACE suitable for lung endothelial targeting.
Balyasnikova IV; Berestetskaya JV; Visintine DJ; Nesterovitch AB; Adamian L; Danilov SM
Microvasc Res; 2010 Dec; 80(3):355-64. PubMed ID: 20888351
[TBL] [Abstract][Full Text] [Related]
6. Influence of canonical structure determining residues on antibody affinity and stability.
Clark LA; Demarest SJ; Eldredge J; Jarpe MB; Li Y; Simon K; van Vlijmen HW
J Struct Biol; 2014 Feb; 185(2):223-7. PubMed ID: 23994046
[TBL] [Abstract][Full Text] [Related]
7. Engineering antibodies for stability and efficient folding.
Honegger A
Handb Exp Pharmacol; 2008; (181):47-68. PubMed ID: 18071941
[TBL] [Abstract][Full Text] [Related]
8. Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.
Tiller KE; Li L; Kumar S; Julian MC; Garde S; Tessier PM
J Biol Chem; 2017 Oct; 292(40):16638-16652. PubMed ID: 28778924
[TBL] [Abstract][Full Text] [Related]
9. Development of an affinity-matured humanized anti-epidermal growth factor receptor antibody for cancer immunotherapy.
Nakanishi T; Maru T; Tahara K; Sanada H; Umetsu M; Asano R; Kumagai I
Protein Eng Des Sel; 2013 Feb; 26(2):113-22. PubMed ID: 23118340
[TBL] [Abstract][Full Text] [Related]
10. The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin.
Giles I; Lambrianides N; Latchman D; Chen P; Chukwuocha R; Isenberg D; Rahman A
Arthritis Res Ther; 2005; 7(1):R47-56. PubMed ID: 15642142
[TBL] [Abstract][Full Text] [Related]
11. Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis.
Choi BD; Gedeon PC; Kuan CT; Sanchez-Perez L; Archer GE; Bigner DD; Sampson JH
J Immunol Methods; 2013 Sep; 395(1-2):14-20. PubMed ID: 23806556
[TBL] [Abstract][Full Text] [Related]
12. T cell receptor engineering.
Stone JD; Chervin AS; Aggen DH; Kranz DM
Methods Enzymol; 2012; 503():189-222. PubMed ID: 22230570
[TBL] [Abstract][Full Text] [Related]
13. A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
Tu C; Terraube V; Tam AS; Stochaj W; Fennell BJ; Lin L; Stahl M; LaVallie ER; Somers W; Finlay WJ; Mosyak L; Bard J; Cunningham O
J Biol Chem; 2016 Jan; 291(3):1267-76. PubMed ID: 26515064
[TBL] [Abstract][Full Text] [Related]
14. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
Wu H; Nie Y; Huse WD; Watkins JD
J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035
[TBL] [Abstract][Full Text] [Related]
15. Enhanced antibody affinity to Japanese encephalitis virus E protein by phage display.
Hong WW; Yen YH; Wu SC
Biochem Biophys Res Commun; 2007 Apr; 356(1):124-8. PubMed ID: 17350601
[TBL] [Abstract][Full Text] [Related]
16. A study of the structural correlates of affinity maturation: antibody affinity as a function of chemical interactions, structural plasticity and stability.
David MP; Asprer JJ; Ibana JS; Concepcion GP; Padlan EA
Mol Immunol; 2007 Feb; 44(6):1342-51. PubMed ID: 16854467
[TBL] [Abstract][Full Text] [Related]
17. Secretion from bacterial versus mammalian cells yields a recombinant scFv with variable folding properties.
Vendel MC; Favis M; Snyder WB; Huang F; Capili AD; Dong J; Glaser SM; Miller BR; Demarest SJ
Arch Biochem Biophys; 2012 Oct; 526(2):188-93. PubMed ID: 22230329
[TBL] [Abstract][Full Text] [Related]
18. Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.
van den Beucken T; van Neer N; Sablon E; Desmet J; Celis L; Hoogenboom HR; Hufton SE
J Mol Biol; 2001 Jul; 310(3):591-601. PubMed ID: 11439026
[TBL] [Abstract][Full Text] [Related]
19. A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold.
Desiderio A; Franconi R; Lopez M; Villani ME; Viti F; Chiaraluce R; Consalvi V; Neri D; Benvenuto E
J Mol Biol; 2001 Jul; 310(3):603-15. PubMed ID: 11439027
[TBL] [Abstract][Full Text] [Related]
20. Construction and molecular characterization of mouse single-chain variable fragment antibodies against Burkholderia mallei and Burkholderia pseudomallei.
Kim HS; Tsai S; Zou N; Lo SC; Wear DJ; Izadjoo MJ
J Immunol Methods; 2011 Feb; 365(1-2):101-9. PubMed ID: 21172353
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]