251 related articles for article (PubMed ID: 23184952)
1. Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor.
Dennis MD; Kimball SR; Jefferson LS
J Biol Chem; 2013 Jan; 288(1):10-9. PubMed ID: 23184952
[TBL] [Abstract][Full Text] [Related]
2. Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis.
Dennis MD; Jefferson LS; Kimball SR
J Biol Chem; 2012 Dec; 287(51):42890-9. PubMed ID: 23105104
[TBL] [Abstract][Full Text] [Related]
3. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
4. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
Zhang L; Kimball SR; Jefferson LS; Shenberger JS
Free Radic Biol Med; 2009 Jun; 46(11):1500-9. PubMed ID: 19281842
[TBL] [Abstract][Full Text] [Related]
5. Nutrient-induced stimulation of protein synthesis in mouse skeletal muscle is limited by the mTORC1 repressor REDD1.
Gordon BS; Williamson DL; Lang CH; Jefferson LS; Kimball SR
J Nutr; 2015 Apr; 145(4):708-13. PubMed ID: 25716553
[TBL] [Abstract][Full Text] [Related]
6. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
[TBL] [Abstract][Full Text] [Related]
7. Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis.
Coffman K; Yang B; Lu J; Tetlow AL; Pelliccio E; Lu S; Guo DC; Tang C; Dong MQ; Tamanoi F
J Biol Chem; 2014 Feb; 289(8):4723-34. PubMed ID: 24403073
[TBL] [Abstract][Full Text] [Related]
8. Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: effect of obesity vs. REDD1 deficiency.
Williamson DL; Li Z; Tuder RM; Feinstein E; Kimball SR; Dungan CM
J Appl Physiol (1985); 2014 Aug; 117(3):246-56. PubMed ID: 24876363
[TBL] [Abstract][Full Text] [Related]
9. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
Lekmine F; Uddin S; Sassano A; Parmar S; Brachmann SM; Majchrzak B; Sonenberg N; Hay N; Fish EN; Platanias LC
J Biol Chem; 2003 Jul; 278(30):27772-80. PubMed ID: 12759354
[TBL] [Abstract][Full Text] [Related]
10. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
Schalm SS; Fingar DC; Sabatini DM; Blenis J
Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
[TBL] [Abstract][Full Text] [Related]
11. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
[TBL] [Abstract][Full Text] [Related]
12. The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif.
Nojima H; Tokunaga C; Eguchi S; Oshiro N; Hidayat S; Yoshino K; Hara K; Tanaka N; Avruch J; Yonezawa K
J Biol Chem; 2003 May; 278(18):15461-4. PubMed ID: 12604610
[TBL] [Abstract][Full Text] [Related]
13. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L; Harris TE; Roth RA; Lawrence JC
J Biol Chem; 2007 Jul; 282(27):20036-44. PubMed ID: 17510057
[TBL] [Abstract][Full Text] [Related]
14. mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.
Dodd KM; Yang J; Shen MH; Sampson JR; Tee AR
Oncogene; 2015 Apr; 34(17):2239-50. PubMed ID: 24931163
[TBL] [Abstract][Full Text] [Related]
15. The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
Böhm R; Imseng S; Jakob RP; Hall MN; Maier T; Hiller S
Mol Cell; 2021 Jun; 81(11):2403-2416.e5. PubMed ID: 33852892
[TBL] [Abstract][Full Text] [Related]
16. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
[TBL] [Abstract][Full Text] [Related]
17. Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition.
Dunlop EA; Dodd KM; Seymour LA; Tee AR
Cell Signal; 2009 Jul; 21(7):1073-84. PubMed ID: 19272448
[TBL] [Abstract][Full Text] [Related]
18. Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1.
Beugnet A; Wang X; Proud CG
J Biol Chem; 2003 Oct; 278(42):40717-22. PubMed ID: 12912989
[TBL] [Abstract][Full Text] [Related]
19. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet.
Kimball SR; Ravi S; Gordon BS; Dennis MD; Jefferson LS
J Nutr; 2015 Nov; 145(11):2496-502. PubMed ID: 26400964
[TBL] [Abstract][Full Text] [Related]
20. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Dowling RJ; Topisirovic I; Alain T; Bidinosti M; Fonseca BD; Petroulakis E; Wang X; Larsson O; Selvaraj A; Liu Y; Kozma SC; Thomas G; Sonenberg N
Science; 2010 May; 328(5982):1172-6. PubMed ID: 20508131
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]