BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

600 related articles for article (PubMed ID: 23177916)

  • 1. Bridging the gap: bitopic ligands of G-protein-coupled receptors.
    Lane JR; Sexton PM; Christopoulos A
    Trends Pharmacol Sci; 2013 Jan; 34(1):59-66. PubMed ID: 23177916
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs.
    Valant C; Sexton PM; Christopoulos A
    Mol Interv; 2009 Jun; 9(3):125-35. PubMed ID: 19592673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors.
    Valant C; Robert Lane J; Sexton PM; Christopoulos A
    Annu Rev Pharmacol Toxicol; 2012; 52():153-78. PubMed ID: 21910627
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry.
    Fronik P; Gaiser BI; Sejer Pedersen D
    J Med Chem; 2017 May; 60(10):4126-4134. PubMed ID: 28140580
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors.
    Mohr K; Schmitz J; Schrage R; Tränkle C; Holzgrabe U
    Angew Chem Int Ed Engl; 2013 Jan; 52(2):508-16. PubMed ID: 23225228
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Advances in G protein-coupled receptor allostery: from function to structure.
    Christopoulos A
    Mol Pharmacol; 2014 Nov; 86(5):463-78. PubMed ID: 25061106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.
    Keov P; Sexton PM; Christopoulos A
    Neuropharmacology; 2011 Jan; 60(1):24-35. PubMed ID: 20637785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent Advances in the Drug Discovery and Development of Dualsteric/ Bitopic Activators of G Protein-Coupled Receptors.
    Reinecke BA; Wang H; Zhang Y
    Curr Top Med Chem; 2019; 19(26):2378-2392. PubMed ID: 31833462
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT; Watson J; Bertekap R; Alt A
    Biochem Pharmacol; 2011 Mar; 81(6):691-702. PubMed ID: 21184747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors.
    Feng Z; Hu G; Ma S; Xie XQ
    AAPS J; 2015 Sep; 17(5):1080-95. PubMed ID: 25940084
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric ligands for G protein-coupled receptors: a novel strategy with attractive therapeutic opportunities.
    De Amici M; Dallanoce C; Holzgrabe U; Tränkle C; Mohr K
    Med Res Rev; 2010 May; 30(3):463-549. PubMed ID: 19557759
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Emerging opportunities for allosteric modulation of G-protein coupled receptors.
    Wang CI; Lewis RJ
    Biochem Pharmacol; 2013 Jan; 85(2):153-62. PubMed ID: 22975406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. When simple agonism is not enough: emerging modalities of GPCR ligands.
    Smith NJ; Bennett KA; Milligan G
    Mol Cell Endocrinol; 2011 Jan; 331(2):241-7. PubMed ID: 20654693
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.
    Müller CE; Schiedel AC; Baqi Y
    Pharmacol Ther; 2012 Sep; 135(3):292-315. PubMed ID: 22728155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric modulation of G-protein coupled receptors.
    Jensen AA; Spalding TA
    Eur J Pharm Sci; 2004 Mar; 21(4):407-20. PubMed ID: 14998571
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity.
    Antony J; Kellershohn K; Mohr-Andrä M; Kebig A; Prilla S; Muth M; Heller E; Disingrini T; Dallanoce C; Bertoni S; Schrobang J; Tränkle C; Kostenis E; Christopoulos A; Höltje HD; Barocelli E; De Amici M; Holzgrabe U; Mohr K
    FASEB J; 2009 Feb; 23(2):442-50. PubMed ID: 18842964
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives.
    Urwyler S
    Pharmacol Rev; 2011 Mar; 63(1):59-126. PubMed ID: 21228259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. G-protein-coupled receptor allosterism: the promise and the problem(s).
    Christopoulos A; May LT; Avlani VA; Sexton PM
    Biochem Soc Trans; 2004 Nov; 32(Pt 5):873-7. PubMed ID: 15494038
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identifying novel modulators of G protein-coupled receptors via interaction at allosteric sites.
    Presland J
    Curr Opin Drug Discov Devel; 2005 Sep; 8(5):567-76. PubMed ID: 16159018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. How Ligands Illuminate GPCR Molecular Pharmacology.
    Wacker D; Stevens RC; Roth BL
    Cell; 2017 Jul; 170(3):414-427. PubMed ID: 28753422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.