BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 23185365)

  • 1. The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination.
    Wei J; Yuan Y; Jin C; Chen H; Leng L; He F; Wang J
    PLoS One; 2012; 7(11):e49567. PubMed ID: 23185365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
    Zhang J; Lei Z; Huang Z; Zhang X; Zhou Y; Luo Z; Zeng W; Su J; Peng C; Chen X
    Oncotarget; 2016 Nov; 7(48):79557-79571. PubMed ID: 27791197
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
    Wang W; Huang X; Xin HB; Fu M; Xue A; Wu ZH
    J Biol Chem; 2015 May; 290(21):13372-85. PubMed ID: 25861989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.
    Lamothe B; Besse A; Campos AD; Webster WK; Wu H; Darnay BG
    J Biol Chem; 2007 Feb; 282(6):4102-12. PubMed ID: 17135271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6.
    Min Y; Wi SM; Kang JA; Yang T; Park CS; Park SG; Chung S; Shim JH; Chun E; Lee KY
    Cell Death Dis; 2016 Jul; 7(7):e2313. PubMed ID: 27468689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PP4R1 subunit of protein phosphatase PP4 targets TRAF2 and TRAF6 to mediate inhibition of NF-κB activation.
    Hadweh P; Habelhah H; Kieff E; Mosialos G; Hatzivassiliou E
    Cell Signal; 2014 Dec; 26(12):2730-7. PubMed ID: 25134449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational analysis of TRAF6 reveals a conserved functional role of the RING dimerization interface and a potentially necessary but insufficient role of RING-dependent TRAF6 polyubiquitination towards NF-κB activation.
    Megas C; Hatzivassiliou EG; Yin Q; Marinopoulou E; Hadweh P; Vignali DA; Mosialos G
    Cell Signal; 2011 May; 23(5):772-7. PubMed ID: 21185369
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling.
    Ohtake F; Saeki Y; Ishido S; Kanno J; Tanaka K
    Mol Cell; 2016 Oct; 64(2):251-266. PubMed ID: 27746020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Porcine Reproductive and Respiratory Syndrome Virus Antagonizes JAK/STAT3 Signaling via nsp5, Which Induces STAT3 Degradation.
    Yang L; Wang R; Ma Z; Xiao Y; Nan Y; Wang Y; Lin S; Zhang YJ
    J Virol; 2017 Feb; 91(3):. PubMed ID: 27881658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Mediates Ubiquitination-Dependent STAT3 Activation upon Salmonella enterica Serovar Typhimurium Infection.
    Ruan HH; Zhang Z; Wang SY; Nickels LM; Tian L; Qiao JJ; Zhu J
    Infect Immun; 2017 Aug; 85(8):. PubMed ID: 28507064
    [No Abstract]   [Full Text] [Related]  

  • 11. Loganin alleviates LPS-activated intestinal epithelial inflammation by regulating TLR4/NF-κB and JAK/STAT3 signaling pathways.
    Wang JW; Pan YB; Cao YQ; Wang C; Jiang WD; Zhai WF; Lu JG
    Kaohsiung J Med Sci; 2020 Apr; 36(4):257-264. PubMed ID: 31859422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitin-specific peptidase USP22 negatively regulates the STAT signaling pathway by deubiquitinating SIRT1.
    Ao N; Liu Y; Feng H; Bian X; Li Z; Gu B; Zhao X; Liu Y
    Cell Physiol Biochem; 2014; 33(6):1863-75. PubMed ID: 24969755
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.
    Moon G; Kim J; Min Y; Wi SM; Shim JH; Chun E; Lee KY
    Cell Signal; 2015 Dec; 27(12):2524-33. PubMed ID: 26432169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction.
    Gargan S; Ahmed S; Mahony R; Bannan C; Napoletano S; O'Farrelly C; Borrow P; Bergin C; Stevenson NJ
    EBioMedicine; 2018 Apr; 30():203-216. PubMed ID: 29580840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination.
    Chen H; Wu Y; Zhang Y; Jin L; Luo L; Xue B; Lu C; Zhang X; Yin Z
    FEBS Lett; 2006 May; 580(13):3145-52. PubMed ID: 16697380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.
    Zhang H; Hu H; Greeley N; Jin J; Matthews AJ; Ohashi E; Caetano MS; Li HS; Wu X; Mandal PK; McMurray JS; Moghaddam SJ; Sun SC; Watowich SS
    Nat Commun; 2014 Dec; 5():5798. PubMed ID: 25503582
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration.
    Xiao N; Li H; Luo J; Wang R; Chen H; Chen J; Wang P
    Biochem J; 2012 Feb; 441(3):979-86. PubMed ID: 22029577
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation.
    Min Y; Kim MJ; Lee S; Chun E; Lee KY
    Autophagy; 2018; 14(8):1347-1358. PubMed ID: 29929436
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chordate PIAS proteins act as conserved repressors of the TRAF6 self-polyubiquitination.
    Fu X; Wang R; Li M; Yan X; Huang H; Li J; Chen S; Yue Z; Chen S; Li Y; Dong M; Xu A; Huang S
    Dev Comp Immunol; 2020 Mar; 104():103554. PubMed ID: 31758961
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.
    Park ES; Choi S; Shin B; Yu J; Yu J; Hwang JM; Yun H; Chung YH; Choi JS; Choi Y; Rho J
    J Biol Chem; 2015 Apr; 290(15):9660-73. PubMed ID: 25716317
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.