BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 23178376)

  • 1. Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.
    Volanakis EJ; Boothby MR; Sherr CJ
    Exp Hematol; 2013 Apr; 41(4):377-86. PubMed ID: 23178376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia.
    Volanakis EJ; Williams RT; Sherr CJ
    Blood; 2009 Nov; 114(20):4451-9. PubMed ID: 19759355
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
    Treanor LM; Volanakis EJ; Zhou S; Lu T; Sherr CJ; Sorrentino BP
    Blood; 2011 May; 117(20):5453-62. PubMed ID: 21427293
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
    Medyouf H; Gao X; Armstrong F; Gusscott S; Liu Q; Gedman AL; Matherly LH; Schultz KR; Pflumio F; You MJ; Weng AP
    Blood; 2010 Feb; 115(6):1175-84. PubMed ID: 20008304
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice.
    Shank-Calvo JA; Draheim K; Bhasin M; Kelliher MA
    Oncogene; 2006 May; 25(21):3023-31. PubMed ID: 16407836
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.
    Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F
    Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.
    Randle DH; Zindy F; Sherr CJ; Roussel MF
    Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9654-9. PubMed ID: 11481442
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of function tp53 mutations do not accelerate the onset of myc-induced T-cell acute lymphoblastic leukaemia in the zebrafish.
    Gutierrez A; Feng H; Stevenson K; Neuberg DS; Calzada O; Zhou Y; Langenau DM; Look AT
    Br J Haematol; 2014 Jul; 166(1):84-90. PubMed ID: 24690081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High-risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells.
    Young FM; Campbell A; Emo KL; Jansson J; Wang PY; Jordan CT; Mullen CA
    Biol Blood Marrow Transplant; 2008 Jun; 14(6):622-30. PubMed ID: 18489987
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
    Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P
    Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines.
    Park YB; Park MJ; Kimura K; Shimizu K; Lee SH; Yokota J
    Cancer Genet Cytogenet; 2002 Mar; 133(2):105-11. PubMed ID: 11943335
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.
    Fasseu M; Aplan PD; Chopin M; Boissel N; Bories JC; Soulier J; von Boehmer H; Sigaux F; Regnault A
    Blood; 2007 Oct; 110(7):2610-9. PubMed ID: 17507663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Consistent inactivation of p19(Arf) but not p15(Ink4b) in murine myeloid cells transformed in vivo by deregulated c-Myc.
    Haviernik P; Schmidt M; Hu X; Wolff L
    Oncogene; 2003 Mar; 22(11):1600-10. PubMed ID: 12642863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.
    Kong G; Du J; Liu Y; Meline B; Chang YI; Ranheim EA; Wang J; Zhang J
    J Biol Chem; 2013 Jun; 288(25):18219-27. PubMed ID: 23673656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
    Uhrbom L; Dai C; Celestino JC; Rosenblum MK; Fuller GN; Holland EC
    Cancer Res; 2002 Oct; 62(19):5551-8. PubMed ID: 12359767
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia.
    Genescà E; Lazarenkov A; Morgades M; Berbis G; Ruíz-Xivillé N; Gómez-Marzo P; Ribera J; Juncà J; González-Pérez A; Mercadal S; Guardia R; Artola MT; Moreno MJ; Martínez-López J; Zamora L; Barba P; Gil C; Tormo M; Cladera A; Novo A; Pratcorona M; Nomdedeu J; González-Campos J; Almeida M; Cervera J; Montesinos P; Batlle M; Vives S; Esteve J; Feliu E; Solé F; Orfao A; Ribera JM
    J Hematol Oncol; 2018 Jul; 11(1):96. PubMed ID: 30041662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf.
    Signer RA; Montecino-Rodriguez E; Witte ON; Dorshkind K
    Genes Dev; 2008 Nov; 22(22):3115-20. PubMed ID: 19056891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developmental strategies for evasion of Arf tumor suppression.
    Volanakis EJ; Sherr CJ
    Cell Cycle; 2010 Jan; 9(1):14-5. PubMed ID: 20009580
    [No Abstract]   [Full Text] [Related]  

  • 19. Genetic Alterations in the INK4a/ARF Locus: Effects on Melanoma Development and Progression.
    Ming Z; Lim SY; Rizos H
    Biomolecules; 2020 Oct; 10(10):. PubMed ID: 33076392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p16(Ink4a) interferes with Abelson virus transformation by enhancing apoptosis.
    Sachs Z; Sharpless NE; DePinho RA; Rosenberg N
    J Virol; 2004 Apr; 78(7):3304-11. PubMed ID: 15016851
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.