BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

808 related articles for article (PubMed ID: 23183047)

  • 1. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
    Finlay DK; Rosenzweig E; Sinclair LV; Feijoo-Carnero C; Hukelmann JL; Rolf J; Panteleyev AA; Okkenhaug K; Cantrell DA
    J Exp Med; 2012 Dec; 209(13):2441-53. PubMed ID: 23183047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB.
    Finlay DK
    Biochem Soc Trans; 2013 Apr; 41(2):681-6. PubMed ID: 23514176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
    Kim JS; Sklarz T; Banks LB; Gohil M; Waickman AT; Skuli N; Krock BL; Luo CT; Hu W; Pollizzi KN; Li MO; Rathmell JC; Birnbaum MJ; Powell JD; Jordan MS; Koretzky GA
    Nat Immunol; 2013 Jun; 14(6):611-8. PubMed ID: 23644504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.
    Rao RR; Li Q; Gubbels Bupp MR; Shrikant PA
    Immunity; 2012 Mar; 36(3):374-87. PubMed ID: 22425248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
    D'Souza AD; Parish IA; McKay SE; Kaech SM; Shadel GS
    Am J Pathol; 2011 Jun; 178(6):2740-51. PubMed ID: 21641396
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation.
    Zhu Y; Pereira RO; O'Neill BT; Riehle C; Ilkun O; Wende AR; Rawlings TA; Zhang YC; Zhang Q; Klip A; Shiojima I; Walsh K; Abel ED
    Mol Endocrinol; 2013 Jan; 27(1):172-84. PubMed ID: 23204326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
    Pollizzi KN; Patel CH; Sun IH; Oh MH; Waickman AT; Wen J; Delgoffe GM; Powell JD
    J Clin Invest; 2015 May; 125(5):2090-108. PubMed ID: 25893604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism.
    Wan X; Liu Y; Zhao Y; Sun X; Fan D; Guo L
    PLoS One; 2017; 12(9):e0184213. PubMed ID: 28886081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.
    Shrestha S; Yang K; Wei J; Karmaus PW; Neale G; Chi H
    Proc Natl Acad Sci U S A; 2014 Oct; 111(41):14858-63. PubMed ID: 25271321
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.
    Macintyre AN; Finlay D; Preston G; Sinclair LV; Waugh CM; Tamas P; Feijoo C; Okkenhaug K; Cantrell DA
    Immunity; 2011 Feb; 34(2):224-36. PubMed ID: 21295499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Natural killer group 2D and CD28 receptors differentially activate mammalian/mechanistic target of rapamycin to alter murine effector CD8+ T-cell differentiation.
    McQueen B; Trace K; Whitman E; Bedsworth T; Barber A
    Immunology; 2016 Mar; 147(3):305-20. PubMed ID: 26661515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T; Cui L; Wang H; Wang H; Han N
    J Transl Med; 2018 Jun; 16(1):164. PubMed ID: 29898734
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PDGF receptor-β uses Akt/mTORC1 signaling node to promote high glucose-induced renal proximal tubular cell collagen I (α2) expression.
    Das F; Ghosh-Choudhury N; Venkatesan B; Kasinath BS; Ghosh Choudhury G
    Am J Physiol Renal Physiol; 2017 Aug; 313(2):F291-F307. PubMed ID: 28424212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Foxp3 and Toll-like receptor signaling balance T
    Gerriets VA; Kishton RJ; Johnson MO; Cohen S; Siska PJ; Nichols AG; Warmoes MO; de Cubas AA; MacIver NJ; Locasale JW; Turka LA; Wells AD; Rathmell JC
    Nat Immunol; 2016 Dec; 17(12):1459-1466. PubMed ID: 27695003
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.
    Pollizzi KN; Sun IH; Patel CH; Lo YC; Oh MH; Waickman AT; Tam AJ; Blosser RL; Wen J; Delgoffe GM; Powell JD
    Nat Immunol; 2016 Jun; 17(6):704-11. PubMed ID: 27064374
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
    Miyazaki M; Miyazaki K; Chen S; Chandra V; Wagatsuma K; Agata Y; Rodewald HR; Saito R; Chang AN; Varki N; Kawamoto H; Murre C
    Genes Dev; 2015 Feb; 29(4):409-25. PubMed ID: 25691468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima.
    Dekanty A; Lavista-Llanos S; Irisarri M; Oldham S; Wappner P
    J Cell Sci; 2005 Dec; 118(Pt 23):5431-41. PubMed ID: 16278294
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S; Zou Z; Nie P; Wen R; Xiao Y; Tang J
    PLoS One; 2015; 10(7):e0132880. PubMed ID: 26176608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
    Toschi A; Lee E; Gadir N; Ohh M; Foster DA
    J Biol Chem; 2008 Dec; 283(50):34495-9. PubMed ID: 18945681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances.
    Chen X; Zhu Y; Wang Z; Zhu H; Pan Q; Su S; Dong Y; Li L; Zhang H; Wu L; Lou X; Liu S
    J Proteomics; 2016 Mar; 136():13-24. PubMed ID: 26844761
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.