195 related articles for article (PubMed ID: 23180142)
1. Mitochondrial accumulation of a lipophilic cation conjugated to an ionisable group depends on membrane potential, pH gradient and pK(a): implications for the design of mitochondrial probes and therapies.
Finichiu PG; James AM; Larsen L; Smith RA; Murphy MP
J Bioenerg Biomembr; 2013 Feb; 45(1-2):165-73. PubMed ID: 23180142
[TBL] [Abstract][Full Text] [Related]
2. Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: implications for mitochondria-specific therapies and probes.
Porteous CM; Logan A; Evans C; Ledgerwood EC; Menon DK; Aigbirhio F; Smith RA; Murphy MP
Biochim Biophys Acta; 2010 Sep; 1800(9):1009-17. PubMed ID: 20621583
[TBL] [Abstract][Full Text] [Related]
3. Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker.
Prag HA; Kula-Alwar D; Pala L; Caldwell ST; Beach TE; James AM; Saeb-Parsy K; Krieg T; Hartley RC; Murphy MP
Mol Pharm; 2020 Sep; 17(9):3526-3540. PubMed ID: 32692564
[TBL] [Abstract][Full Text] [Related]
4. Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers.
Ross MF; Filipovska A; Smith RA; Gait MJ; Murphy MP
Biochem J; 2004 Nov; 383(Pt. 3):457-68. PubMed ID: 15270716
[TBL] [Abstract][Full Text] [Related]
5. Conjugation of Triphenylphosphonium Cation to Hydrophobic Moieties to Prepare Mitochondria-Targeting Nanocarriers.
Guzman-Villanueva D; Mendiola MR; Nguyen HX; Yambao F; Yu N; Weissig V
Methods Mol Biol; 2019; 2000():183-189. PubMed ID: 31148015
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.
Filipovska A; Kelso GF; Brown SE; Beer SM; Smith RA; Murphy MP
J Biol Chem; 2005 Jun; 280(25):24113-26. PubMed ID: 15831495
[TBL] [Abstract][Full Text] [Related]
7. Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells.
Ross MF; Prime TA; Abakumova I; James AM; Porteous CM; Smith RA; Murphy MP
Biochem J; 2008 May; 411(3):633-45. PubMed ID: 18294140
[TBL] [Abstract][Full Text] [Related]
8. Mitochondrial Membrane Potential (ΔΨ) Fluctuations Associated with the Metabolic States of Mitochondria.
Teodoro JS; Palmeira CM; Rolo AP
Methods Mol Biol; 2018; 1782():109-119. PubMed ID: 29850996
[TBL] [Abstract][Full Text] [Related]
9. Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore.
Blaikie FH; Brown SE; Samuelsson LM; Brand MD; Smith RA; Murphy MP
Biosci Rep; 2006 Jun; 26(3):231-43. PubMed ID: 16850251
[TBL] [Abstract][Full Text] [Related]
10. Differential effects of metabolic inhibitors on cellular and mitochondrial uptake of organic cations in rat liver.
Steen H; Maring JG; Meijer DK
Biochem Pharmacol; 1993 Feb; 45(4):809-18. PubMed ID: 8452555
[TBL] [Abstract][Full Text] [Related]
11. A mitochondria-targeted derivative of ascorbate: MitoC.
Finichiu PG; Larsen DS; Evans C; Larsen L; Bright TP; Robb EL; Trnka J; Prime TA; James AM; Smith RA; Murphy MP
Free Radic Biol Med; 2015 Dec; 89():668-78. PubMed ID: 26453920
[TBL] [Abstract][Full Text] [Related]
12. Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation.
Pala L; Senn HM; Caldwell ST; Prime TA; Warrington S; Bright TP; Prag HA; Wilson C; Murphy MP; Hartley RC
Front Chem; 2020; 8():783. PubMed ID: 33033715
[TBL] [Abstract][Full Text] [Related]
13. The Evaluation of Mitochondrial Membrane Potential Using Fluorescent Dyes or a Membrane-Permeable Cation (TPP
Teodoro JS; Machado IF; Castela AC; Rolo AP; Palmeira CM
Methods Mol Biol; 2020; 2184():197-213. PubMed ID: 32808227
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial membrane potential (ΔΨ) fluctuations associated with the metabolic states of mitochondria.
Palmeira CM; Rolo AP
Methods Mol Biol; 2012; 810():89-101. PubMed ID: 22057562
[TBL] [Abstract][Full Text] [Related]
15. Lipophilic triphenylphosphonium cations inhibit mitochondrial electron transport chain and induce mitochondrial proton leak.
Trnka J; Elkalaf M; Anděl M
PLoS One; 2015; 10(4):e0121837. PubMed ID: 25927600
[TBL] [Abstract][Full Text] [Related]
16. Measurement of plasma membrane potential in isolated rat hepatocytes using the lipophilic cation, tetraphenylphosphonium: correction of probe intracellular binding and mitochondrial accumulation.
Saito S; Murakami Y; Miyauchi S; Kamo N
Biochim Biophys Acta; 1992 Nov; 1111(2):221-30. PubMed ID: 1329961
[TBL] [Abstract][Full Text] [Related]
17. Delivery of bioactive molecules to mitochondria in vivo.
Smith RA; Porteous CM; Gane AM; Murphy MP
Proc Natl Acad Sci U S A; 2003 Apr; 100(9):5407-12. PubMed ID: 12697897
[TBL] [Abstract][Full Text] [Related]
18. Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria-Targeted Triphenylphosphonium Constructs.
Uno S; Harkiss AH; Chowdhury R; Caldwell ST; Prime TA; James AM; Gallagher B; Prudent J; Hartley RC; Murphy MP
Chembiochem; 2023 Jun; 24(11):e202200774. PubMed ID: 36917207
[TBL] [Abstract][Full Text] [Related]
19. Penetrating cations enhance uncoupling activity of anionic protonophores in mitochondria.
Antonenko YN; Khailova LS; Knorre DA; Markova OV; Rokitskaya TI; Ilyasova TM; Severina II; Kotova EA; Karavaeva YE; Prikhodko AS; Severin FF; Skulachev VP
PLoS One; 2013; 8(4):e61902. PubMed ID: 23626747
[TBL] [Abstract][Full Text] [Related]
20. Semitelechelic HPMA copolymers functionalized with triphenylphosphonium as drug carriers for membrane transduction and mitochondrial localization.
Callahan J; Kopecek J
Biomacromolecules; 2006 Aug; 7(8):2347-56. PubMed ID: 16903681
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]